KnowLife: a versatile approach for constructing a large knowledge graph for biomedical sciences

por Ernst, Patrick, Siu, Amy, Weikum, Gerhard
Publicado 2015

Structural analysis of biological targets by host:guest crystal lattice engineering

por Ernst, Patrick, Plückthun, Andreas, Mittl, Peer R. E.
Publicado 2019

Legislation against girl circumcision: a cultural psychological understanding of prohibition

por Graamans, Ernst Patrick, Smet, Eefje, ten Have, Steven
Publicado 2019

454 A Human 3D Model of Duchenne Muscular Dystrophy Cardiomyopathy to Investigate Calcium Regulation and Mitochondrial Dysfunction

por Ernst, Patrick, Dora, Michaela, Zhou, Lufang, Ogle, Brenda, Kamdar, Forum
Publicado 2023

Characterization of the far-red fluorescent probe MitoView 633 for dynamic mitochondrial membrane potential measurement

por Ernst, Patrick, Kim, Seulhee, Yang, Zengqiao, Liu, Xiaoguang Margaret, Zhou, Lufang
Publicado 2023

Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation

por Ernst, Patrick, Bidwell, Philip A., Dora, Michaela, Thomas, David D., Kamdar, Forum
Publicado 2023

Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity

por Hansen, Simon, Stüber, Jakob C., Ernst, Patrick, Koch, Alexander, Bojar, Daniel, Batyuk, Alexander, Plückthun, Andreas
Publicado 2017

Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts

por Ernst, Patrick, Honegger, Annemarie, van der Valk, Floor, Ewald, Christina, Mittl, Peer R. E., Plückthun, Andreas
Publicado 2019

Lessons learned from implementing alternative rites in the fight against female genital mutilation/cutting

por Graamans, Ernst Patrick, Zolnikov, Tara Rava, Smet, Eefje, Nguura, Peter Ngatia, Leshore, Lepantas Charles, Have, Steven ten
Publicado 2019

Mitochondrial‐Mediated Oxidative Ca(2+)/Calmodulin‐Dependent Kinase II Activation Induces Early Afterdepolarizations in Guinea Pig Cardiomyocytes: An In Silico Study

por Yang, Ruilin, Ernst, Patrick, Song, Jiajia, Liu, Xiaoguang M., Huke, Sabine, Wang, Shuxin, Zhang, Jianyi Jay, Zhou, Lufang
Publicado 2018

Unexpected dynamics in femtomolar complexes of binding proteins with peptides

por Cucuzza, Stefano, Sitnik, Malgorzata, Jurt, Simon, Michel, Erich, Dai, Wenzhao, Müntener, Thomas, Ernst, Patrick, Häussinger, Daniel, Plückthun, Andreas, Zerbe, Oliver
Publicado 2023

Antibody–Drug Conjugate to Treat Meningiomas

por Chen, Kai, Si, Yingnan, Ou, Jianfa, Guan, Jia-Shiung, Kim, Seulhee, Ernst, Patrick, Zhang, Ya, Zhou, Lufang, Han, Xiaosi, Liu, Xiaoguang (Margaret)
Publicado 2021

Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation

por Afroz, Tariq, Hock, Eva-Maria, Ernst, Patrick, Foglieni, Chiara, Jambeau, Melanie, Gilhespy, Larissa A. B., Laferriere, Florent, Maniecka, Zuzanna, Plückthun, Andreas, Mittl, Peer, Paganetti, Paolo, Allain, Frédéric H. T., Polymenidou, Magdalini
Publicado 2017

Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control

por Schmid, Markus, Ernst, Patrick, Honegger, Annemarie, Suomalainen, Maarit, Zimmermann, Martina, Braun, Lukas, Stauffer, Sarah, Thom, Cristian, Dreier, Birgit, Eibauer, Matthias, Kipar, Anja, Vogel, Viola, Greber, Urs F., Medalia, Ohad, Plückthun, Andreas
Publicado 2018

Anti-SSTR2 Antibody-drug Conjugate for Neuroendocrine Tumor Therapy

por Si, Yingnan, Kim, Seulhee, Ou, Jianfa, Lu, Yun, Ernst, Patrick, Chen, Kai, Whitt, Jason, Carter, Angela M., Markert, James M., Bibb, James A., Chen, Herbert, Zhou, Lufang, Jaskula-Sztul, Renata, Liu, Xiaoguang “Margaret”
Publicado 2020

Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism

por Deluigi, Mattia, Klipp, Alexander, Klenk, Christoph, Merklinger, Lisa, Eberle, Stefanie A., Morstein, Lena, Heine, Philipp, Mittl, Peer R. E., Ernst, Patrick, Kamenecka, Theodore M., He, Yuanjun, Vacca, Santiago, Egloff, Pascal, Honegger, Annemarie, Plückthun, Andreas
Publicado 2021

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action

por Kast, Florian, Schwill, Martin, Stüber, Jakob C., Pfundstein, Svende, Nagy-Davidescu, Gabriela, Rodríguez, Josep M. Monné, Seehusen, Frauke, Richter, Christian P., Honegger, Annemarie, Hartmann, Karen Patricia, Weber, Thomas G., Kroener, Felix, Ernst, Patrick, Piehler, Jacob, Plückthun, Andreas
Publicado 2021

Ablation of lncRNA Miat attenuates pathological hypertrophy and heart failure

por Yang, Liu, Deng, Jianxin, Ma, Wenxia, Qiao, Aijun, Xu, Shiyue, Yu, Yang, Boriboun, Chan, Kang, Xiang, Han, Dunzheng, Ernst, Patrick, Zhou, Lufang, Shi, Jiawei, Zhang, Eric, Li, Tao-Sheng, Qiu, Hongyu, Nakagawa, Shinichi, Blackshaw, Seth, Zhang, Jianyi, Qin, Gangjian
Publicado 2021

Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization

por Friedrich, Nikolas, Stiegeler, Emanuel, Glögl, Matthias, Lemmin, Thomas, Hansen, Simon, Kadelka, Claus, Wu, Yufan, Ernst, Patrick, Maliqi, Liridona, Foulkes, Caio, Morin, Mylène, Eroglu, Mustafa, Liechti, Thomas, Ivan, Branislav, Reinberg, Thomas, Schaefer, Jonas V., Karakus, Umut, Ursprung, Stephan, Mann, Axel, Rusert, Peter, Kouyos, Roger D., Robinson, John A., Günthard, Huldrych F., Plückthun, Andreas, Trkola, Alexandra
Publicado 2021