New Mechanisms for Vascular Control of Inflammation Mediated by Natural Anticoagulant Proteins

por Esmon, Charles T.
Publicado 2002

Protein C anticoagulant system—anti-inflammatory effects

por Esmon, Charles T.
Publicado 2011

The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness

por Esmon, Charles T
Publicado 2001

Interactions between the innate immune and blood coagulation systems

por Esmon, Charles T.
Publicado 2004

Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis

por Opal, Steven M, Esmon, Charles T
Publicado 2003

A critical role of endothelial cell protein C receptor in the intestinal homeostasis in experimental colitis

por Kondreddy, Vijay, Keshava, Shiva, Esmon, Charles T., Pendurthi, Usha R., Rao, L. Vijaya Mohan
Publicado 2020

Rab GTPases Regulate Endothelial Cell Protein C Receptor-Mediated Endocytosis and Trafficking of Factor VIIa

por Nayak, Ramesh C., Keshava, Shiva, Esmon, Charles T., Pendurthi, Usha R., Rao, L. Vijaya Mohan
Publicado 2013

Evidence for the important role of inflammation in xenotransplantation

por Li, Juan, Hara, Hidetaka, Wang, Yi, Esmon, Charles, Cooper, David K. C., Iwase, Hayato
Publicado 2019

An engineered activated factor V for the prevention and treatment of acute traumatic coagulopathy and bleeding in mice

por Joseph, Bilgimol Chumappumkal, Miyazawa, Byron Y., Esmon, Charles T., Cohen, Mitchell J., von Drygalski, Annette, Mosnier, Laurent O.
Publicado 2022

Extracellular histones are major mediators of death in sepsis

por Xu, Jun, Zhang, Xiaomei, Pelayo, Rosana, Monestier, Marc, Ammollo, Concetta T., Semeraro, Fabrizio, Taylor, Fletcher B., Esmon, Naomi, Lupu, Florea, Esmon, Charles T.
Publicado 2009

Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development

por Schaffner, Florence, Yokota, Naho, Carneiro-Lobo, Tatiana, Kitano, Maki, Schaffer, Michael, Anderson, G. Mark, Mueller, Barbara M., Esmon, Charles T., Ruf, Wolfram
Publicado 2013

Endogenous Histones Function as Alarmins in Sterile Inflammatory Liver Injury Through Toll-like Receptor 9 in Mice

por Huang, Hai, Evankovich, John, Yan, Wei, Nace, Gary, Zhang, Lemeng, Ross, Mark, Liao, Xinghua, Billiar, Timothy, Xu, Jun, Esmon, Charles T, Tsung, Allan
Publicado 2011

Treatment with Activated Protein C (aPC) Is Protective during the Development of Myocardial Fibrosis: An Angiotensin II Infusion Model in Mice

por Sopel, Mryanda J., Rosin, Nicole L., Falkenham, Alec G., Bezuhly, Michael, Esmon, Charles T., Lee, Timothy D. G., Liwski, Robert S., Légaré, Jean-Francois
Publicado 2012

Vascular Immunotargeting to Endothelial Determinant ICAM-1 Enables Optimal Partnering of Recombinant scFv-Thrombomodulin Fusion with Endogenous Cofactor

por Greineder, Colin F., Chacko, Ann-Marie, Zaytsev, Sergei, Zern, Blaine J., Carnemolla, Ronald, Hood, Elizabeth D., Han, Jingyan, Ding, Bi-Sen, Esmon, Charles T., Muzykantov, Vladimir R.
Publicado 2013

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions

por Ogbechi, Joy, Ruf, Marie-Thérèse, Hall, Belinda S., Bodman-Smith, Katherine, Vogel, Moritz, Wu, Hua-Lin, Stainer, Alexander, Esmon, Charles T., Ahnström, Josefin, Pluschke, Gerd, Simmonds, Rachel E.
Publicado 2015

Overexpression of the Endothelial Protein C Receptor Is Detrimental during Pneumonia-Derived Gram-negative Sepsis (Melioidosis)

por Kager, Liesbeth M., Schouten, Marcel, Wiersinga, W. Joost, de Boer, J. Daan, Lattenist, Lionel C. W., Roelofs, Joris J. T. H., Meijers, Joost C. M., Levi, Marcel, Dondorp, Arjen M., Esmon, Charles T., van 't Veer, Cornelis, van der Poll, Tom
Publicado 2013

Activated protein C reverses epigenetically sustained p66(Shc) expression in plaque-associated macrophages in diabetes

por Shahzad, Khurrum, Gadi, Ihsan, Nazir, Sumra, Al-Dabet, Moh’d Mohanad, Kohli, Shrey, Bock, Fabian, Breitenstein, Lukas, Ranjan, Satish, Fuchs, Tina, Halloul, Zuhir, Nawroth, Peter. P., Pelicci, Pier Giuseppe, Braun-Dullaeus, Ruediger C., Camerer, Eric, Esmon, Charles T., Isermann, Berend
Publicado 2018

Blocking human protein C anticoagulant activity improves clotting defects of hemophilia mice expressing human protein C

por Jiang, Miao, Yang, Fei, Jiang, Yizhi, Cheng, Lu, Han, Jingjing, Yi, Jiawei, Zhang, Guige, Ma, Zhenni, Cao, Lijuan, Zuo, Bin, Zhou, Lixia, Huang, Lulu, Niu, Siying, Xia, Zhisong, Zhou, Xuefeng, Bai, Xia, Esmon, Naomi L., Ruan, Changgeng, Xia, Lijun, Han, Yue, Esmon, Charles T., Wu, Depei, Xu, Jun
Publicado 2022

Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dep...

por Borissoff, Julian I., Otten, Jeroen J. T., Heeneman, Sylvia, Leenders, Peter, van Oerle, René, Soehnlein, Oliver, Loubele, Sarah T. B. G., Hamulyák, Karly, Hackeng, Tilman M., Daemen, Mat J. A. P., Degen, Jay L., Weiler, Hartmut, Esmon, Charles T., van Ryn, Joanne, Biessen, Erik A. L., Spronk, Henri M. H., ten Cate, Hugo
Publicado 2013