Nursing some sense out of Myc

por Sodir, Nicole M, Evan, Gerard I
Publicado 2009

Finding cancer's weakest link

por Sodir, Nicole M., Evan, Gerard I.
Publicado 2011

Inhibition of Ced-3/ICE-related Proteases Does Not Prevent Cell Death Induced by Oncogenes, DNA Damage, or the Bcl-2 Homologue Bak

por McCarthy, Nicola J., Whyte, Moira K.B., Gilbert, Christopher S., Evan, Gerard I.
Publicado 1997

The kinetics of ER fusion protein activation in vivo

por Wilson, Catherine H., Gamper, Ivonne, Perfetto, Alessandra, Auw, Jeremy, Littlewood, Trevor D., Evan, Gerard I.
Publicado 2014

The Action Mechanism of the Myc Inhibitor Termed Omomyc May Give Clues on How to Target Myc for Cancer Therapy

por Savino, Mauro, Annibali, Daniela, Carucci, Nicoletta, Favuzzi, Emilia, Cole, Michael D., Evan, Gerard I., Soucek, Laura, Nasi, Sergio
Publicado 2011

KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo

por Pekkonen, Pirita, Järviluoma, Annika, Zinovkina, Nadezhda, Cvrljevic, Anna, Prakash, Sonam, Westermarck, Jukka, Evan, Gerard I, Cesarman, Ethel, Verschuren, Emmy W, Ojala, Päivi M
Publicado 2014

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression

por Kortlever, Roderik M., Sodir, Nicole M., Wilson, Catherine H., Burkhart, Deborah L., Pellegrinet, Luca, Brown Swigart, Lamorna, Littlewood, Trevor D., Evan, Gerard I.
Publicado 2017

Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling

por Kreuzaler, Peter, Clarke, Matthew A., Brown, Elizabeth J., Wilson, Catherine H., Kortlever, Roderik M., Piterman, Nir, Littlewood, Trevor, Evan, Gerard I., Fisher, Jasmin
Publicado 2019

HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes

por Boikova, Aleksandra, Bywater, Megan J., Quaife-Ryan, Gregory A., Straube, Jasmin, Thompson, Lucy, Ascanelli, Camilla, Littlewood, Trevor D., Evan, Gerard I., Hudson, James E., Wilson, Catherine H.
Publicado 2022

Selective activation of p53-mediated tumour suppression in high-grade tumours

por Junttila, Melissa R., Karnezis, Anthony, Garcia, Daniel, Madriles, Francesc, Kortlever, Roderik M., Rostker, Fanya, Brown-Swigart, Lamorna, Pham, David M., Seo, Youngho, Evan, Gerard I., Martins, Carla P.
Publicado 2010

p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells

por Harajly, Mohamad, Zalzali, Hasan, Nawaz, Zafar, Ghayad, Sandra E., Ghamloush, Farah, Basma, Hussein, Zainedin, Samiha, Rabeh, Wissam, Jabbour, Mark, Tawil, Ayman, Badro, Danielle A., Evan, Gerard I., Saab, Raya
Publicado 2016

Determination of the physiological and pathological roles of E2F3 in adult tissues

por Gamper, Ivonne, Burkhart, Deborah L., Bywater, Megan J., Garcia, Daniel, Wilson, Catherine H., Kreuzaler, Peter A., Arends, Mark J., Zheng, Yao-Wu, Perfetto, Alessandra, Littlewood, Trevor D., Evan, Gerard I.
Publicado 2017

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution

por Sodir, Nicole M., Pellegrinet, Luca, Kortlever, Roderik M., Campos, Tania, Kwon, Yong-Won, Kim, Shinseog, Garcia, Daniel, Perfetto, Alessandra, Anastasiou, Panayiotis, Swigart, Lamorna Brown, Arends, Mark J., Littlewood, Trevor D., Evan, Gerard I.
Publicado 2022

Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity

por Bywater, Megan J., Burkhart, Deborah L., Straube, Jasmin, Sabò, Arianna, Pendino, Vera, Hudson, James E., Quaife-Ryan, Gregory A., Porrello, Enzo R., Rae, James, Parton, Robert G., Kress, Theresia R., Amati, Bruno, Littlewood, Trevor D., Evan, Gerard I., Wilson, Catherine H.
Publicado 2020

