Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages

por Palmer, Charys, Facchini, Fabio A, Jones, Richard PO, Neumann, Frank, Peri, Francesco, Pirianov, Grisha
Publicado 2021

Co‐administration of Antimicrobial Peptides Enhances Toll‐like Receptor 4 Antagonist Activity of a Synthetic Glycolipid

por Facchini, Fabio A., Coelho, Helena, Sestito, Stefania E., Delgado, Sandra, Minotti, Alberto, Andreu, David, Jiménez‐Barbero, Jesús, Peri, Francesco
Publicado 2018

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation

por Grasselli, Chiara, Ferrari, Daniela, Zalfa, Cristina, Soncini, Matias, Mazzoccoli, Gianluigi, Facchini, Fabio A., Marongiu, Laura, Granucci, Francesca, Copetti, Massimiliano, Vescovi, Angelo Luigi, Peri, Francesco, De Filippis, Lidia
Publicado 2018

Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties

por Cochet, Florent, Facchini, Fabio A., Zaffaroni, Lenny, Billod, Jean-Marc, Coelho, Helena, Holgado, Aurora, Braun, Harald, Beyaert, Rudi, Jerala, Roman, Jimenez-Barbero, Jesus, Martin-Santamaria, Sonsoles, Peri, Francesco
Publicado 2019

Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity

por Facchini, Fabio A., Minotti, Alberto, Luraghi, Andrea, Romerio, Alessio, Gotri, Nicole, Matamoros-Recio, Alejandra, Iannucci, Andrea, Palmer, Charys, Wang, Guanbo, Ingram, Rebecca, Martin-Santamaria, Sonsoles, Pirianov, Grisha, De Andrea, Marco, Valvano, Miguel A., Peri, Francesco
Publicado 2021

Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.

por Sposito, Benedetta, Broggi, Achille, Pandolfi, Laura, Crotta, Stefania, Ferrarese, Roberto, Sisti, Sofia, Clementi, Nicola, Ambrosi, Alessandro, Liu, Enju, Frangipane, Vanessa, Saracino, Laura, Marongiu, Laura, Facchini, Fabio A, Bottazzi, Andrea, Fossali, Tommaso, Colombo, Riccardo, Clementi, Massimo, Tagliabue, Elena, Pontiroli, Antonio E, Meloni, Federica, Wack, Andreas, Mancini, Nicasio, Zanoni, Ivan
Publicado 2021

Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing

por Marongiu, Laura, Protti, Giulia, Facchini, Fabio A., Valache, Mihai, Mingozzi, Francesca, Ranzani, Valeria, Putignano, Anna Rita, Salviati, Lorenzo, Bevilacqua, Valeria, Curti, Serena, Crosti, Mariacristina, Sarnicola, Maria Lucia, D'Angiò, Mariella, Bettini, Laura Rachele, Biondi, Andrea, Nespoli, Luca, Tamini, Nicolò, Clementi, Nicola, Mancini, Nicasio, Abrignani, Sergio, Spreafico, Roberto, Granucci, Francesca
Publicado 2021

The interferon landscape along the respiratory tract impacts the severity of COVID-19

por Sposito, Benedetta, Broggi, Achille, Pandolfi, Laura, Crotta, Stefania, Clementi, Nicola, Ferrarese, Roberto, Sisti, Sofia, Criscuolo, Elena, Spreafico, Roberto, Long, Jaclyn M., Ambrosi, Alessandro, Liu, Enju, Frangipane, Vanessa, Saracino, Laura, Bozzini, Sara, Marongiu, Laura, Facchini, Fabio A., Bottazzi, Andrea, Fossali, Tommaso, Colombo, Riccardo, Clementi, Massimo, Tagliabue, Elena, Chou, Janet, Pontiroli, Antonio E., Meloni, Federica, Wack, Andreas, Mancini, Nicasio, Zanoni, Ivan
Publicado 2021