Improving the treatment of childhood acute lymphoblastic leukemia by optimizing the use of 70-year-old drugs

por Evans, William E.
Publicado 2021

CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor

por Zou, Chan, Beard, Jordan A, Yang, Guoping, Evans, William E, Bonten, Erik J
Publicado 2022

Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells

por Panetta, John C., Sparreboom, Alex, Pui, Ching-Hon, Relling, Mary V., Evans, William E.
Publicado 2010

Bayesian modelling of response to therapy and drug-sensitivity in acute lymphoblastic leukemia

por Cremaschi, Andrea, Yang, Wenjian, De Iorio, Maria, Evans, William E., Yang, Jun J., Rosner, Gary L.
Publicado 2023

PACSIN2 as a modulator of autophagy and mercaptopurine cytotoxicity: mechanisms in lymphoid and intestinal cells

por Zudeh, Giulia, Franca, Raffaella, Lucafò, Marianna, Bonten, Erik J, Bramuzzo, Matteo, Sgarra, Riccardo, Lagatolla, Cristina, Franzin, Martina, Evans, William E, Decorti, Giuliana, Stocco, Gabriele
Publicado 2023

Concordant Gene Expression in Leukemia Cells and Normal Leukocytes Is Associated with Germline cis-SNPs

por French, Deborah, Yang, Wenjian, Hamilton, Leo H., Neale, Geoffrey, Fan, Yiping, Downing, James R., Cox, Nancy J., Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2008

Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells

por Bakke, Jesse, Wright, William C., Zamora, Anthony E., Oladimeji, Peter, Crawford, Jeremy Chase, Brewer, Christopher T., Autry, Robert J., Evans, William E., Thomas, Paul G., Chen, Taosheng
Publicado 2019

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models

por Karol, Seth E., Janke, Laura J., Panetta, John C., Ramsey, Laura B., Cai, Xiangjun, Payton, Monique A., Jenkins, David A., Evans, William E., Relling, Mary V.
Publicado 2019

Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice

por Diouf, Barthelemy, Devaraju, Prakash, Janke, Laura J., Fan, Yiping, Frase, Sharon, Eddins, Donnie, Peters, Jennifer L., Kim, Jieun, Pei, Deqing, Cheng, Cheng, Zakharenko, Stanislav S., Evans, William E.
Publicado 2016

Fluoroquinolone prophylaxis does not increase risk of neuropathy in children with acute lymphoblastic leukemia

por Karol, Seth E., Sun, Yilun, Tang, Li, Pui, Ching‐Hon, Ferrolino, Jose, Allison, Kim J., Cross, Shane J., Evans, William E., Crews, Kristine R., Jeha, Sima, Wolf, Joshua
Publicado 2020

In Vivo Response to Methotrexate Forecasts Outcome of Acute Lymphoblastic Leukemia and Has a Distinct Gene Expression Profile

por Sorich, Michael J, Pottier, Nicolas, Pei, Deqing, Yang, Wenjian, Kager, Leo, Stocco, Gabriele, Cheng, Cheng, Panetta, John C, Pui, Ching-Hon, Relling, Mary V, Cheok, Meyling H, Evans, William E
Publicado 2008

A p53-regulated apoptotic gene signature predicts treatment response and outcome in pediatric acute lymphoblastic leukemia

por Bainer, Russell O, Trendowski, Matthew R, Cheng, Cheng, Pei, Deqing, Yang, Wenjian, Paugh, Steven W, Goss, Kathleen H, Skol, Andrew D, Pavlidis, Paul, Pui, Ching-Hon, Gilliam, T Conrad, Evans, William E, Onel, Kenan
Publicado 2017

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

por Ramsey, Laura B., Janke, Laura J., Payton, Monique A., Cai, Xiangjun, Paugh, Steven W., Karol, Seth E., Kamdem, Landry Kamdem, Cheng, Cheng, Williams, Richard T., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2015

Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments

por Pauley, Jennifer L., Panetta, John C., Crews, Kristine R., Pei, Deqing, Cheng, Cheng, McCormick, John, Howard, Scott C., Sandlund, John T., Jeha, Sima, Ribeiro, Raul, Rubnitz, Jeffrey, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2013

Erratum to: Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments

por Pauley, Jennifer L., Panetta, John C., Crews, Kristine R., Pei, Deqing, Cheng, Cheng, McCormick, John, Howard, Scott C., Sandlund, John T., Jeha, Sima, Ribeiro, Raul, Rubnitz, Jeffrey, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2013

Association between CEP72 genotype and persistent neuropathy in survivors of childhood acute lymphoblastic leukemia

por Goodenough, Chelsea G., Diouf, Barthelemy, Yang, Wenjian, Sapkota, Yadav, Finch, Emily R., Lu, Lu, Partin, Robyn E., Wogksch, Matthew D., Hudson, Melissa M., Robison, Leslie L., Wang, Zhaoming, Jeha, Sima, Evans, William E., Ness, Kirsten K.
Publicado 2022

Development and use of active clinical decision support for preemptive pharmacogenomics

por Bell, Gillian C, Crews, Kristine R, Wilkinson, Mark R, Haidar, Cyrine E, Hicks, J Kevin, Baker, Donald K, Kornegay, Nancy M, Yang, Wenjian, Cross, Shane J, Howard, Scott C, Freimuth, Robert R, Evans, William E, Broeckel, Ulrich, Relling, Mary V, Hoffman, James M
Publicado 2014

Multiplex Assessment of Protein Variant Abundance by Massively Parallel Sequencing

por Matreyek, Kenneth A., Starita, Lea M., Stephany, Jason J., Martin, Beth, Chiasson, Melissa A., Gray, Vanessa E., Kircher, Martin, Khechaduri, Arineh, Dines, Jennifer N., Hause, Ronald J., Bhatia, Smita, Evans, William E., Relling, Mary V., Yang, Wenjian, Shendure, Jay, Fowler, Douglas M.
Publicado 2018

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells

por Diouf, Barthelemy, Cheng, Qing, Krynetskaia, Natalia F., Yang, Wenjian, Cheok, Meyling, Pei, Deqing, Fan, Yiping, Cheng, Cheng, Krynetskiy, Evgeny Y., Geng, Hui, Chen, Siying, Thierfelder, William E., Mullighan, Charles G., Downing, James R., Hsieh, Peggy, Pui, Ching-Hon, Relling, Mary V., Evans, William E.
Publicado 2011

Relapse specific mutations in NT5C2 in childhood acute lymphoblastic leukemia

por Meyer, Julia A., Wang, Jinhua, Hogan, Laura E., Yang, Jun J., Dandekar, Smita, Patel, Jay P., Tang, Zuojian, Zumbo, Paul, Li, Sheng, Zavadil, Jiri, Levine, Ross L., Cardozo, Timothy, Hunger, Stephen P., Raetz, Elizabeth A., Evans, William E., Morrison, Debra J., Mason, Christopher E., Carroll, William L.
Publicado 2013