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis

por Olive, Virginie, Sabio, Erich, Bennett, Margaux J, De Jong, Caitlin S, Biton, Anne, McGann, James C, Greaney, Samantha K, Sodir, Nicole M, Zhou, Alicia Y, Balakrishnan, Asha, Foth, Mona, Luftig, Micah A, Goga, Andrei, Speed, Terence P, Xuan, Zhenyu, Evan, Gerard I, Wan, Ying, Minella, Alex C, He, Lin
Publicado 2013

Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis

por Annibali, Daniela, Whitfield, Jonathan R., Favuzzi, Emilia, Jauset, Toni, Serrano, Erika, Cuartas, Isabel, Redondo-Campos, Sara, Folch, Gerard, Gonzàlez-Juncà, Alba, Sodir, Nicole M., Massó-Vallés, Daniel, Beaulieu, Marie-Eve, Swigart, Lamorna B., Mc Gee, Margaret M., Somma, Maria Patrizia, Nasi, Sergio, Seoane, Joan, Evan, Gerard I., Soucek, Laura
Publicado 2014

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

por Lazarus, Kyren A., Hadi, Fazal, Zambon, Elisabetta, Bach, Karsten, Santolla, Maria-Francesca, Watson, Julie K., Correia, Lucia L., Das, Madhumita, Ugur, Rosemary, Pensa, Sara, Becker, Lukas, Campos, Lia S., Ladds, Graham, Liu, Pentao, Evan, Gerard I., McCaughan, Frank M., Le Quesne, John, Lee, Joo-Hyeon, Calado, Dinis, Khaled, Walid T.
Publicado 2018

The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets

por Zacarías-Fluck, Mariano F, Jauset, Toni, Martínez-Martín, Sandra, Kaur, Jastrinjan, Casacuberta-Serra, Sílvia, Massó-Vallés, Daniel, Serrano del Pozo, Erika, Martín-Fernández, Génesis, González-Larreategui, Íñigo, López-Estévez, Sergio, Brown-Swigart, Lamorna, Beaulieu, Marie-Eve, Whitfield, Jonathan R, Madan, Babita, Virshup, David M, Evan, Gerard I, Soucek, Laura
Publicado 2021

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer

por Antal, Corina E., Oh, Tae Gyu, Aigner, Stefan, Luo, En-Ching, Yee, Brian A., Campos, Tania, Tiriac, Hervé, Rothamel, Katherine L., Cheng, Zhang, Jiao, Henry, Wang, Allen, Hah, Nasun, Lenkiewicz, Elizabeth, Lumibao, Jan C., Truitt, Morgan L., Estepa, Gabriela, Banayo, Ester, Bashi, Senada, Esparza, Edgar, Munoz, Ruben M., Diedrich, Jolene K., Sodir, Nicole M., Mueller, Jasmine R., Fraser, Cory R., Borazanci, Erkut, Propper, David, Von Hoff, Daniel D., Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Han, Haiyong, Lowy, Andrew M., Barrett, Michael T., Engle, Dannielle D., Evan, Gerard I., Yeo, Gene W., Downes, Michael, Evans, Ronald M.
Publicado 2023

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

por Abbosh, Christopher, Frankell, Alexander M., Harrison, Thomas, Kisistok, Judit, Garnett, Aaron, Johnson, Laura, Veeriah, Selvaraju, Moreau, Mike, Chesh, Adrian, Chaunzwa, Tafadzwa L., Weiss, Jakob, Schroeder, Morgan R., Ward, Sophia, Grigoriadis, Kristiana, Shahpurwalla, Aamir, Litchfield, Kevin, Puttick, Clare, Biswas, Dhruva, Karasaki, Takahiro, Black, James R. M., Martínez-Ruiz, Carlos, Al Bakir, Maise, Pich, Oriol, Watkins, Thomas B. K., Lim, Emilia L., Huebner, Ariana, Moore, David A., Godin-Heymann, Nadia, L'Hernault, Anne, Bye, Hannah, Odell, Aaron, Roberts, Paula, Gomes, Fabio, Patel, Akshay J., Manzano, Elizabeth, Hiley, Crispin T., Carey, Nicolas, Riley, Joan, Cook, Daniel E., Hodgson, Darren, Stetson, Daniel, Barrett, J. Carl, Kortlever, Roderik M., Evan, Gerard I., Hackshaw, Allan, Daber, Robert D., Shaw, Jacqui A., Aerts, Hugo J.W.L., Licon, Abel, Stahl, Josh, Jamal-Hanjani, Mariam, Birkbak, Nicolai J, McGranahan, Nicholas, Swanton, Charles
Publicado 2023