Simple and Rapid Enzymatic Method for the Synthesis of Single-Strand Oligonucleotides Containing Trifluorothymidine

por Suzuki, Norihiko, Fukushima, Masakazu
Publicado 2010

Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis

por SHIMAMOTO, YUJI, NUKATSUKA, MAMORU, TAKECHI, TEIJI, FUKUSHIMA, MASAKAZU
Publicado 2016

Pharmacokinetic Modulation of Plasma 5‐Fluorouracil Concentrations to Potentiate the Antitumor Activity of Continuous Venous Infusion of 5‐Fluorouracil

por Fujii, Setsuro, Fukushima, Masakazu, Shimamoto, Yuji, Shirasaka, Tetsuhiko
Publicado 1989

Screening of Differentially Expressed Genes in 5‐Fluorouracil‐resistant Human Gastrointestinal Tumor Cells

por Takechi, Teiji, Koizumi, Katsuhisa, Tsujimoto, Hiroaki, Fukushima, Masakazu
Publicado 2001

Relationship between Protein Levels and Gene Expression of Dihydropyrimidine Dehydrogenase in Human Tumor Cells during Growth in Culture and in Nude Mice

por Takechi, Teiji, Okabe, Hiroyuki, Fujioka, Akio, Murakami, Yuko, Fukushima, Masakazu
Publicado 1998

Development of new promising antimetabolite, DFP-11207 with self-controlled toxicity in rodents

por Fukushima, Masakazu, Iizuka, Kenzo, Jin, Cheng, Zhang, Chun, Hong, Mei, Eshima, Kiyoshi
Publicado 2017

Antitumor Activity of BOF‐A2, a New 5‐Fluorouracil Derivative

por Fujii, Setsuro, Fukushima, Masakazu, Shimamoto, Yuji, Ohshimo, Hideyuki, Imaoka, Takeshi, Shirasaka, Tetsuhiko
Publicado 1989

Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian ca...

por Iizuka, Kenzo, Jin, Cheng, Eshima, Kokoro, Hong, Mei Hua, Eshima, Kiyoshi, Fukushima, Masakazu
Publicado 2018

Effects of the Plasma Concentration of 5‐Fluorouracil and the Duration of Continuous Venous Infusion of 5‐Fluorouracil with an Inhibitor of 5‐Fluorouracil Degradation on Yoshida Sa...

por Fujii, Setsuro, Shimamoto, Yuji, Ohshimo, Hideyuki, Imaoka, Takeshi, Motoyama, Masaaki, Fukushima, Masakazu, Shirasaka, Tetsuhiko
Publicado 1989

Expression of Thymidylate Synthase in Human Non‐small Cell Lung Cancer

por Otake, Yosuke, Tanaka, Fumihiro, Yanagihara, Kazuhiro, Hitomi, Shigeki, Okabe, Hiroyuki, Fukushima, Masakazu, Wada, Hiromi
Publicado 1999

Cellular and Biochemical Mechanisms of the Resistance of Human Cancer Cells to a New Anticancer Ribo‐nucleoside, TAS‐106

por Shimamoto, Yuji, Kazuno, Hiromi, Murakami, Yuko, Azuma, Atsushi, Koizumi, Katsuhisa, Matsuda, Akira, Sasaki, Takuma, Fukushima, Masakazu
Publicado 2002

A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression

por Meike, Shunsuke, Yamamori, Tohru, Yasui, Hironobu, Eitaki, Masato, Matsuda, Akira, Morimatsu, Masami, Fukushima, Masakazu, Yamasaki, Yasundo, Inanami, Osamu
Publicado 2011

Reduced Activity of Anabolizing Enzymes in 5‐Fluorouracil‐resistant Human Stomach Cancer Cells

por Inaba, Makoto, Mitsuhashi, Junko, Sawada, Hiroko, Miike, Naoko, Naoe, Yoshinori, Daimon, Aiko, Koizumi, Kazuhisa, Tsujimoto, Hiroaki, Fukushima, Masakazu
Publicado 1996

Antitumor Activity and Pharmacokinetics of TAS‐106, l‐(3‐C‐Ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosine

por Shimamoto, Yuji, Fujioka, Akio, Kazuno, Hiromi, Murakami, Yuko, Ohshimo, Hideyuki, Kato, Toshiyuki, Matsuda, Akira, Sasaki, Takuma, Fukushima, Masakazu
Publicado 2001

Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2

por Shimamoto, Yuji, Koizumi, Katsuhisa, Okabe, Hiroyuki, Kazuno, Hiromi, Murakami, Yuko, Nakagawa, Fumio, Matsuda, Akira, Sasaki, Takuma, Fukushima, Masakazu
Publicado 2002

A novel intraperitoneal therapy for gastric cancer with DFP‐10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model

por Ando, Hidenori, Fukushima, Masakazu, Eshima, Kiyoshi, Hasui, Taichi, Shimizu, Taro, Ishima, Yu, Huang, Cheng‐Long, Wada, Hiromi, Ishida, Tatsuhiro
Publicado 2019

Dynamic Modulation of Thymidylate Synthase Gene Expression and Fluorouracil Sensitivity in Human Colorectal Cancer Cells

por Wakasa, Kentaro, Kawabata, Rumi, Nakao, Seiki, Hattori, Hiroyoshi, Taguchi, Kenichi, Uchida, Junji, Yamanaka, Takeharu, Maehara, Yoshihiko, Fukushima, Masakazu, Oda, Shinya
Publicado 2015

Dihydropyrimidine Dehydrogenase and Messenger RNA Levels in Gastric Cancer: Possible Predictor for Sensitivity to 5‐Fluorouracil

por Ishikawa, Yoichiro, Kubota, Tetsuro, Otani, Yoshihide, Watanabe, Masahiko, Teramoto, Tatsuo, Kumai, Koichiro, Takechi, Teiji, Okabe, Hiroyuki, Fukushima, Masakazu, Kitajima, Masaki
Publicado 2000

Quantitative Measurement of Thymidylate Synthase and Dihydropyrimidine Dehydrogenase mRNA Level in Gastric Cancer by Real‐time RT‐PCR

por Fujiwara, Hisataka, Terashima, Masanori, Irinoda, Takashi, Takagane, Akinori, Abe, Kaoru, Kashiwaba, Masahiro, Oyama, Kennichi, Takahashi, Masanori, Maesawa, Chihaya, Saito, Kazuyoshi, Takechi, Teiji, Fukushima, Masakazu
Publicado 2002