The EDC4‐XRN1 interaction controls P‐body dynamics to link mRNA decapping with decay

por Brothers, William R, Ali, Farah, Kajjo, Sam, Fabian, Marc R
Publicado 2023

P-bodies directly regulate MARF1-mediated mRNA decay in human cells

por Brothers, William R, Fakim, Hana, Kajjo, Sam, Fabian, Marc R
Publicado 2022

A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay

por Brothers, William R, Hebert, Steven, Kleinman, Claudia L, Fabian, Marc R
Publicado 2020

HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA

por Kundu, Pradipta, Fabian, Marc R., Sonenberg, Nahum, Bhattacharyya, Suvendra N., Filipowicz, Witold
Publicado 2012

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation

por Jinek, Martin, Fabian, Marc R., Coyle, Scott M., Sonenberg, Nahum, Doudna, Jennifer A.
Publicado 2010

Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1

por Rouya, Christopher, Siddiqui, Nadeem, Morita, Masahiro, Duchaine, Thomas F., Fabian, Marc R., Sonenberg, Nahum
Publicado 2014

Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry

por Cieplak-Rotowska, Maja K., Tarnowski, Krzysztof, Rubin, Marcin, Fabian, Marc R., Sonenberg, Nahum, Dadlez, Michal, Niedzwiecka, Anna
Publicado 2017

Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs

por Nishimura, Tamiko, Fakim, Hana, Brandmann, Tobias, Youn, Ji-Young, Gingras, Anne-Claude, Jinek, Martin, Fabian, Marc R
Publicado 2018

DICER1 platform domain missense variants inhibit miRNA biogenesis and lead to tumor susceptibility

por Pelletier, Dylan, Chong, Anne-Laure, Wu, Mona, Witkowski, Leora, Albert, Sophie, Sabbaghian, Nelly, Fabian, Marc R, Foulkes, William D
Publicado 2023

Control of Translation and miRNA-Dependent Repression by a Novel Poly(A) Binding Protein, hnRNP-Q

por Svitkin, Yuri V., Yanagiya, Akiko, Karetnikov, Alexey E., Alain, Tommy, Fabian, Marc R., Khoutorsky, Arkady, Perreault, Sandra, Topisirovic, Ivan, Sonenberg, Nahum
Publicado 2013

An oxygen-regulated switch in the protein synthesis machinery

por Uniacke, James, Holterman, Chet E., Lachance, Gabriel, Franovic, Aleksandra, Jacob, Mathieu D., Fabian, Marc R., Payette, Josianne, Holcik, Martin, Pause, Arnim, Lee, Stephen
Publicado 2012

Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200

por Choquet, Karine, Forget, Diane, Meloche, Elisabeth, Dicaire, Marie-Josée, Bernard, Geneviève, Vanderver, Adeline, Schiffmann, Raphael, Fabian, Marc R., Teichmann, Martin, Coulombe, Benoit, Brais, Bernard, Kleinman, Claudia L.
Publicado 2019

CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair

por Hilmi, Khalid, Jangal, Maïka, Marques, Maud, Zhao, Tiejun, Saad, Amine, Zhang, Chenxi, Luo, Vincent M., Syme, Alasdair, Rejon, Carlis, Yu, Zhenbao, Krum, Asiev, Fabian, Marc R., Richard, Stéphane, Alaoui-Jamali, Moulay, Orthwein, Alexander, McCaffrey, Luke, Witcher, Michael
Publicado 2017