Filamin-A-interacting protein 1 (FILIP1) is a dual compartment protein linking myofibrils and microtubules during myogenic differentiation and upon mechanical stress

por Grande, Valentina, Schuld, Julia, van der Ven, Peter F. M., Gruss, Oliver J., Fürst, Dieter O.
Publicado 2023

Breaking sarcomeres by in vitro exercise

por Orfanos, Zacharias, Gödderz, Markus P. O., Soroka, Ekaterina, Gödderz, Tobias, Rumyantseva, Anastasia, van der Ven, Peter F. M., Hawke, Thomas J., Fürst, Dieter O.
Publicado 2016

Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function

por Unger, Andreas, Beckendorf, Lisa, Böhme, Pierre, Kley, Rudolf, von Frieling-Salewsky, Marion, Lochmüller, Hanns, Schröder, Rolf, Fürst, Dieter O., Vorgerd, Matthias, Linke, Wolfgang A.
Publicado 2017

Indications for a Novel Muscular Dystrophy Pathway: γ-Filamin, the Muscle-Specific Filamin Isoform, Interacts with Myotilin

por van der Ven, Peter F.M., Wiesner, Sebastian, Salmikangas, Paula, Auerbach, Daniel, Himmel, Mirko, Kempa, Stefan, Hayeß, Katrin, Pacholsky, Dirk, Taivainen, Anu, Schröder, Rolf, Carpén, Olli, Fürst, Dieter O.
Publicado 2000

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis

por Görtzen, Jan, Schierwagen, Robert, Bierwolf, Jeanette, Klein, Sabine, Uschner, Frank E., van der Ven, Peter F., Fürst, Dieter O., Strassburg, Christian P., Laleman, Wim, Pollok, Jörg-Matthias, Trebicka, Jonel
Publicado 2015

Xirp Proteins Mark Injured Skeletal Muscle in Zebrafish

por Otten, Cécile, van der Ven, Peter F., Lewrenz, Ilka, Paul, Sandeep, Steinhagen, Almut, Busch-Nentwich, Elisabeth, Eichhorst, Jenny, Wiesner, Burkhard, Stemple, Derek, Strähle, Uwe, Fürst, Dieter O., Abdelilah-Seyfried, Salim
Publicado 2012

Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats

por Klein, Sabine, Frohn, Franziska, Magdaleno, Fernando, Reker-Smit, Catharina, Schierwagen, Robert, Schierwagen, Irela, Uschner, Frank Erhard, van Dijk, Fransien, Fürst, Dieter O., Djudjaj, Sonja, Boor, Peter, Poelstra, Klaas, Beljaars, Leonie, Trebicka, Jonel
Publicado 2019

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling

por Eulitz, Stefan, Sauer, Florian, Pelissier, Marie-Cecile, Boisguerin, Prisca, Molt, Sibylle, Schuld, Julia, Orfanos, Zacharias, Kley, Rudolf A., Volkmer, Rudolf, Wilmanns, Matthias, Kirfel, Gregor, van der Ven, Peter F. M., Fürst, Dieter O.
Publicado 2013

Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation

por Schuld, Julia, Orfanos, Zacharias, Chevessier, Frédéric, Eggers, Britta, Heil, Lorena, Uszkoreit, Julian, Unger, Andreas, Kirfel, Gregor, van der Ven, Peter F. M., Marcus, Katrin, Linke, Wolfgang A., Clemen, Christoph S., Schröder, Rolf, Fürst, Dieter O.
Publicado 2020

Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertensio...

por Uschner, Frank E., Ranabhat, Ganesh, Choi, Steve S., Granzow, Michaela, Klein, Sabine, Schierwagen, Robert, Raskopf, Esther, Gautsch, Sebastian, van der Ven, Peter F. M., Fürst, Dieter O., Strassburg, Christian P., Sauerbruch, Tilman, Mae Diehl, Anna, Trebicka, Jonel
Publicado 2015

Maintaining proteostasis under mechanical stress

por Höhfeld, Jörg, Benzing, Thomas, Bloch, Wilhelm, Fürst, Dieter O, Gehlert, Sebastian, Hesse, Michael, Hoffmann, Bernd, Hoppe, Thorsten, Huesgen, Pitter F, Köhn, Maja, Kolanus, Waldemar, Merkel, Rudolf, Niessen, Carien M, Pokrzywa, Wojciech, Rinschen, Markus M, Wachten, Dagmar, Warscheid, Bettina
Publicado 2021

