Inhibition of IKKβ by celastrol and its analogues – an in silico and in vitro approach

por Veerappan, Karpagam, Natarajan, Sathishkumar, Ethiraj, Purushoth, Vetrivel, Umashankar, Samuel, Shila
Publicado 2016

MYC, mitochondrial metabolism and O-GlcNAcylation converge to modulate the activity and subcellular localization of DNA and RNA demethylases

por Lin, An-Ping, Qiu, Zhijun, Ethiraj, Purushoth, Sasi, Binu, Jaafar, Carine, Rakheja, Dinesh, Aguiar, Ricardo C. T.
Publicado 2022

Regulation of PD-L1 expression is a novel facet of cyclic-AMP-mediated immunosuppression

por Sasi, Binu, Ethiraj, Purushoth, Myers, Jamie, Lin, An-Ping, Jiang, Shoulei, Qiu, Zhijun, Holder, Kenneth N., Aguiar, Ricardo C. T.
Publicado 2020

A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions

por Estrada-Zuniga, Cynthia M., Cheng, Zi-Ming, Ethiraj, Purushoth, Guo, Qianjin, Gonzalez-Cantú, Hector, Adderley, Elaina, Lopez, Hector, Landry, Bethany N., Zainal, Abir, Aronin, Neil, Ding, Yanli, Wang, Xiaojing, Aguiar, Ricardo C.T., Dahia, Patricia L.M.
Publicado 2022

TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation

por Guo, Qianjin, Cheng, Zi-Ming, Gonzalez-Cantú, Hector, Rotondi, Matthew, Huelgas-Morales, Gabriela, Ethiraj, Purushoth, Qiu, Zhijun, Lefkowitz, Jonathan, Song, Wan, Landry, Bethany N., Lopez, Hector, Estrada-Zuniga, Cynthia M., Goyal, Shivi, Khan, Mohammad Aasif, Walker, Timothy J., Wang, Exing, Li, Faqian, Ding, Yanli, Mulligan, Lois M., Aguiar, Ricardo C.T., Dahia, Patricia L.M.
Publicado 2023