PI3K/mTOR Pathway Inhibition: Opportunities in Oncology and Rare Genetic Diseases

por Hillmann, Petra, Fabbro, Doriano
Publicado 2019

Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis

por Kotelevets, Nataliya, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe
Publicado 2012

Correction: Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis

por Kotelevets, Nataliya, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe
Publicado 2013

Lipids as Targets for Renal Cell Carcinoma Therapy

por Stepanovska Tanturovska, Bisera, Manaila, Roxana, Fabbro, Doriano, Huwiler, Andrea
Publicado 2023

Phosphorylation, Signaling, and Cancer: Targets and Targeting

por Marmiroli, Sandra, Fabbro, Doriano, Miyata, Yoshihiko, Pierobon, Mariaelena, Ruzzene, Maria
Publicado 2015

Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia

por Cowan-Jacob, Sandra W., Fendrich, Gabriele, Floersheimer, Andreas, Furet, Pascal, Liebetanz, Janis, Rummel, Gabriele, Rheinberger, Paul, Centeleghe, Mario, Fabbro, Doriano, Manley, Paul W.
Publicado 2006

7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes†

por Huber, Kilian, Brault, Laurent, Fedorov, Oleg, Gasser, Christelle, Filippakopoulos, Panagis, Bullock, Alex N., Fabbro, Doriano, Trappe, Jörg, Schwaller, Jürg, Knapp, Stefan, Bracher, Franz
Publicado 2011

Preclinical Development of PQR514, a Highly Potent PI3K Inhibitor Bearing a Difluoromethyl–Pyrimidine Moiety

por Borsari, Chiara, Rageot, Denise, Beaufils, Florent, Bohnacker, Thomas, Keles, Erhan, Buslov, Ivan, Melone, Anna, Sele, Alexander M., Hebeisen, Paul, Fabbro, Doriano, Hillmann, Petra, Wymann, Matthias P.
Publicado 2019

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

por Fedorov, Oleg, Huber, Kilian, Eisenreich, Andreas, Filippakopoulos, Panagis, King, Oliver, Bullock, Alex N., Szklarczyk, Damian, Jensen, Lars J., Fabbro, Doriano, Trappe, Jörg, Rauch, Ursula, Bracher, Franz, Knapp, Stefan
Publicado 2011

The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors

por Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A
Publicado 2015

The Concise Guide to PHARMACOLOGY 2015/16: Enzymes

por Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A
Publicado 2015

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors

por Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A
Publicado 2017

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

por Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A
Publicado 2017

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology

por Harding, Simon D., Faccenda, Elena, Southan, Christopher, Pawson, Adam J., Maffia, Pasquale, Alexander, Stephen P. H., Davenport, Anthony P., Fabbro, Doriano, Levi‐Schaffer, Francesca, Spedding, Michael, Davies, Jamie A.
Publicado 2020

The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax

por Tarantelli, Chiara, Gaudio, Eugenio, Hillmann, Petra, Spriano, Filippo, Sartori, Giulio, Aresu, Luca, Cascione, Luciano, Rageot, Denise, Kwee, Ivo, Beaufils, Florent, Zucca, Emanuele, Stathis, Anastasios, Wymann, Matthias P., Cmiljanovic, Vladimir, Fabbro, Doriano, Bertoni, Francesco
Publicado 2019

Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

por Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi
Publicado 2018

Author Correction: Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

por Kreamer, Naomi N. K., Chopra, Rajiv, Caughlan, Ruth E., Fabbro, Doriano, Fang, Eric, Gee, Patricia, Hunt, Ian, Li, Min, Leon, Barbara C., Muller, Lionel, Vash, Brian, Woods, Angela L., Stams, Travis, Dean, Charles R., Uehara, Tsuyoshi
Publicado 2018

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

por Southan, Christopher, Sharman, Joanna L., Benson, Helen E., Faccenda, Elena, Pawson, Adam J., Alexander, Stephen P. H., Buneman, O. Peter, Davenport, Anthony P., McGrath, John C., Peters, John A., Spedding, Michael, Catterall, William A., Fabbro, Doriano, Davies, Jamie A.
Publicado 2016

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

por Harding, Simon D, Sharman, Joanna L, Faccenda, Elena, Southan, Chris, Pawson, Adam J, Ireland, Sam, Gray, Alasdair J G, Bruce, Liam, Alexander, Stephen P H, Anderton, Stephen, Bryant, Clare, Davenport, Anthony P, Doerig, Christian, Fabbro, Doriano, Levi-Schaffer, Francesca, Spedding, Michael, Davies, Jamie A
Publicado 2018

Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

por Bohnacker, Thomas, Prota, Andrea E., Beaufils, Florent, Burke, John E., Melone, Anna, Inglis, Alison J., Rageot, Denise, Sele, Alexander M., Cmiljanovic, Vladimir, Cmiljanovic, Natasa, Bargsten, Katja, Aher, Amol, Akhmanova, Anna, Díaz, J. Fernando, Fabbro, Doriano, Zvelebil, Marketa, Williams, Roger L., Steinmetz, Michel O., Wymann, Matthias P.
Publicado 2017