The burden of disease due to COVID-19 in Sweden 2020–2021: A disability-adjusted life years (DALYs) study

por Shedrawy, Jad, Ernst, Patricia, Lönnroth, Knut, Nyberg, Fredrik
Publicado 2023

Developmentally-induced Mll1 loss reveals defects in postnatal haematopoiesis

por Gan, Tao, Jude, Craig D., Zaffuto, Kristin, Ernst, Patricia
Publicado 2010

Does lineage plasticity enable escape from CAR-T cell therapy? Lessons from MLL-r leukemia

por Liao, Wenjuan, Kohler, M. Eric, Fry, Terry, Ernst, Patricia
Publicado 2021

Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets

por Lin, Wenchu, Francis, Joshua M., Li, Hong, Gao, Xiaoping, Pedamallu, Chandra Sekhar, Ernst, Patricia, Meyerson, Matthew
Publicado 2016

The Histone Methyltransferase Activity of MLL1 Is Dispensable for Hematopoiesis and Leukemogenesis

por Mishra, Bibhu P., Zaffuto, Kristin M., Artinger, Erika L., Org, Tonis, Mikkola, Hanna K.A., Cheng, Chao, Djabali, Malek, Ernst, Patricia
Publicado 2014

Runx1 Loss Minimally Impacts Long-Term Hematopoietic Stem Cells

por Cai, Xiongwei, Gaudet, Justin J., Mangan, James K., Chen, Michael J., De Obaldia, Maria Elena, Oo, Zaw, Ernst, Patricia, Speck, Nancy A.
Publicado 2011

MLL1 is required for PAX7 expression and satellite cell self-renewal in mice

por Addicks, Gregory C., Brun, Caroline E., Sincennes, Marie-Claude, Saber, John, Porter, Christopher J., Francis Stewart, A., Ernst, Patricia, Rudnicki, Michael A.
Publicado 2019

Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis

por Yang, Weiwei, Trahan, G. Devon, Howell, Elizabeth D., Speck, Nancy A., Jones, Kenneth L., Gillen, Austin E., Riemondy, Kent, Hesselberth, Jay, Bryder, David, Ernst, Patricia
Publicado 2020

Menin is necessary for long term maintenance of meningioma-1 driven leukemia

por Libbrecht, Clara, Xie, Hongbo M., Kingsley, Molly C., Haladyna, Jessica N., Riedel, Simone S., Alikarami, Fatemeh, Lenard, Alexandra, McGeehan, Gerard M., Ernst, Patricia, Bernt, Kathrin M.
Publicado 2021

Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation

por Nguyen, Nhu, Gudmundsson, Kristbjorn O., Soltis, Anthony R., Oakley, Kevin, Roy, Kartik R., Han, Yufen, Gurnari, Carmelo, Maciejewski, Jaroslaw P., Crouch, Gary, Ernst, Patricia, Dalgard, Clifton L., Du, Yang
Publicado 2021

Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia

por Hurtz, Christian, Chan, Lai N., Geng, Huimin, Ballabio, Erica, Xiao, Gang, Deb, Gauri, Khoury, Haytham, Chen, Chun-Wei, Armstrong, Scott A., Chen, Jianjun, Ernst, Patricia, Melnick, Ari, Milne, Thomas, Müschen, Markus
Publicado 2019

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

por Sparbier, Christina E., Gillespie, Andrea, Gomez, Juliana, Kumari, Nishi, Motazedian, Ali, Chan, Kah Lok, Bell, Charles C., Gilan, Omer, Chan, Yih-Chih, Popp, Sarah, Gough, Daniel J., Eckersley-Maslin, Melanie A., Dawson, Sarah-Jane, Lehner, Paul J., Sutherland, Kate D., Ernst, Patricia, McGeehan, Gerard M., Lam, Enid Y. N., Burr, Marian L., Dawson, Mark A.
Publicado 2023

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

por Rogawski, David S., Deng, Jing, Li, Hao, Miao, Hongzhi, Borkin, Dmitry, Purohit, Trupta, Song, Jiho, Chase, Jennifer, Li, Shuangjiang, Ndoj, Juliano, Klossowski, Szymon, Kim, EunGi, Mao, Fengbiao, Zhou, Bo, Ropa, James, Krotoska, Marta Z., Jin, Zhuang, Ernst, Patricia, Feng, Xiaomin, Huang, Gang, Nishioka, Kenichi, Kelly, Samantha, He, Miao, Wen, Bo, Sun, Duxin, Muntean, Andrew, Dou, Yali, Maillard, Ivan, Cierpicki, Tomasz, Grembecka, Jolanta
Publicado 2021