The Histone Methyltransferase MMSET/WHSC1 Activates TWIST1 to Promote an Epithelial-Mesenchymal Transition and Invasive Properties of Prostate Cancer

por Ezponda, Teresa, Popovic, Relja, Shah, Mrinal Y., Martinez-Garcia, Eva, Zheng, Yupeng, Min, Dong-Joon, Will, Christine, Neri, Antonino, Kelleher, Neil L., Yu, Jindan, Licht, Jonathan D.
Publicado 2012

SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

por Peng, Jianhao, Serrano, Guillermo, Traniello, Ian M., Calleja-Cervantes, Maria E., Chembazhi, Ullas V., Bangru, Sushant, Ezponda, Teresa, Rodriguez-Madoz, Juan Roberto, Kalsotra, Auinash, Prosper, Felipe, Ochoa, Idoia, Hernaez, Mikel
Publicado 2022

Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells

por Garitano-Trojaola, Andoni, José-Enériz, Edurne San, Ezponda, Teresa, Unfried, Juan Pablo, Carrasco-León, Arantxa, Razquin, Nerea, Barriocanal, Marina, Vilas-Zornoza, Amaia, Sangro, Bruno, Segura, Victor, Prósper, Felipe, Fortes, Puri, Agirre, Xabier
Publicado 2018

MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents

por Shah, Mrinal Y., Martinez-Garcia, Eva, Phillip, Jude M., Chambliss, Allison B., Popovic, Relja, Ezponda, Teresa, Small, Eliza C., Will, Christine, Phillip, Madonna P., Neri, Paola, Bahlis, Nizar J., Wirtz, Denis, Licht, Jonathan D.
Publicado 2016

MMSET dysregulates gene expression in myeloma through global and focal changes in H3K36 and H3K27 methylation

por Popovic, Relja, Martinez-Garcia, Eva, Zhang, Quanwei, Ezponda, Teresa, Shah, Mrinal Y, Zhang, Yupeng, Jiang, Yanwen, Will, Christine M, Small, Eliza C, Bulic, Marinka, Elemento, Olivier, Kelleher, Neil, Kath, William, Wang, Ji-Ping, Licht, Jonathan D
Publicado 2013

Development of a novel splice array platform and its application in the identification of alternative splice variants in lung cancer

por Pio, Ruben, Blanco, David, Pajares, Maria Jose, Aibar, Elena, Durany, Olga, Ezponda, Teresa, Agorreta, Jackeline, Gomez-Roman, Javier, Anton, Miguel Angel, Rubio, Angel, Lozano, Maria D, López-Picazo, Jose M, Subirada, Francesc, Maes, Tamara, Montuenga, Luis M
Publicado 2010

Germline ERCC excision repair 6 like 2 ( ERCC6L2 ) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment

por Armes, Hannah, Bewicke‐Copley, Findlay, Rio‐Machin, Ana, Di Bella, Doriana, Philippe, Céline, Wozniak, Anna, Tummala, Hemanth, Wang, Jun, Ezponda, Teresa, Prosper, Felipe, Dokal, Inderjeet, Vulliamy, Tom, Kilpivaara, Outi, Wartiovaara‐Kautto, Ulla, Fitzgibbon, Jude, Rouault‐Pierre, Kevin
Publicado 2022

Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation

por Popovic, Relja, Martinez-Garcia, Eva, Giannopoulou, Eugenia G., Zhang, Quanwei, Zhang, Qingyang, Ezponda, Teresa, Shah, Mrinal Y., Zheng, Yupeng, Will, Christine M., Small, Eliza C., Hua, Youjia, Bulic, Marinka, Jiang, Yanwen, Carrara, Matteo, Calogero, Raffaele A., Kath, William L., Kelleher, Neil L., Wang, Ji-Ping, Elemento, Olivier, Licht, Jonathan D.
Publicado 2014

Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution

por Ainciburu, Marina, Ezponda, Teresa, Berastegui, Nerea, Alfonso-Pierola, Ana, Vilas-Zornoza, Amaia, San Martin-Uriz, Patxi, Alignani, Diego, Lamo-Espinosa, Jose, San-Julian, Mikel, Jiménez-Solas, Tamara, Lopez, Felix, Muntion, Sandra, Sanchez-Guijo, Fermin, Molero, Antonieta, Montoro, Julia, Serrano, Guillermo, Diaz-Mazkiaran, Aintzane, Lasaga, Miren, Gomez-Cabrero, David, Diez-Campelo, Maria, Valcarcel, David, Hernaez, Mikel, Romero, Juan P, Prosper, Felipe
Publicado 2023

Characterization of complete lncRNAs transcriptome reveals the functional and clinical impact of lncRNAs in multiple myeloma

por Carrasco-Leon, Arantxa, Ezponda, Teresa, Meydan, Cem, Valcárcel, Luis V., Ordoñez, Raquel, Kulis, Marta, Garate, Leire, Miranda, Estíbaliz, Segura, Victor, Guruceaga, Elisabeth, Vilas-Zornoza, Amaia, Alignani, Diego, Pascual, Marién, Amundarain, Ane, Castro-Labrador, Laura, Martín-Uriz, Patxi San, El-Omri, Halima, Taha, Ruba Y., Calasanz, Maria J., Planes, Francisco J., Paiva, Bruno, Mason, Christopher E., San Miguel, Jesús F., Martin-Subero, José I., Melnick, Ari, Prosper, Felipe, Agirre, Xabier
Publicado 2021

The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes

por Berastegui, Nerea, Ainciburu, Marina, Romero, Juan P., Garcia-Olloqui, Paula, Alfonso-Pierola, Ana, Philippe, Céline, Vilas-Zornoza, Amaia, San Martin-Uriz, Patxi, Ruiz-Hernández, Raquel, Abarrategi, Ander, Ordoñez, Raquel, Alignani, Diego, Sarvide, Sarai, Castro-Labrador, Laura, Lamo-Espinosa, José M., San-Julian, Mikel, Jimenez, Tamara, López-Cadenas, Félix, Muntion, Sandra, Sanchez-Guijo, Fermin, Molero, Antonieta, Montoro, Maria Julia, Tazón, Bárbara, Serrano, Guillermo, Diaz-Mazkiaran, Aintzane, Hernaez, Mikel, Huerga, Sofía, Bewicke-Copley, Findlay, Rio-Machin, Ana, Maurano, Matthew T., Díez-Campelo, María, Valcarcel, David, Rouault-Pierre, Kevin, Lara-Astiaso, David, Ezponda, Teresa, Prosper, Felipe
Publicado 2022

Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

por Ordoñez, Raquel, Kulis, Marta, Russiñol, Nuria, Chapaprieta, Vicente, Carrasco-Leon, Arantxa, García-Torre, Beatriz, Charalampopoulou, Stella, Clot, Guillem, Beekman, Renée, Meydan, Cem, Duran-Ferrer, Martí, Verdaguer-Dot, Núria, Vilarrasa-Blasi, Roser, Soler-Vila, Paula, Garate, Leire, Miranda, Estíbaliz, San José-Enériz, Edurne, Rodriguez-Madoz, Juan R., Ezponda, Teresa, Martínez-Turrilas, Rebeca, Vilas-Zornoza, Amaia, Lara-Astiaso, David, Dupéré-Richer, Daphné, Martens, Joost H.A., El-Omri, Halima, Taha, Ruba Y., Calasanz, Maria J., Paiva, Bruno, San Miguel, Jesus, Flicek, Paul, Gut, Ivo, Melnick, Ari, Mitsiades, Constantine S., Licht, Jonathan D., Campo, Elias, Stunnenberg, Hendrik G., Agirre, Xabier, Prosper, Felipe, Martin-Subero, Jose I.
Publicado 2020