Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine

por Errico, Silvia, Ramshini, Hassan, Capitini, Claudia, Canale, Claudio, Spaziano, Martina, Barbut, Denise, Calamai, Martino, Zasloff, Michael, Oropesa-Nuñez, Reinier, Vendruscolo, Michele, Chiti, Fabrizio
Publicado 2021

Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes

por Errico, Silvia, Lucchesi, Giacomo, Odino, Davide, Osman, Enass Youssef, Cascella, Roberta, Neri, Lorenzo, Capitini, Claudia, Calamai, Martino, Bemporad, Francesco, Cecchi, Cristina, Kinney, William A., Barbut, Denise, Relini, Annalisa, Canale, Claudio, Caminati, Gabriella, Limbocker, Ryan, Vendruscolo, Michele, Zasloff, Michael, Chiti, Fabrizio
Publicado 2023

A Brain-Permeable Aminosterol Regulates Cell Membranes to Mitigate the Toxicity of Diverse Pore-Forming Agents

por Kreiser, Ryan P., Wright, Aidan K., Sasser, Liam R., Rinauro, Dillon J., Gabriel, Justus M., Hsu, Claire M., Hurtado, Jorge A., McKenzie, Tristan L., Errico, Silvia, Albright, J. Alex, Richardson, Lance, Jaffett, Victor A., Riegner, Dawn E., Nguyen, Lam T., LeForte, Kathleen, Zasloff, Michael, Hollows, Jared E., Chiti, Fabrizio, Vendruscolo, Michele, Limbocker, Ryan
Publicado 2022

Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers

por Limbocker, Ryan, Staats, Roxine, Chia, Sean, Ruggeri, Francesco S., Mannini, Benedetta, Xu, Catherine K., Perni, Michele, Cascella, Roberta, Bigi, Alessandra, Sasser, Liam R., Block, Natalie R., Wright, Aidan K., Kreiser, Ryan P., Custy, Edward T., Meisl, Georg, Errico, Silvia, Habchi, Johnny, Flagmeier, Patrick, Kartanas, Tadas, Hollows, Jared E., Nguyen, Lam T., LeForte, Kathleen, Barbut, Denise, Kumita, Janet R., Cecchi, Cristina, Zasloff, Michael, Knowles, Tuomas P. J., Dobson, Christopher M., Chiti, Fabrizio, Vendruscolo, Michele
Publicado 2021