Solid-phase enzyme catalysis of DNA end repair and 3′ A-tailing reduces GC-bias in next-generation sequencing of human genomic DNA

por Zhang, Aihua, Li, Shaohua, Apone, Lynne, Sun, Xiaoli, Chen, Lixin, Ettwiller, Laurence M., Langhorst, Bradley W., Noren, Christopher J., Xu, Ming-Qun
Publicado 2018

Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base reso...

por Sun, Zhiyi, Vaisvila, Romualdas, Hussong, Laura-Madison, Yan, Bo, Baum, Chloé, Saleh, Lana, Samaranayake, Mala, Guan, Shengxi, Dai, Nan, Corrêa, Ivan R., Pradhan, Sriharsa, Davis, Theodore B., Evans, Thomas C., Ettwiller, Laurence M.
Publicado 2021