Altered Gene Expression Associated with microRNA Binding Site Polymorphisms

por Võsa, Urmo, Esko, Tõnu, Kasela, Silva, Annilo, Tarmo
Publicado 2015

RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations

por Haller, Toomas, Kals, Mart, Esko, Tõnu, Mägi, Reedik, Fischer, Krista
Publicado 2015

Within-Trait Heterogeneity in Age Group Differences in Personality Domains and Facets: Implications for the Development and Coherence of Personality Traits

por Mõttus, René, Realo, Anu, Allik, Jüri, Esko, Tõnu, Metspalu, Andres, Johnson, Wendy
Publicado 2015

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

por Joshi, Peter K., Fischer, Krista, Schraut, Katharina E., Campbell, Harry, Esko, Tõnu, Wilson, James F.
Publicado 2016

MADloy: robust detection of mosaic loss of chromosome Y from genotype-array-intensity data

por González, Juan R., López-Sánchez, Marcos, Cáceres, Alejandro, Puig, Pere, Esko, Tonu, Pérez-Jurado, Luis A.
Publicado 2020

Mendelian Randomization Identifies the Potential Causal Impact of Dietary Patterns on Circulating Blood Metabolites

por Taba, Nele, Valge, Hanna-Kristel, Metspalu, Andres, Esko, Tõnu, Wilson, James F., Fischer, Krista, Pirastu, Nicola
Publicado 2021

Predicting COVID-19 Transmission to Inform the Management of Mass Events: Model-Based Approach

por Donnat, Claire, Bunbury, Freddy, Kreindler, Jack, Liu, David, Filippidis, Filippos T, Esko, Tonu, El-Osta, Austen, Harris, Matthew
Publicado 2021

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification

por Läll, Kristi, Lepamets, Maarja, Palover, Marili, Esko, Tõnu, Metspalu, Andres, Tõnisson, Neeme, Padrik, Peeter, Mägi, Reedik, Fischer, Krista
Publicado 2019

Haplotype Phasing and Inheritance of Copy Number Variants in Nuclear Families

por Palta, Priit, Kaplinski, Lauris, Nagirnaja, Liina, Veidenberg, Andres, Möls, Märt, Nelis, Mari, Esko, Tõnu, Metspalu, Andres, Laan, Maris, Remm, Maido
Publicado 2015

Circulating glucuronic acid predicts healthspan and longevity in humans and mice

por Ho, Andrew, Sinick, Jonah, Esko, Tõnu, Fischer, Krista, Menni, Cristina, Zierer, Jonas, Matey-Hernandez, Maria, Fortney, Kristen, Morgen, Eric K.
Publicado 2019

Structural Genomic Variation as Risk Factor for Idiopathic Recurrent Miscarriage

por Nagirnaja, Liina, Palta, Priit, Kasak, Laura, Rull, Kristiina, Christiansen, Ole B, Nielsen, Henriette S, Steffensen, Rudi, Esko, Tõnu, Remm, Maido, Laan, Maris
Publicado 2014

Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms

por Mathieu, Samuel, Briend, Mewen, Abner, Erik, Couture, Christian, Li, Zhonglin, Bossé, Yohan, Thériault, Sébastien, Esko, Tõnu, Arsenault, Benoit J., Mathieu, Patrick
Publicado 2022

Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study

por Gagnon, Eloi, Mitchell, Patricia L., Manikpurage, Hasanga D., Abner, Erik, Taba, Nele, Esko, Tõnu, Ghodsian, Nooshin, Thériault, Sébastien, Mathieu, Patrick, Arsenault, Benoit J.
Publicado 2023

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

por Haller, Toomas, Leitsalu, Liis, Fischer, Krista, Nuotio, Marja-Liisa, Esko, Tõnu, Boomsma, Dorothea Irene, Kyvik, Kirsten Ohm, Spector, Tim D., Perola, Markus, Metspalu, Andres
Publicado 2017

Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records

por Tasa, Tõnis, Krebs, Kristi, Kals, Mart, Mägi, Reedik, Lauschke, Volker M., Haller, Toomas, Puurand, Tarmo, Remm, Maido, Esko, Tõnu, Metspalu, Andres, Vilo, Jaak, Milani, Lili
Publicado 2018

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank

por James, Glen, Reisberg, Sulev, Lepik, Kaido, Galwey, Nicholas, Avillach, Paul, Kolberg, Liis, Mägi, Reedik, Esko, Tõnu, Alexander, Myriam, Waterworth, Dawn, Loomis, A. Katrina, Vilo, Jaak
Publicado 2019

A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

por Macdonald-Dunlop, Erin, Taba, Nele, Klarić, Lucija, Frkatović, Azra, Walker, Rosie, Hayward, Caroline, Esko, Tõnu, Haley, Chris, Fischer, Krista, Wilson, James F., Joshi, Peter K.
Publicado 2022

OTTERS: a powerful TWAS framework leveraging summary-level reference data

por Dai, Qile, Zhou, Geyu, Zhao, Hongyu, Võsa, Urmo, Franke, Lude, Battle, Alexis, Teumer, Alexander, Lehtimäki, Terho, Raitakari, Olli T., Esko, Tõnu, Epstein, Michael P., Yang, Jingjing
Publicado 2023

Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript

por Puig, Marta, Castellano, David, Pantano, Lorena, Giner-Delgado, Carla, Izquierdo, David, Gayà-Vidal, Magdalena, Lucas-Lledó, José Ignacio, Esko, Tõnu, Terao, Chikashi, Matsuda, Fumihiko, Cáceres, Mario
Publicado 2015

Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

por Mitt, Mario, Kals, Mart, Pärn, Kalle, Gabriel, Stacey B, Lander, Eric S, Palotie, Aarno, Ripatti, Samuli, Morris, Andrew P, Metspalu, Andres, Esko, Tõnu, Mägi, Reedik, Palta, Priit
Publicado 2017