Enhanced antitumor activity of a novel, oral, helper epitope-containing WT1 protein vaccine in a model of murine leukemia

por Minagawa, Hikaru, Hashii, Yoshiko, Nakajima, Hiroko, Fujiki, Fumihiro, Morimoto, Soyoko, Nakata, Jun, Shirakawa, Toshiro, Katayama, Takane, Tsuboi, Akihiro, Ozono, Keiichi
Publicado 2023

Imaging Assessment of Tumor Response in the Era of Immunotherapy

por Nakata, Jun, Isohashi, Kayako, Oka, Yoshihiro, Nakajima, Hiroko, Morimoto, Soyoko, Fujiki, Fumihiro, Oji, Yusuke, Tsuboi, Akihiro, Kumanogoh, Atsushi, Hashimoto, Naoya, Hatazawa, Jun, Sugiyama, Haruo
Publicado 2021

WT1 Peptide Cancer Vaccine for Patients with Hematopoietic Malignancies and Solid Cancers

por Oka, Yoshihiro, Tsuboi, Akihiro, Elisseeva, Olga A., Nakajima, Hiroko, Fujiki, Fumihiro, Kawakami, Manabu, Shirakata, Toshiaki, Nishida, Sumiyuki, Hosen, Naoki, Oji, Yusuke, Kawase, Ichiro, Sugiyama, Haruo
Publicado 2007

A phase I clinical study of a cocktail vaccine of Wilms’ tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma

por Tsuboi, Akihiro, Hashimoto, Naoya, Fujiki, Fumihiro, Morimoto, Soyoko, Kagawa, Naoki, Nakajima, Hiroko, Hosen, Naoki, Nishida, Sumiyuki, Nakata, Jun, Morita, Satoshi, Sakamoto, Junichi, Oji, Yusuke, Oka, Yoshihiro, Sugiyama, Haruo
Publicado 2018

An oral WT1 protein vaccine composed of WT1-anchored, genetically engineered Bifidobacterium longum allows for intestinal immunity in mice with acute myeloid leukemia

por Nakagawa, Natsuki, Hashii, Yoshiko, Kayama, Hisako, Okumura, Ryu, Nakajima, Hiroko, Minagawa, Hikaru, Morimoto, Soyoko, Fujiki, Fumihiro, Nakata, Jun, Shirakawa, Toshiro, Katayama, Takane, Takeda, Kiyoshi, Tsuboi, Akihiro, Ozono, Keiichi
Publicado 2022

An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells

por Hasegawa, Kana, Tanaka, Satomi, Fujiki, Fumihiro, Morimoto, Soyoko, Nakajima, Hiroko, Tatsumi, Naoya, Nakata, Jun, Takashima, Satoshi, Nishida, Sumiyuki, Tsuboi, Akihiro, Oka, Yoshihiro, Oji, Yusuke, Kumanogoh, Atsushi, Sugiyama, Haruo, Hosen, Naoki
Publicado 2015

Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity

por Morimoto, Soyoko, Fujiki, Fumihiro, Kondo, Kenta, Nakajima, Hiroko, Kobayashi, Yoshiki, Inatome, Miki, Aoyama, Nao, Nishida, Yuya, Tsuboi, Akihiro, Oka, Yoshihiro, Nishida, Sumiyuki, Nakata, Jun, Hosen, Naoki, Oji, Yusuke, Sugiyama, Haruo
Publicado 2018

Extremely strong infiltration of WT1-specific CTLs into mouse tumor by the combination vaccine with WT1-specific CTL and helper peptides

por Nakata, Jun, Nakajima, Hiroko, Hayashibara, Hiromu, Imafuku, Kanako, Morimoto, Soyoko, Fujiki, Fumihiro, Motooka, Daisuke, Okuzaki, Daisuke, Hasegawa, Kana, Hosen, Naoki, Tsuboi, Akihiro, Oka, Yoshihiro, Kumanogoh, Atsushi, Oji, Yusuke, Sugiyama, Haruo
Publicado 2018

Efficient and Non-genotoxic RNA-Based Engineering of Human T Cells Using Tumor-Specific T Cell Receptors With Minimal TCR Mispairing

por Campillo-Davo, Diana, Fujiki, Fumihiro, Van den Bergh, Johan M. J., De Reu, Hans, Smits, Evelien L. J. M., Goossens, Herman, Sugiyama, Haruo, Lion, Eva, Berneman, Zwi N., Van Tendeloo, Viggo
Publicado 2018

Regeneration of Tumor-Antigen-Specific Cytotoxic T Lymphocytes from iPSCs Transduced with Exogenous TCR Genes

por Maeda, Takuya, Nagano, Seiji, Kashima, Soki, Terada, Koji, Agata, Yasutoshi, Ichise, Hiroshi, Ohtaka, Manami, Nakanishi, Mahito, Fujiki, Fumihiro, Sugiyama, Haruo, Kitawaki, Toshio, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi, Masuda, Kyoko, Kawamoto, Hiroshi
Publicado 2020

Establishment of a novel NFAT-GFP reporter platform useful for the functional avidity maturation of HLA class II-restricted TCRs

por Fujiki, Fumihiro, Morimoto, Soyoko, Nishida, Yuya, Tanii, Satoe, Aoyama, Nao, Inatome, Miki, Inoue, Kento, Katsuhara, Akiko, Nakajima, Hiroko, Nakata, Jun, Nishida, Sumiyuki, Tsuboi, Akihiro, Oka, Yoshihiro, Oji, Yusuke, Sogo, Shinji, Sugiyama, Haruo
Publicado 2023

