Advancements in the Development of HIF-1α-Activated Protein Switches for Use in Enzyme Prodrug Therapy

por Wright, R. Clay, Khakhar, Arjun, Eshleman, James R., Ostermeier, Marc
Publicado 2014

Nanopore sequencing detects structural variants in cancer

por Norris, Alexis L., Workman, Rachael E., Fan, Yunfan, Eshleman, James R., Timp, Winston
Publicado 2016

Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective

por Chen, Guoli, Yang, Zhaohai, Eshleman, James R., Netto, George J., Lin, Ming-Tseh
Publicado 2016

Analytical Validation of SOD2 Genotyping

por Debeljak, Marija, Riel, Stacy, Lin, Ming-Tseh, Eshleman, James R., Paller, Channing J.
Publicado 2022

Mutational profiling of colorectal cancers with microsatellite instability

por Lin, Elaine I., Tseng, Li-Hui, Gocke, Christopher D., Reil, Stacy, Le, Dung T., Azad, Nilofer S., Eshleman, James R.
Publicado 2015

Val16A SOD2 Polymorphism Promotes Epithelial–Mesenchymal Transition Antagonized by Muscadine Grape Skin Extract in Prostate Cancer Cells

por Sweeney, Janae D., Debeljak, Marija, Riel, Stacy, Millena, Ana Cecilia, Eshleman, James R., Paller, Channing J., Odero-Marah, Valerie
Publicado 2021

Clinical detection and categorization of uncommon and concomitant mutations involving BRAF

por Zheng, Gang, Tseng, Li-Hui, Chen, Guoli, Haley, Lisa, Illei, Peter, Gocke, Christopher D., Eshleman, James R., Lin, Ming-Tseh
Publicado 2015

Clinical mutational profiling and categorization of BRAF mutations in melanomas using next generation sequencing

por Lokhandwala, Parvez M., Tseng, Li-Hui, Rodriguez, Erika, Zheng, Gang, Pallavajjalla, Aparna, Gocke, Christopher D., Eshleman, James R., Lin, Ming-Tseh
Publicado 2019

Analysis of Polymorphisms and Haplotype Structure of the Human Thymidylate Synthase Genetic Region: A Tool for Pharmacogenetic Studies

por Ghosh, Soma, Hossain, M. Zulfiquer, Borges, Michael, Goggins, Michael G., Ingersoll, Roxann G., Eshleman, James R., Klein, Alison P., Kern, Scott E.
Publicado 2012

Colorectal cancer in patients of advanced age is associated with increased incidence of BRAF p.V600E mutation and mismatch repair deficiency

por Christenson, Eric S., Tsai, Hua-Ling, Le, Dung T., Jaffee, Elizabeth M., Dudley, Jonathan, Xian, Rena R., Gocke, Christopher D., Eshleman, James R., Lin, Ming-Tseh
Publicado 2023

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer

por Sui, Guoping, Zhou, Shaoyu, Wang, Jean, Canto, Marcia, Lee, Edward E, Eshleman, James R, Montgomery, Elizabeth A, Sidransky, David, Califano, Joseph A, Maitra, Anirban
Publicado 2006

IDH1 and IDH2 mutations in lung adenocarcinomas: Evidences of subclonal evolution

por Rodriguez, Erika F., De Marchi, Federico, Lokhandwala, Parvez M., Belchis, Deborah, Xian, Rena, Gocke, Christopher D., Eshleman, James R., Illei, Peter, Li, Ming‐Tseh
Publicado 2020

Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias

por Hong, Seung-Mo, Heaphy, Christopher M., Shi, Chanjuan, Eo, Soo-Heang, Cho, HyungJun, Meeker, Alan K., Eshleman, James R., Hruban, Ralph H., Goggins, Michael
Publicado 2010

Functional CDKN2A assay identifies frequent deleterious alleles misclassified as variants of uncertain significance

por Kimura, Hirokazu, Paranal, Raymond M, Nanda, Neha, Wood, Laura D, Eshleman, James R, Hruban, Ralph H, Goggins, Michael G, Klein, Alison P, Roberts, Nicholas J
Publicado 2022

Pancreatic cancer pathology viewed in the light of evolution

por Noë, Michaël, Hong, Seung-Mo, Wood, Laura D., Thompson, Elizabeth D., Roberts, Nicholas J., Goggins, Michael G., Klein, Alison P., Eshleman, James R., Kern, Scott E., Hruban, Ralph H.
Publicado 2021

Heterogeneity of resistance mutations detectable by next-generation sequencing in TKI-treated lung adenocarcinoma

por Belchis, Deborah A., Tseng, Li-Hui, Gniadek, Thomas, Haley, Lisa, Lokhandwala, Parvez, Illei, Peter, Gocke, Christopher D., Forde, Patrick, Brahmer, Julie, Askin, Frederic B., Eshleman, James R., Lin, Ming-Tseh
Publicado 2016

Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation

por Gondek, Lukasz P., Zheng, Gang, Ghiaur, Gabriel, DeZern, Amy E., Matsui, William, Yegnasubramanian, Srinivasan, Lin, Ming-Tseh, Levis, Mark, Eshleman, James R., Varadhan, Ravi, Tucker, Noah, Jones, Richard, Gocke, Christopher D.
Publicado 2016

Mechanism of delayed cell death following simultaneous CRISPR-Cas9 targeting in pancreatic cancers

por Teh, Selina Shiqing K., Halper-Stromberg, Eitan, Morsberger, Laura, Bennett, Alexis, Bowland, Kirsten, Skaist, Alyza, Cai, Fidel, Liang, Hong, Hruban, Ralph H., Roberts, Nicholas J., Scharpf, Robert B., Zou, Ying S., Eshleman, James R.
Publicado 2023

Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer

por Yachida, Shinichi, Jones, Siân, Bozic, Ivana, Antal, Tibor, Leary, Rebecca, Fu, Baojin, Kamiyama, Mihoko, Hruban, Ralph H., Eshleman, James R., Nowak, Martin A., Velculescu, Victor E., Kinzler, Kenneth W., Vogelstein, Bert, Iacobuzio-Donahue, Christine A.
Publicado 2010

Clinical mutational profiling of 1006 lung cancers by next generation sequencing

por Illei, Peter B., Belchis, Deborah, Tseng, Li-Hui, Nguyen, Doreen, De Marchi, Federico, Haley, Lisa, Riel, Stacy, Beierl, Katie, Zheng, Gang, Brahmer, Julie R., Askin, Frederic B., Gocke, Christopher D., Eshleman, James R., Forde, Patrick M., Lin, Ming-Tseh
Publicado 2017