Alectinib treatment improves photodynamic therapy in cancer cell lines of different origin

por Gillissen, Bernhard, Richter, Antje, Essmann, Frank, Kemmner, Wolfgang
Publicado 2021

Simultaneous quantification of DNA damage and mitochondrial copy number by long-run DNA-damage quantification (LORD-Q)

por Dannenmann, Benjamin, Lehle, Simon, Lorscheid, Sebastian, Huber, Stephan M., Essmann, Frank, Schulze-Osthoff, Klaus
Publicado 2017

TNFα Induces Choroid Plexus Epithelial Cell Barrier Alterations by Apoptotic and Nonapoptotic Mechanisms

por Schwerk, Christian, Rybarczyk, Kasia, Essmann, Frank, Seibt, Annette, Mölleken, Marie-Louise, Zeni, Patrick, Schroten, Horst, Tenenbaum, Tobias
Publicado 2010

Direct impact of cisplatin on mitochondria induces ROS production that dictates cell fate of ovarian cancer cells

por Kleih, Markus, Böpple, Kathrin, Dong, Meng, Gaißler, Andrea, Heine, Simon, Olayioye, Monilola A., Aulitzky, Walter E., Essmann, Frank
Publicado 2019

Indolyl-chalcone derivatives trigger apoptosis in cisplatin-resistant mesothelioma cells through aberrant tubulin polymerization and deregulation of microtubule-associated proteins

por Steinlein, Sophia, Essmann, Frank, Ghilardi, Amanda Franceschini, Horn, Heike, Schüler, Julia, Hausser, Angelika, Sun, Lijun, Ott, German, Kalla, Claudia
Publicado 2023

Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis

por Gillissen, Bernhard, Essmann, Frank, Hemmati, Philipp G., Richter, Antje, Richter, Anja, Öztop, Ilker, Chinnadurai, Govindaswamy, Dörken, Bernd, Daniel, Peter T.
Publicado 2007

Contribution of BH3-domain and Transmembrane-domain to the Activity and Interaction of the Pore-forming Bcl-2 Proteins Bok, Bak, and Bax

por Stehle, Daniel, Grimm, Melanie, Einsele-Scholz, Stephanie, Ladwig, Friederike, Johänning, Janina, Fischer, Gerd, Gillissen, Bernhard, Schulze-Osthoff, Klaus, Essmann, Frank
Publicado 2018

LORD-Q: a long-run real-time PCR-based DNA-damage quantification method for nuclear and mitochondrial genome analysis

por Lehle, Simon, Hildebrand, Dominic G., Merz, Britta, Malak, Peter N., Becker, Michael S., Schmezer, Peter, Essmann, Frank, Schulze-Osthoff, Klaus, Rothfuss, Oliver
Publicado 2014

BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment

por Busche, Stephanie, John, Katharina, Wandrer, Franziska, Vondran, Florian W. R., Lehmann, Ulrich, Wedemeyer, Heiner, Essmann, Frank, Schulze-Osthoff, Klaus, Bantel, Heike
Publicado 2021

High Glutathione and Glutathione Peroxidase-2 Levels Mediate Cell-Type-Specific DNA Damage Protection in Human Induced Pluripotent Stem Cells

por Dannenmann, Benjamin, Lehle, Simon, Hildebrand, Dominic G., Kübler, Ayline, Grondona, Paula, Schmid, Vera, Holzer, Katharina, Fröschl, Mirjam, Essmann, Frank, Rothfuss, Oliver, Schulze-Osthoff, Klaus
Publicado 2015

The BCL-2 inhibitor ABT-199/venetoclax synergizes with proteasome inhibition via transactivation of the MCL-1 antagonist NOXA

por Weller, Sandra, Toennießen, Astrid, Schaefer, Benjamin, Beigl, Tobias, Muenchow, Alina, Böpple, Kathrin, Hofmann, Ute, Gillissen, Bernhard F., Aulitzky, Walter E., Kopp, Hans-Georg, Essmann, Frank
Publicado 2022

The BCL-2 selective inhibitor ABT-199 sensitizes soft tissue sarcomas to proteasome inhibition by a concerted mechanism requiring BAX and NOXA

por Muenchow, Alina, Weller, Sandra, Hinterleitner, Clemens, Malenke, Elke, Bugl, Stefanie, Wirths, Stefan, Müller, Martin R., Schulze-Osthoff, Klaus, Aulitzky, Walter E., Kopp, Hans-Georg, Essmann, Frank
Publicado 2020

Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA

por Rosa, Ilaria Dalla, Goffart, Steffi, Wurm, Melanie, Wiek, Constanze, Essmann, Frank, Sobek, Stefan, Schroeder, Peter, Zhang, Hongliang, Krutmann, Jean, Hanenberg, Helmut, Schulze-Osthoff, Klaus, Mielke, Christian, Pommier, Yves, Boege, Fritz, Christensen, Morten O.
Publicado 2009

PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy

por Fischer, Thomas, Hartmann, Oliver, Reissland, Michaela, Prieto-Garcia, Cristian, Klann, Kevin, Pahor, Nikolett, Schülein-Völk, Christina, Baluapuri, Apoorva, Polat, Bülent, Abazari, Arya, Gerhard-Hartmann, Elena, Kopp, Hans-Georg, Essmann, Frank, Rosenfeldt, Mathias, Münch, Christian, Flentje, Michael, Diefenbacher, Markus E.
Publicado 2022