Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer

por Espinoza-Fonseca, L Michel
Publicado 2005

Probing the effects of nonannular lipid binding on the stability of the calcium pump SERCA

por Espinoza-Fonseca, L. Michel
Publicado 2019

Structural Basis for the Function of the C-Terminal Proton Release Pathway in the Calcium Pump

por Espinoza-Fonseca, L. Michel
Publicado 2021

Atomic-Level Characterization of the Activation Mechanism of SERCA by Calcium

por Espinoza-Fonseca, L. Michel, Thomas, David D.
Publicado 2011

Linking Biochemical and Structural States of SERCA: Achievements, Challenges, and New Opportunities

por Aguayo-Ortiz, Rodrigo, Espinoza-Fonseca, L. Michel
Publicado 2020

Atomistic Structure and Dynamics of the Ca(2+)-ATPase Bound to Phosphorylated Phospholamban

por Aguayo-Ortiz, Rodrigo, Espinoza-Fonseca, L. Michel
Publicado 2020

Microsecond Molecular Dynamics Simulations of Mg(2+)- and K(+)- Bound E1 Intermediate States of the Calcium Pump

por Espinoza-Fonseca, L. Michel, Autry, Joseph M., Thomas, David D.
Publicado 2014

A novel machine learning-based screening identifies statins as inhibitors of the calcium pump SERCA

por Cruz-Cortés, Carlos, Velasco-Saavedra, M. Andrés, Fernández-de Gortari, Eli, Guerrero-Serna, Guadalupe, Aguayo-Ortiz, Rodrigo, Espinoza-Fonseca, L. Michel
Publicado 2023

A multiscale approach for bridging the gap between potency, efficacy, and safety of small molecules directed at membrane proteins

por Aguayo-Ortiz, Rodrigo, Creech, Jeffery, Jiménez-Vázquez, Eric N., Guerrero-Serna, Guadalupe, Wang, Nulang, da Rocha, Andre Monteiro, Herron, Todd J., Espinoza-Fonseca, L. Michel
Publicado 2021

Fluorescence lifetime imaging microscopy reveals sodium pump dimers in live cells

por Seflova, Jaroslava, Habibi, Nima R., Yap, John Q., Cleary, Sean R., Fang, Xuan, Kekenes-Huskey, Peter M., Espinoza-Fonseca, L. Michel, Bossuyt, Julie B., Robia, Seth L.
Publicado 2022

Dwarf open reading frame (DWORF) is a direct activator of the sarcoplasmic reticulum calcium pump SERCA

por Fisher, M'Lynn E, Bovo, Elisa, Aguayo-Ortiz, Rodrigo, Cho, Ellen E, Pribadi, Marsha P, Dalton, Michael P, Rathod, Nishadh, Lemieux, M Joanne, Espinoza-Fonseca, L Michel, Robia, Seth L, Zima, Aleksey V, Young, Howard S
Publicado 2021

Structural Basis for the Limited Response to Oxidative and Thiol-Conjugating Agents by Triosephosphate Isomerase From the Photosynthetic Bacteria Synechocystis

por Castro-Torres, Eduardo, Jimenez-Sandoval, Pedro, Fernández-de Gortari, Eli, López-Castillo, Margarita, Baruch-Torres, Noe, López-Hidalgo, Marisol, Peralta-Castro, Antolín, Díaz-Quezada, Corina, Sotelo-Mundo, Rogerio R., Benitez-Cardoza, Claudia G., Espinoza-Fonseca, L. Michel, Ochoa-Leyva, Adrian, Brieba, Luis G.
Publicado 2018