Autosomal Dominant Alzheimer Disease: A Unique Resource to Study CSF Biomarker Changes in Preclinical AD

por Schindler, Suzanne Elizabeth, Fagan, Anne M.
Publicado 2015

Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes

por Yang, Chengran, Fagan, Anne M., Perrin, Richard J., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos
Publicado 2022

Diurnal oscillation of CSF Aβ and other AD biomarkers

por Lucey, Brendan P., Fagan, Anne M., Holtzman, David M., Morris, John C., Bateman, Randall J.
Publicado 2017

GPS driving: a digital biomarker for preclinical Alzheimer disease

por Bayat, Sayeh, Babulal, Ganesh M., Schindler, Suzanne E., Fagan, Anne M., Morris, John C., Mihailidis, Alex, Roe, Catherine M.
Publicado 2021

Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer’s disease

por Sutphen, Courtney L., McCue, Lena, Herries, Elizabeth M., Xiong, Chengjie, Ladenson, Jack H., Holtzman, David M., Fagan, Anne M.
Publicado 2018

Cerebrospinal Fluid Aβ(42/40) Corresponds Better than Aβ(42) to Amyloid PET in Alzheimer’s Disease

por Lewczuk, Piotr, Matzen, Anja, Blennow, Kaj, Parnetti, Lucilla, Molinuevo, Jose Luis, Eusebi, Paolo, Kornhuber, Johannes, Morris, John C., Fagan, Anne M.
Publicado 2016

Comparing Tau PET Visual Interpretation with Tau PET Quantification, Cerebrospinal Fluid Biomarkers, and Longitudinal Clinical Assessment

por Chen, Charles D., Ponisio, Maria Rosana, Lang, Jordan A., Flores, Shaney, Schindler, Suzanne E., Fagan, Anne M., Morris, John C., Benzinger, Tammie L.S.
Publicado 2023

Plasma Neurofilament Light Chain Levels Are Elevated in Children and Young Adults With Wolfram Syndrome

por Eisenstein, Sarah A., Boodram, Raveena S., Sutphen, Courtney L., Lugar, Heather M., Gordon, Brian A., Marshall, Bess A., Urano, Fumihiko, Fagan, Anne M., Hershey, Tamara
Publicado 2022

Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage

por Meeker, Karin L., Butt, Omar H., Gordon, Brian A., Fagan, Anne M., Schindler, Suzanne E., Morris, John C., Benzinger, Tammie L.S., Ances, Beau M.
Publicado 2022

Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease

por Fagan, Anne M, Mintun, Mark A, Shah, Aarti R, Aldea, Patricia, Roe, Catherine M, Mach, Robert H, Marcus, Daniel, Morris, John C, Holtzman, David M
Publicado 2009

Quantitative Label-Free Proteomics for Discovery of Biomarkers in Cerebrospinal Fluid: Assessment of Technical and Inter-Individual Variation

por Perrin, Richard J., Payton, Jacqueline E., Malone, James P., Gilmore, Petra, Davis, Alan E., Xiong, Chengjie, Fagan, Anne M., Townsend, R. Reid, Holtzman, David M.
Publicado 2013

Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects

por Hata, Saori, Taniguchi, Miyako, Piao, Yi, Ikeuchi, Takeshi, Fagan, Anne M, Holtzman, David M, Bateman, Randall, Sohrabi, Hamid R, Martins, Ralph N, Gandy, Sam, Urakami, Katsuya, Suzuki, Toshiharu
Publicado 2012

Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis

por Craig-Schapiro, Rebecca, Kuhn, Max, Xiong, Chengjie, Pickering, Eve H., Liu, Jingxia, Misko, Thomas P., Perrin, Richard J., Bales, Kelly R., Soares, Holly, Fagan, Anne M., Holtzman, David M.
Publicado 2011

Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer’s disease

por Muenchhoff, Julia, Poljak, Anne, Thalamuthu, Anbupalam, Gupta, Veer B., Chatterjee, Pratishtha, Raftery, Mark, Masters, Colin L., Morris, John C., Bateman, Randall J., Fagan, Anne M., Martins, Ralph N., Sachdev, Perminder S.
Publicado 2016

Data-driven models of dominantly-inherited Alzheimer’s disease progression

por Oxtoby, Neil P, Young, Alexandra L, Cash, David M, Benzinger, Tammie L S, Fagan, Anne M, Morris, John C, Bateman, Randall J, Fox, Nick C, Schott, Jonathan M, Alexander, Daniel C
Publicado 2018

Using the A/T/N Framework to Examine Driving in Preclinical Alzheimer’s Disease

por Roe, Catherine M., Babulal, Ganesh M., Stout, Sarah H., Carr, David B., Williams, Monique M., Benzinger, Tammie L. S., Fagan, Anne M., Holtzman, David M., Ances, Beau M., Morris, John C.
Publicado 2018

Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease

por Wang, Guoqiao, Xiong, Chengjie, McDade, Eric M., Hassenstab, Jason, Aschenbrenner, Andrew J., Fagan, Anne M., Benzinger, Tammie L.S., Gordon, Brian A., Morris, John C., Li, Yan, Bateman, Randall J.
Publicado 2018

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms

por Wahrle, Suzanne E, Shah, Aarti R, Fagan, Anne M, Smemo, Scott, Kauwe, John SK, Grupe, Andrew, Hinrichs, Anthony, Mayo, Kevin, Jiang, Hong, Thal, Leon J, Goate, Alison M, Holtzman, David M
Publicado 2007

Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

por Kauwe, John S. K., Cruchaga, Carlos, Karch, Celeste M., Sadler, Brooke, Lee, Mo, Mayo, Kevin, Latu, Wayne, Su'a, Manti, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.
Publicado 2011

Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome

por Henson, Rachel L., Doran, Eric, Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Lai, Florence, Lee, Joseph H., Rosas, H. Diana, Schupf, Nicole, Zaman, Shahid H., Lott, Ira T., Fagan, Anne M.
Publicado 2020