Protocol for isolating human BCAM-positive corneal progenitor cells by flow cytometry and cell sorting

por Sasamoto, Yuzuru, Yeung, Philip C., Tran, Johnathan, Frank, Markus H., Frank, Natasha Y.
Publicado 2023

Skin-Derived ABCB5(+) Mesenchymal Stem Cells for High-Medical-Need Inflammatory Diseases: From Discovery to Entering Clinical Routine

por Niebergall-Roth, Elke, Frank, Natasha Y., Ganss, Christoph, Frank, Markus H., Kluth, Mark A.
Publicado 2022

High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells

por Sasamoto, Yuzuru, Lee, Catherine A.A., Yoshihara, Masahito, Martin, Gabrielle, Ksander, Bruce R., Frank, Markus H., Frank, Natasha Y.
Publicado 2022

Epigenetic Regulation of Corneal Epithelial Differentiation by TET2

por Sasamoto, Yuzuru, Wu, Siyuan, Lee, Catherine A. A., Jiang, Jason Y., Ksander, Bruce R., Frank, Markus H., Frank, Natasha Y.
Publicado 2023

Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities

por Watanabe, Shinya, Hayashi, Ryuhei, Sasamoto, Yuzuru, Tsujikawa, Motokazu, Ksander, Bruce R., Frank, Markus H., Quantock, Andrew J., Frank, Natasha Y., Nishida, Kohji
Publicado 2021

Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin

por Frank, Natasha Y., Kho, Alvin T., Schatton, Tobias, Murphy, George F., Molloy, Michael J., Zhan, Qian, Ramoni, Marco F., Frank, Markus H., Kohane, Isaac S., Gussoni, Emanuela
Publicado 2006

Corrigendum to ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa [Cytotherapy 25 (2023) 782–788/1562]

por Dieter, Kathrin, Niebergall-Roth, Elke, Daniele, Cristina, Fluhr, Silvia, Frank, Natasha Y., Ganss, Christoph, Kiritsi, Dimitra, McGrath, John A., Tolar, Jakub, Frank, Markus H., Kluth, Mark A.
Publicado 2023

ABCB5+ Limbal Epithelial Stem Cells Inhibit Developmental but Promote Inflammatory (Lymph) Angiogenesis While Preventing Corneal Inflammation

por Meshko, Berbang, Volatier, Thomas L. A., Hadrian, Karina, Deng, Shuya, Hou, Yanhong, Kluth, Mark Andreas, Ganss, Christoph, Frank, Markus H., Frank, Natasha Y., Ksander, Bruce, Cursiefen, Claus, Notara, Maria
Publicado 2023

Homozygous TRPV4 mutation causes congenital distal spinal muscular atrophy and arthrogryposis

por Velilla, Jose, Marchetti, Michael Mario, Toth-Petroczy, Agnes, Grosgogeat, Claire, Bennett, Alexis H., Carmichael, Nikkola, Estrella, Elicia, Darras, Basil T., Frank, Natasha Y., Krier, Joel, Gaudet, Rachelle, Gupta, Vandana A.
Publicado 2019

Suppression of Neutrophil-Mediated Tissue Damage—A Novel Skill of Mesenchymal Stem Cells

por Jiang, Dongsheng, Muschhammer, Jana, Qi, Yu, Kügler, Andrea, De Vries, Juliane C., Saffarzadeh, Mona, Sindrilaru, Anca, Beken, Seppe Vander, Wlaschek, Meinhard, Kluth, Mark A., Ganss, Christoph, Frank, Natasha Y., Frank, Markus H., Preissner, Klaus T., Scharffetter-Kochanek, Karin
Publicado 2016

Rapid generation of Col7a1(−/−) mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

por Webber, Beau R., O’Connor, Kyle T., McElmurry, Ron T., Durgin, Elise N., Eide, Cindy, Lees, Christopher J., Riddle, Megan J., Mathews, Wendy, Frank, Natasha Y., Kluth, Mark A., Ganss, Christoph, Moriarity, Branden S., Frank, Markus H., Osborn, Mark J., Tolar, Jakub
Publicado 2017

Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation

por Sasamoto, Yuzuru, Lee, Catherine A.A., Wilson, Brian J., Buerger, Florian, Martin, Gabrielle, Mishra, Ananda, Kiritoshi, Shoko, Tran, Johnathan, Gonzalez, Gabriel, Hildebrandt, Friedhelm, Jo, Vickie Y., Lian, Christine G., Murphy, George F., Ksander, Bruce R., Frank, Markus H., Frank, Natasha Y.
Publicado 2022

In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials

por TAPPENBECK, NILS, SCHRÖDER, HANNES M., NIEBERGALL-ROTH, ELKE, HASSINGER, FATHEMA, DEHIO, ULF, DIETER, KATHRIN, KRAFT, KORINNA, KERSTAN, ANDREAS, ESTERLECHNER, JASMINA, FRANK, NATASHA Y., SCHARFFETTER-KOCHANEK, KARIN, MURPHY, GEORGE F., ORGILL, DENNIS P., BECK, JOACHIM, FRANK, MARKUS H., GANSS, CHRISTOPH, KLUTH, MARK A.
Publicado 2019

