Structure-Guided Computational Methods Predict Multiple Distinct Binding Modes for Pyrazoloquinolinones in GABA(A) Receptors

por Fabjan, Jure, Koniuszewski, Filip, Schaar, Benjamin, Ernst, Margot
Publicado 2021

Two Distinct Populations of α1α6-Containing GABAA-Receptors in Rat Cerebellum

por Scholze, Petra, Pökl, Michael, Längle, Severin, Steudle, Friederike, Fabjan, Jure, Ernst, Margot
Publicado 2020

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels

por Koniuszewski, Filip, Vogel, Florian D., Bampali, Konstantina, Fabjan, Jure, Seidel, Thomas, Scholze, Petra, Schmiedhofer, Philip B., Langer, Thierry, Ernst, Margot
Publicado 2022

Towards functional selectivity for α6β3γ2 GABA(A) receptors: a series of novel pyrazoloquinolinones

por Treven, Marco, Siebert, David C B, Holzinger, Raphael, Bampali, Konstantina, Fabjan, Jure, Varagic, Zdravko, Wimmer, Laurin, Steudle, Friederike, Scholze, Petra, Schnürch, Michael, Mihovilovic, Marko D, Ernst, Margot
Publicado 2017

Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness

por Zierfuss, Bettina, Buda, Agnieszka, Villoria-González, Andrea, Logist, Maxime, Fabjan, Jure, Parzer, Patricia, Battin, Claire, Vandersteene, Streggi, Dijkstra, Inge M. E., Waidhofer-Söllner, Petra, Grabmeier-Pfistershammer, Katharina, Steinberger, Peter, Kemp, Stephan, Forss-Petter, Sonja, Berger, Johannes, Weinhofer, Isabelle
Publicado 2022

GABA(A) receptor-mediated seizure liabilities: a mixed-methods screening approach

por Bampali, Konstantina, Koniuszewski, Filip, Vogel, Florian D., Fabjan, Jure, Andronis, Christos, Lekka, Eftychia, Virvillis, Vassilis, Seidel, Thomas, Delaunois, Annie, Royer, Leandro, Rolf, Michael G., Giuliano, Chiara, Traebert, Martin, Roussignol, Gautier, Fric-Bordat, Magali, Mazelin-Winum, Ludmilla, Bryant, Sharon D., Langer, Thierry, Ernst, Margot
Publicado 2023