A fluorescence-based high throughput-screening assay for the SARS-CoV RNA synthesis complex

por Eydoux, Cecilia, Fattorini, Veronique, Shannon, Ashleigh, Le, Thi-Tuyet-Nhung, Didier, Bruno, Canard, Bruno, Guillemot, Jean-Claude
Publicado 2021

Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites

por Shannon, Ashleigh, Le, Nhung Thi-Tuyet, Selisko, Barbara, Eydoux, Cecilia, Alvarez, Karine, Guillemot, Jean-Claude, Decroly, Etienne, Peersen, Olve, Ferron, Francois, Canard, Bruno
Publicado 2020

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

por Aouadi, Wahiba, Eydoux, Cécilia, Coutard, Bruno, Martin, Baptiste, Debart, Françoise, Vasseur, Jean Jacques, Contreras, Jean Marie, Morice, Christophe, Quérat, Gilles, Jung, Marie-Louise, Canard, Bruno, Guillemot, Jean-Claude, Decroly, Etienne
Publicado 2017

A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro

por De Castro, Sonia, Stevaert, Annelies, Maldonado, Miguel, Delpal, Adrien, Vandeput, Julie, Van Loy, Benjamin, Eydoux, Cecilia, Guillemot, Jean-Claude, Decroly, Etienne, Gago, Federico, Canard, Bruno, Camarasa, Maria-Jose, Velázquez, Sonsoles, Naesens, Lieve
Publicado 2022

System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2

por Vicenti, Ilaria, Martina, Maria Grazia, Boccuto, Adele, De Angelis, Marta, Giavarini, Giorgia, Dragoni, Filippo, Marchi, Serena, Trombetta, Claudia Maria, Crespan, Emmanuele, Maga, Giovanni, Eydoux, Cecilia, Decroly, Etienne, Montomoli, Emanuele, Nencioni, Lucia, Zazzi, Maurizio, Radi, Marco
Publicado 2021

A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

por Shannon, Ashleigh, Fattorini, Véronique, Sama, Bhawna, Selisko, Barbara, Feracci, Mikael, Falcou, Camille, Gauffre, Pierre, El Kazzi, Priscila, Delpal, Adrien, Decroly, Etienne, Alvarez, Karine, Eydoux, Cécilia, Guillemot, Jean-Claude, Moussa, Adel, Good, Steven S., La Colla, Paolo, Lin, Kai, Sommadossi, Jean-Pierre, Zhu, Yingxiao, Yan, Xiaodong, Shi, Hui, Ferron, François, Canard, Bruno
Publicado 2022

Synthesis, Structure–Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication

por Bardiot, Dorothée, Vangeel, Laura, Koukni, Mohamed, Arzel, Philippe, Zwaagstra, Marleen, Lyoo, Heyrhyoung, Wanningen, Patrick, Ahmad, Shamshad, Zhang, Linlin, Sun, Xinyuanyuan, Delpal, Adrien, Eydoux, Cecilia, Guillemot, Jean-Claude, Lescrinier, Eveline, Klaassen, Hugo, Leyssen, Pieter, Jochmans, Dirk, Castermans, Karolien, Hilgenfeld, Rolf, Robinson, Colin, Decroly, Etienne, Canard, Bruno, Snijder, Eric J., van Hemert, Martijn J., van Kuppeveld, Frank, Chaltin, Patrick, Neyts, Johan, De Jonghe, Steven, Marchand, Arnaud
Publicado 2022

Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir

por Lo, Ho Sing, Hui, Kenrie Pui Yan, Lai, Hei-Ming, He, Xu, Khan, Khadija Shahed, Kaur, Simranjeet, Huang, Junzhe, Li, Zhongqi, Chan, Anthony K. N., Cheung, Hayley Hei-Yin, Ng, Ka-Chun, Ho, John Chi Wang, Chen, Yu Wai, Ma, Bowen, Cheung, Peter Man-Hin, Shin, Donghyuk, Wang, Kaidao, Lee, Meng-Hsuan, Selisko, Barbara, Eydoux, Cecilia, Guillemot, Jean-Claude, Canard, Bruno, Wu, Kuen-Phon, Liang, Po-Huang, Dikic, Ivan, Zuo, Zhong, Chan, Francis K. L., Hui, David S. C., Mok, Vincent C. T., Wong, Kam-Bo, Mok, Chris Ka Pun, Ko, Ho, Aik, Wei Shen, Chan, Michael Chi Wai, Ng, Wai-Lung
Publicado 2021