Substituted Purines as High-Affinity Histamine H(3) Receptor Ligands

por Espinosa-Bustos, Christian, Leitzbach, Luisa, Añazco, Tito, Silva, María J., del Campo, Andrea, Castro-Alvarez, Alejandro, Stark, Holger, Salas, Cristian O.
Publicado 2022

Synthesis and Pharmacophore Modelling of 2,6,9-Trisubstituted Purine Derivatives and Their Potential Role as Apoptosis-Inducing Agents in Cancer Cell Lines

por Calderón-Arancibia, Jeannette, Espinosa-Bustos, Christian, Cañete-Molina, Álvaro, Tapia, Ricardo A., Faúndez, Mario, Torres, Maria Jose, Aguirre, Adam, Paulino, Margot, Salas, Cristian O.
Publicado 2015

Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment...

por Bertrand, Jeanluc, Dostálová, Hana, Kryštof, Vladimír, Jorda, Radek, Delgado, Thalía, Castro-Alvarez, Alejandro, Mella, Jaime, Cabezas, David, Faúndez, Mario, Espinosa-Bustos, Christian, Salas, Cristian O.
Publicado 2022

Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands

por Mella-Raipán, Jaime A., Lagos, Carlos F., Recabarren-Gajardo, Gonzalo, Espinosa-Bustos, Christian, Romero-Parra, Javier, Pessoa-Mahana, Hernán, Iturriaga-Vásquez, Patricio, Pessoa-Mahana, Carlos David
Publicado 2013

New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase

por Espinosa-Bustos, Christian, Ortiz Pérez, Mariana, Gonzalez-Gonzalez, Alonzo, Zarate, Ana María, Rivera, Gildardo, Belmont-Díaz, Javier A., Saavedra, Emma, Cuellar, Mauricio A., Vázquez, Karina, Salas, Cristian O.
Publicado 2022

Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays

por O. Salas, Cristian, Zarate, Ana Maria, Kryštof, Vladimir, Mella, Jaime, Faundez, Mario, Brea, Jose, Loza, María Isabel, Brito, Ivan, Hendrychová, Denisa, Jorda, Radek, Cabrera, Alan R., Tapia, Ricardo A., Espinosa-Bustos, Christian
Publicado 2019

A New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo

por Zárate, Ana María, Espinosa-Bustos, Christian, Guerrero, Simón, Fierro, Angélica, Oyarzún-Ampuero, Felipe, Quest, Andrew F. G., Di Marcotullio, Lucia, Loricchio, Elena, Caimano, Miriam, Calcaterra, Andrea, González-Quiroz, Matías, Aguirre, Adam, Meléndez, Jaime, Salas, Cristian O.
Publicado 2021