Process development and safety evaluation of ABCB5(+) limbal stem cells as advanced-therapy medicinal product to treat limbal stem cell deficiency

por Norrick, Alexandra, Esterlechner, Jasmina, Niebergall-Roth, Elke, Dehio, Ulf, Sadeghi, Samar, Schröder, Hannes M., Ballikaya, Seda, Stemler, Nicole, Ganss, Christoph, Dieter, Kathrin, Dachtler, Ann-Kathrin, Merz, Patrick, Sel, Saadettin, Chodosh, James, Cursiefen, Claus, Frank, Natasha Y., Auffarth, Gerd U., Ksander, Bruce, Frank, Markus H., Kluth, Mark A.
Publicado 2021

Ex vivo-expanded highly pure ABCB5(+) mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process val...

por Kerstan, Andreas, Niebergall-Roth, Elke, Esterlechner, Jasmina, Schröder, Hannes M., Gasser, Martin, Waaga-Gasser, Ana M., Goebeler, Matthias, Rak, Katrin, Schrüfer, Philipp, Endres, Sabrina, Hagenbusch, Petra, Kraft, Korinna, Dieter, Kathrin, Ballikaya, Seda, Stemler, Nicole, Sadeghi, Samar, Tappenbeck, Nils, Murphy, George F., Orgill, Dennis P., Frank, Natasha Y., Ganss, Christoph, Scharffetter-Kochanek, Karin, Frank, Markus H., Kluth, Mark A.
Publicado 2020

Clinical trial of ABCB5(+) mesenchymal stem cells for recessive dystrophic epidermolysis bullosa

por Kiritsi, Dimitra, Dieter, Kathrin, Niebergall-Roth, Elke, Fluhr, Silvia, Daniele, Cristina, Esterlechner, Jasmina, Sadeghi, Samar, Ballikaya, Seda, Erdinger, Leoni, Schauer, Franziska, Gewert, Stella, Laimer, Martin, Bauer, Johann W., Hovnanian, Alain, Zambruno, Giovanna, El Hachem, May, Bourrat, Emmanuelle, Papanikolaou, Maria, Petrof, Gabriela, Kitzmüller, Sophie, Ebens, Christen L., Frank, Markus H., Frank, Natasha Y., Ganss, Christoph, Martinez, Anna E., McGrath, John A., Tolar, Jakub, Kluth, Mark A.
Publicado 2021

Translational development of ABCB5(+) dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

por Kerstan, Andreas, Dieter, Kathrin, Niebergall-Roth, Elke, Klingele, Sabrina, Jünger, Michael, Hasslacher, Christoph, Daeschlein, Georg, Stemler, Lutz, Meyer-Pannwitt, Ulrich, Schubert, Kristin, Klausmann, Gerhard, Raab, Titus, Goebeler, Matthias, Kraft, Korinna, Esterlechner, Jasmina, Schröder, Hannes M., Sadeghi, Samar, Ballikaya, Seda, Gasser, Martin, Waaga-Gasser, Ana M., Murphy, George F., Orgill, Dennis P., Frank, Natasha Y., Ganss, Christoph, Scharffetter-Kochanek, Karin, Frank, Markus H., Kluth, Mark A.
Publicado 2022

Allogeneic ABCB5(+) Mesenchymal Stem Cells for Treatment-Refractory Chronic Venous Ulcers: A Phase I/IIa Clinical Trial

por Kerstan, Andreas, Dieter, Kathrin, Niebergall-Roth, Elke, Dachtler, Ann-Kathrin, Kraft, Korinna, Stücker, Markus, Daeschlein, Georg, Jünger, Michael, Görge, Tobias, Meyer-Pannwitt, Ulrich, Erfurt-Berge, Cornelia, von Engelhardt, Charlotte, Klare, Andreas, Pfeiffer, Christiane, Esterlechner, Jasmina, Schröder, Hannes M., Gasser, Martin, Waaga-Gasser, Ana M., Goebeler, Matthias, Ballikaya, Seda, Sadeghi, Samar, Murphy, George F., Orgill, Dennis P., Frank, Natasha Y., Ganss, Christoph, Scharffetter-Kochanek, Karin, Frank, Markus H., Kluth, Mark A.
Publicado 2021

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery

por Haghighi, Alireza, Krier, Joel B., Toth-Petroczy, Agnes, Cassa, Christopher A., Frank, Natasha Y., Carmichael, Nikkola, Fieg, Elizabeth, Bjonnes, Andrew, Mohanty, Anwoy, Briere, Lauren C., Lincoln, Sharyn, Lucia, Stephanie, Gupta, Vandana A., Söylemez, Onuralp, Sutti, Sheila, Kooshesh, Kameron, Qiu, Haiyan, Fay, Christopher J., Perroni, Victoria, Valerius, Jamie, Hanna, Meredith, Frank, Alexander, Ouahed, Jodie, Snapper, Scott B., Pantazi, Angeliki, Chopra, Sameer S., Leshchiner, Ignaty, Stitziel, Nathan O., Feldweg, Anna, Mannstadt, Michael, Loscalzo, Joseph, Sweetser, David A., Liao, Eric, Stoler, Joan M., Nowak, Catherine B., Sanchez-Lara, Pedro A., Klein, Ophir D., Perry, Hazel, Patsopoulos, Nikolaos A., Raychaudhuri, Soumya, Goessling, Wolfram, Green, Robert C., Seidman, Christine E., MacRae, Calum A., Sunyaev, Shamil R., Maas, Richard L., Vuzman, Dana
Publicado 2018