Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines

por Nowotarski, Shannon L, Feith, David J, Shantz, Lisa M
Publicado 2015

LGL leukemia patients exhibit substantial protective humoral responses following SARS‐CoV‐2 vaccination

por Cheon, Heejin, Elghawy, Omar, Shemo, Bryna C., Feith, David J., Loughran, Thomas P.
Publicado 2022

Emergence of a STAT3 mutated NK clone in LGL leukemia

por Yan, Yiyi, Olson, Thomas L., Nyland, Susan B., Feith, David J., Loughran, Thomas P.
Publicado 2014

Intersection Between Large Granular Lymphocyte Leukemia and Rheumatoid Arthritis

por Moosic, Katharine B., Ananth, Kusuma, Andrade, Felipe, Feith, David J., Darrah, Erika, Loughran, Thomas P.
Publicado 2022

DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27(Kip1) activity in neuroblastoma

por KOOMOA, DANA-LYNN T., GEERTS, DIRK, LANGE, INGO, KOSTER, JAN, PEGG, ANTHONY E., FEITH, DAVID J., BACHMANN, ANDRÉ S.
Publicado 2013

Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes

por Steinway, Steven Nathaniel, Zañudo, Jorge Gomez Tejeda, Michel, Paul J, Feith, David J, Loughran, Thomas P, Albert, Reka
Publicado 2015

Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia

por Kulling, Paige M., Olson, Kristine C., Hamele, Cait E., Toro, Mariella F., Tan, Su-Fern, Feith, David J., Loughran, Thomas P.
Publicado 2018

Retrovirus insertion site analysis of LGL leukemia patient genomes

por Li, Weiling, Yang, Lei, Harris, Robert S., Lin, Lin, Olson, Thomas L., Hamele, Cait E., Feith, David J., Loughran, Thomas P., Poss, Mary
Publicado 2019

Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation

por Wang, T. Tiffany, Yang, Jun, Dighe, Shubha, Schmachtenberg, Matthew W., Leigh, Nathan T., Farber, Emily, Onengut-Gumuscu, Suna, Feith, David J., Ratan, Aakrosh, Loughran, Thomas P., Olson, Thomas L.
Publicado 2020

Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations

por Olson, Kristine C., Moosic, Katharine B., Jones, Marieke K., Larkin, Paige M. K., Olson, Thomas L., Toro, Mariella F., Fox, Todd E., Feith, David J., Loughran, Thomas P.
Publicado 2020

The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia

por Annageldiyev, Charyguly, Gowda, Krishne, Patel, Trupti, Bhattacharya, Priyanjali, Tan, Su-Fern, Iyer, Soumya, Desai, Dhimant, Dovat, Sinisa, Feith, David J., Loughran, Thomas P., Amin, Shantu, Claxton, David, Sharma, Arati
Publicado 2020

IL-2 and IL-15 blockade by BNZ-1, an inhibitor of selective γ-chain cytokines, decreases leukemic T-cell viability

por Wang, T. Tiffany, Yang, Jun, Zhang, Yong, Zhang, Meili, Dubois, Sigrid, Conlon, Kevin C., Tagaya, Yutaka, Hamele, Cait E., Dighe, Shubha, Olson, Thomas L., Feith, David J., Azimi, Nazli, Waldmann, Thomas A., Loughran, Thomas P.
Publicado 2018

miR-181a is a novel player in the STAT3-mediated survival network of TCRαβ+ CD8+ T large granular lymphocyte leukemia

por Assmann, Jorn L. J. C., Leon, Leticia G., Stavast, Christiaan J., van den Bogaerdt, Sanne E., Schilperoord-Vermeulen, Joyce, Sandberg, Yorick, Bellido, Mar, Erkeland, Stefan J., Feith, David J., Loughran Jr, Thomas P., Langerak, Anton W.
Publicado 2021

C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia

por Ryland, Lindsay K., Doshi, Ushma A., Shanmugavelandy, Sriram S., Fox, Todd E., Aliaga, Cesar, Broeg, Kathleen, Baab, Kendall Thomas, Young, Megan, Khan, Osman, Haakenson, Jeremy K., Jarbadan, Nancy Ruth, Liao, Jason, Wang, Hong-Gang, Feith, David J., Loughran Jr, Thomas P., Liu, Xin, Kester, Mark
Publicado 2013

The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia

por Annageldiyev, Charyguly, Tan, Su-Fern, Thakur, Shreya, Dhanyamraju, Pavan Kumar, Ramisetti, Srinivasa R., Bhadauria, Preeti, Schick, Jacob, Zeng, Zheng, Sharma, Varun, Dunton, Wendy, Dovat, Sinisa, Desai, Dhimant, Zheng, Hong, Feith, David J., Loughran, Thomas P., Amin, Shantu, Sharma, Arun K., Claxton, David, Sharma, Arati
Publicado 2020

Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia

por Khokhlatchev, Andrei V., Sharma, Arati, Deering, Tye G., Shaw, Jeremy J. P., Costa‐Pinheiro, Pedro, Golla, Upendarrao, Annageldiyev, Charyguly, Cabot, Myles C., Conaway, Mark R., Tan, Su‐Fern, Ung, Johnson, Feith, David J., Loughran, Thomas P., Claxton, David F., Fox, Todd E., Kester, Mark
Publicado 2022

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

por Paudel, B. Bishal, Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Shaw, Jeremy, Dunton, Wendy, Lee, Irene, Sharma, Arati, Viny, Aaron D., Barth, Brian M., Tallman, Martin S., Cabot, Myles, Garrett-Bakelman, Francine E., Levine, Ross L., Kester, Mark, Claxton, David, Feith, David J., Janes, Kevin A., Loughran, Thomas P.
Publicado 2023

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloi...

por Fisher-Wellman, Kelsey H., Kassai, Miki, Hagen, James T., Neufer, P. Darrell, Kester, Mark, Loughran, Thomas P., Chalfant, Charles E., Feith, David J., Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Fabrias, Gemma, Abad, Jose’ Luis, Sharma, Arati, Golla, Upendarrao, Claxton, David F., Shaw, Jeremy J. P., Bhowmick, Debajit, Cabot, Myles C.
Publicado 2023

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

por Tan, Su-Fern, Liu, Xin, Fox, Todd E., Barth, Brian M., Sharma, Arati, Turner, Stephen D., Awwad, Andy, Dewey, Alden, Doi, Kenichiro, Spitzer, Barbara, Shah, Mithun Vinod, Morad, Samy A.F., Desai, Dhimant, Amin, Shantu, Zhu, Junjia, Liao, Jason, Yun, Jong, Kester, Mark, Claxton, David F., Wang, Hong-Gang, Cabot, Myles C., Schuchman, Edward H., Levine, Ross L., Feith, David J., Loughran, Thomas P.
Publicado 2016

CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk

por Baer, Constance, Kimura, Shunsuke, Rana, Mitra S., Kleist, Andrew B., Flerlage, Tim, Feith, David J., Chockley, Peter, Walter, Wencke, Meggendorfer, Manja, Olson, Thomas L., Cheon, HeeJin, Olson, Kristine C., Ratan, Aakrosh, Mueller, Martha-Lena, Foran, James M., Janke, Laura J., Qu, Chunxu, Porter, Shaina N., Pruett-Miller, Shondra M., Kalathur, Ravi C., Haferlach, Claudia, Kern, Wolfgang, Paietta, Elisabeth, Thomas, Paul G., Babu, M. Madan, Loughran, Thomas P., Iacobucci, Ilaria, Haferlach, Torsten, Mullighan, Charles G
Publicado 2022