Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp

por Fujisawa, Ryo, Ohashi, Eiji, Hirota, Kouji, Tsurimoto, Toshiki
Publicado 2017

Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase

por Fujisawa, Ryo, Polo Rivera, Cristian, Labib, Karim PM
Publicado 2022

Brainstem Venous Congestion Due to Transverse-sigmoid Sinus Dural Arteriovenous Fistula: Case Report and Literature Review

por TSUJI, Keiichi, TSUJI, Atsushi, YOSHIMURA, Yayoi, KAWANO, Hiroto, FUJISAWA, Ryo, NOZAKI, Kazuhiko
Publicado 2021

DONSON is required for CMG helicase assembly in the mammalian cell cycle

por Evrin, Cecile, Alvarez, Vanesa, Ainsworth, Johanna, Fujisawa, Ryo, Alabert, Constance, Labib, Karim PM
Publicado 2023

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

por Deegan, Tom D, Mukherjee, Progya P, Fujisawa, Ryo, Polo Rivera, Cristian, Labib, Karim
Publicado 2020

TIMELESS‐TIPIN and UBXN‐3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans

por Xia, Yisui, Fujisawa, Ryo, Deegan, Tom D, Sonneville, Remi, Labib, Karim P M
Publicado 2021

Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex

por Kowalska, Ewa, Bartnicki, Filip, Fujisawa, Ryo, Bonarek, Piotr, Hermanowicz, Paweł, Tsurimoto, Toshiki, Muszyńska, Klaudia, Strzalka, Wojciech
Publicado 2018

CUL2(LRR1), TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle

por Villa, Fabrizio, Fujisawa, Ryo, Ainsworth, Johanna, Nishimura, Kohei, Lie‐A‐Ling, Michael, Lacaud, Georges, Labib, Karim PM
Publicado 2021

Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells

por Yang, Chi-Chun, Suzuki, Masahiro, Yamakawa, Shiori, Uno, Syuzi, Ishii, Ai, Yamazaki, Satoshi, Fukatsu, Rino, Fujisawa, Ryo, Sakimura, Kenji, Tsurimoto, Toshiki, Masai, Hisao
Publicado 2016

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease

por Canal, Berta, Fujisawa, Ryo, McClure, Allison W., Deegan, Tom D., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S., Bertolin, Agustina P., Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F.X.
Publicado 2021

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C)

por Tsuda, Masataka, Terada, Kazuhiro, Ooka, Masato, Kobayashi, Koji, Sasanuma, Hiroyuki, Fujisawa, Ryo, Tsurimoto, Toshiki, Yamamoto, Junpei, Iwai, Shigenori, Kadoda, Kei, Akagawa, Remi, Huang, Shar-Yin Naomi, Pommier, Yves, Sale, Julian E., Takeda, Shunichi, Hirota, Kouji
Publicado 2017

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

por Canal, Berta, McClure, Allison W., Curran, Joseph F., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P., Milligan, Jennifer C., Basu, Souradeep, Drury, Lucy S., Deegan, Tom D., Fujisawa, Ryo, Roberts, Emma L., Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

por Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F., Drury, Lucy S., McClure, Allison W., Roberts, Emma L., Weissmann, Florian, Zeisner, Theresa U., Beale, Rupert, Cowling, Victoria H., Howell, Michael, Labib, Karim, Diffley, John F.X.
Publicado 2021

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease

por Milligan, Jennifer C., Zeisner, Theresa U., Papageorgiou, George, Joshi, Dhira, Soudy, Christelle, Ulferts, Rachel, Wu, Mary, Lim, Chew Theng, Tan, Kang Wei, Weissmann, Florian, Canal, Berta, Fujisawa, Ryo, Deegan, Tom, Nagaraj, Hema, Bineva-Todd, Ganka, Basier, Clovis, Curran, Joseph F., Howell, Michael, Beale, Rupert, Labib, Karim, O'Reilly, Nicola, Diffley, John F.X.
Publicado 2021