Novel Filamin C Myofibrillar Myopathy Variants Cause Different Pathomechanisms and Alterations in Protein Quality Systems

por Sellung, Dominik, Heil, Lorena, Daya, Nassam, Jacobsen, Frank, Mertens-Rill, Janine, Zhuge, Heidi, Döring, Kristina, Piran, Misagh, Milting, Hendrik, Unger, Andreas, Linke, Wolfgang A., Kley, Rudi, Preusse, Corinna, Roos, Andreas, Fürst, Dieter O., van der Ven, Peter F. M., Vorgerd, Matthias
Publicado 2023

Molecular basis of F-actin regulation and sarcomere assembly via myotilin

por Kostan, Julius, Pavšič, Miha, Puž, Vid, Schwarz, Thomas C., Drepper, Friedel, Molt, Sibylle, Graewert, Melissa Ann, Schreiner, Claudia, Sajko, Sara, van der Ven, Peter F. M., Onipe, Adekunle, Svergun, Dmitri I., Warscheid, Bettina, Konrat, Robert, Fürst, Dieter O., Lenarčič, Brigita, Djinović-Carugo, Kristina
Publicado 2021

FLNC-Associated Myofibrillar Myopathy: New Clinical, Functional, and Proteomic Data

por Kley, Rudolf Andre, Leber, Yvonne, Schrank, Bertold, Zhuge, Heidi, Orfanos, Zacharias, Kostan, Julius, Onipe, Adekunle, Sellung, Dominik, Güttsches, Anne Katrin, Eggers, Britta, Jacobsen, Frank, Kress, Wolfram, Marcus, Katrin, Djinovic-Carugo, Kristina, van der Ven, Peter F.M., Fürst, Dieter O., Vorgerd, Matthias
Publicado 2021

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C

por Collier, Miranda P., Alderson, T. Reid, de Villiers, Carin P., Nicholls, Daisy, Gastall, Heidi Y., Allison, Timothy M., Degiacomi, Matteo T., Jiang, He, Mlynek, Georg, Fürst, Dieter O., van der Ven, Peter F. M., Djinovic-Carugo, Kristina, Baldwin, Andrew J., Watkins, Hugh, Gehmlich, Katja, Benesch, Justin L. P.
Publicado 2019

Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C

por Reimann, Lena, Schwäble, Anja N., Fricke, Anna L., Mühlhäuser, Wignand W. D., Leber, Yvonne, Lohanadan, Keerthika, Puchinger, Martin G., Schäuble, Sascha, Faessler, Erik, Wiese, Heike, Reichenbach, Christa, Knapp, Bettina, Peikert, Christian D., Drepper, Friedel, Hahn, Udo, Kreutz, Clemens, van der Ven, Peter F. M., Radziwill, Gerald, Djinović-Carugo, Kristina, Fürst, Dieter O., Warscheid, Bettina
Publicado 2020

Overexpression of human BAG3(P209L) in mice causes restrictive cardiomyopathy

por Kimura, Kenichi, Ooms, Astrid, Graf-Riesen, Kathrin, Kuppusamy, Maithreyan, Unger, Andreas, Schuld, Julia, Daerr, Jan, Lother, Achim, Geisen, Caroline, Hein, Lutz, Takahashi, Satoru, Li, Guang, Röll, Wilhelm, Bloch, Wilhelm, van der Ven, Peter F. M., Linke, Wolfgang A., Wu, Sean M., Huesgen, Pitter F., Höhfeld, Jörg, Fürst, Dieter O., Fleischmann, Bernd K., Hesse, Michael
Publicado 2021

Recessive Mutations in SYNPO2 as a Candidate of Monogenic Nephrotic Syndrome

por Mao, Youying, Schneider, Ronen, van der Ven, Peter F.M., Assent, Marvin, Lohanadan, Keerthika, Klämbt, Verena, Buerger, Florian, Kitzler, Thomas M., Deutsch, Konstantin, Nakayama, Makiko, Majmundar, Amar J., Mann, Nina, Hermle, Tobias, Onuchic-Whitford, Ana C., Zhou, Wei, Margam, Nandini Nagarajan, Duncan, Roy, Marquez, Jonathan, Khokha, Mustafa, Fathy, Hanan M., Kari, Jameela A., El Desoky, Sherif, Eid, Loai A., Awad, Hazem Subhi, Al-Saffar, Muna, Mane, Shrikant, Lifton, Richard P., Fürst, Dieter O., Shril, Shirlee, Hildebrandt, Friedhelm
Publicado 2020