Syndecan-4 as a biomarker to predict clinical outcome for glioblastoma multiforme treated with WT1 peptide vaccine

por Takashima, Satoshi, Oka, Yoshihiro, Fujiki, Fumihiro, Morimoto, Soyoko, Nakajima, Hiroko, Nakae, Yoshiki, Nakata, Jun, Nishida, Sumiyuki, Hosen, Naoki, Tatsumi, Naoya, Mizuguchi, Kenji, Hashimoto, Naoya, Oji, Yusuke, Tsuboi, Akihiro, Kumanogoh, Atsushi, Sugiyama, Haruo
Publicado 2016

Immune adjuvant therapy using Bacillus Calmette–Guérin cell wall skeleton (BCG-CWS) in advanced malignancies: A phase 1 study of safety and immunogenicity assessments

por Nishida, Sumiyuki, Tsuboi, Akihiro, Tanemura, Atsushi, Ito, Toshinori, Nakajima, Hiroko, Shirakata, Toshiaki, Morimoto, Soyoko, Fujiki, Fumihiro, Hosen, Naoki, Oji, Yusuke, Kumanogoh, Atsushi, Kawase, Ichiro, Oka, Yoshihiro, Azuma, Ichiro, Morita, Satoshi, Sugiyama, Haruo
Publicado 2019

Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4(+) T Cell Epitopes of Tumor-Associated Antigens

por Yatsuda, Junji, Irie, Atsushi, Harada, Kumiko, Michibata, Yayoi, Tsukamoto, Hirotake, Senju, Satoru, Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Abu Sayem, Mohammad, Takeda, Naoki, Shibuya, Isao, Sogo, Shinji, Fujiki, Fumihiro, Sugiyama, Haruo, Eto, Masatoshi, Nishimura, Yasuharu
Publicado 2013

T Cell-Intrinsic Vitamin A Metabolism and Its Signaling Are Targets for Memory T Cell-Based Cancer Immunotherapy

por Fujiki, Fumihiro, Morimoto, Soyoko, Katsuhara, Akiko, Okuda, Akane, Ogawa, Saeka, Ueda, Eriko, Miyazaki, Maki, Isotani, Ayako, Ikawa, Masahito, Nishida, Sumiyuki, Nakajima, Hiroko, Tsuboi, Akihiro, Oka, Yoshihiro, Nakata, Jun, Hosen, Naoki, Kumanogoh, Atsushi, Oji, Yusuke, Sugiyama, Haruo
Publicado 2022

A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches

por Versteven, Maarten, Van den Bergh, Johan M.J., Broos, Katrijn, Fujiki, Fumihiro, Campillo-Davo, Diana, De Reu, Hans, Morimoto, Soyoko, Lecocq, Quentin, Keyaerts, Marleen, Berneman, Zwi, Sugiyama, Haruo, Van Tendeloo, Viggo F.I., Breckpot, Karine, Lion, Eva
Publicado 2018

Identification of a Novel C-Terminal Truncated WT1 Isoform with Antagonistic Effects against Major WT1 Isoforms

por Tatsumi, Naoya, Hojo, Nozomi, Sakamoto, Hiroyuki, Inaba, Rena, Moriguchi, Nahoko, Matsuno, Keiko, Fukuda, Mari, Matsumura, Akihide, Hayashi, Seiji, Morimoto, Soyoko, Nakata, Jun, Fujiki, Fumihiro, Nishida, Sumiyuki, Nakajima, Hiroko, Tsuboi, Akihiro, Oka, Yoshihiro, Hosen, Naoki, Sugiyama, Haruo, Oji, Yusuke
Publicado 2015

WT1 epitope-specific IgG and IgM antibodies for immune-monitoring in patients with advanced sarcoma treated with a WT1 peptide cancer vaccine

por Alzaaqi, Shouq, Naka, Norifumi, Hamada, Kenichiro, Hosen, Naoki, Kanegae, Mizuki, Outani, Hidetatsu, Adachi, Mayuko, Imanishi, Rin, Morii, Eiichi, Iwai, Miki, Nakata, Jun, Fujiki, Fumihiro, Morimoto, Soyoko, Nakajima, Hiroko, Nishida, Sumiyuki, Tsuboi, Akihiro, Oka, Yoshihiro, Sugiyama, Haruo, Oji, Yusuke
Publicado 2022

Enhanced immune reaction resulting from co-vaccination of WT1 helper peptide assessed on PET-CT

por Nakata, Jun, Isohashi, Kayako, Morimoto, Soyoko, Itou, Ryota, Kamiya, Takashi, Matsuura, Ai, Nakajima, Hiroko, Fujiki, Fumihiro, Nishida, Sumiyuki, Hasii, Yoshiko, Hasegawa, Kana, Nakatsuka, Shinichi, Hosen, Naoki, Tsuboi, Akihiro, Oka, Yoshihiro, Kumanogoh, Atsushi, Shibano, Masaru, Munakata, Satoru, Oji, Yusuke, Hatazawa, Jun, Sugiyama, Haruo
Publicado 2020

Cellular and Humoral Immune Responses Induced by an HLA Class I–restricted Peptide Cancer Vaccine Targeting WT1 Are Associated With Favorable Clinical Outcomes in Advanced Ovarian...

por Nishida, Sumiyuki, Morimoto, Soyoko, Oji, Yusuke, Morita, Satoshi, Shirakata, Toshiaki, Enomoto, Takayuki, Tsuboi, Akihiro, Ueda, Yutaka, Yoshino, Kiyoshi, Shouq, Alzaaqi, Kanegae, Mizuki, Ohno, Satoshi, Fujiki, Fumihiro, Nakajima, Hiroko, Nakae, Yoshiki, Nakata, Jun, Hosen, Naoki, Kumanogoh, Atsushi, Oka, Yoshihiro, Kimura, Tadashi, Sugiyama, Haruo
Publicado 2022