Targeting JAK/STAT Signaling Antagonizes Resistance to Oncolytic Reovirus Therapy Driven by Prior Infection with HTLV-1 in Models of T-Cell Lymphoma

por Islam, Shariful, Espitia, Claudia M., Persky, Daniel O., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2021

Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas

por Carew, Jennifer S., Espitia, Claudia M., Zhao, Weiguo, Mita, Monica M., Mita, Alain C., Nawrocki, Steffan T.
Publicado 2017

Targeted CUL4A inhibition synergizes with cisplatin to yield long-term survival in models of head and neck squamous cell carcinoma through a DDB2-mediated mechanism

por Jones, Trace M., Espitia, Claudia M., Ooi, Aikseng, Bauman, Julie E., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2022

Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus

por Kelly, Kevin R., Espitia, Claudia M., Zhao, Weiguo, Wendlandt, Erik, Tricot, Guido, Zhan, Fenghuang, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2015

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models

por Mahalingam, Devalingam, Carew, Jennifer S., Espitia, Claudia M., Cool, Robbert H., Giles, Francis J., de Jong, Steven, Nawrocki, Steffan T.
Publicado 2019

Targeting NEDDylation is a Novel Strategy to Attenuate Cisplatin-induced Nephrotoxicity

por Jones, Trace M., Espitia, Claudia M., Chipollini, Juan, Lee, Benjamin R., Wertheim, Jason A., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2023

Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis

por Espitia, Claudia M, Zhao, Weiguo, Saldarriaga, Omar, Osorio, Yaneth, Harrison, Lisa M, Cappello, Michael, Travi, Bruno L, Melby, Peter C
Publicado 2010

Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy

por Kelly, Kevin R., Espitia, Claudia M., Zhao, Weiguo, Wu, Kaijin, Visconte, Valeria, Anwer, Faiz, Calton, Christine M., Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2017

ELR510444 Inhibits Tumor Growth and Angiogenesis by Abrogating HIF Activity and Disrupting Microtubules in Renal Cell Carcinoma

por Carew, Jennifer S., Esquivel, Juan A., Espitia, Claudia M., Schultes, Christoph M., Mülbaier, Marcel, Lewis, Joe D., Janssen, Bernd, Giles, Francis J., Nawrocki, Steffan T.
Publicado 2012

ABCG2 Overexpression Contributes to Pevonedistat Resistance

por Kathawala, Rishil J., Espitia, Claudia M., Jones, Trace M., Islam, Shariful, Gupta, Pranav, Zhang, Yun-Kai, Chen, Zhe-Sheng, Carew, Jennifer S., Nawrocki, Steffan T.
Publicado 2020

Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes

por Espitia, Claudia M, Saldarriaga, Omar A, Travi, Bruno L, Osorio, E Yaneth, Hernandez, Alvaro, Band, Mark, Patel, Mandakini J, Medina, Audrie A, Cappello, Michael, Pekosz, Andrew, Melby, Peter C
Publicado 2014

Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azac...

por Visconte, Valeria, Nawrocki, Steffan T., Espitia, Claudia M., Kelly, Kevin R., Possemato, Anthony, Beausoleil, Sean A., Han, Yingchun, Carraway, Hetty E., Nazha, Aziz, Advani, Anjali S., Maciejewski, Jaroslaw P., Sekeres, Mikkael A., Carew, Jennifer S.
Publicado 2015