Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

by Khan, Sofia, Fagerholm, Rainer, Kadalayil, Latha, Tapper, William, Aittomäki, Kristiina, Liu, Jianjun, Blomqvist, Carl, Eccles, Diana, Nevanlinna, Heli
Published 2017

Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications

by Muranen, Taru A, Greco, Dario, Fagerholm, Rainer, Kilpivaara, Outi, Kämpjärvi, Kati, Aittomäki, Kristiina, Blomqvist, Carl, Heikkilä, Päivi, Borg, Åke, Nevanlinna, Heli
Published 2011

Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families

by Muranen, Taru A., Mavaddat, Nasim, Khan, Sofia, Fagerholm, Rainer, Pelttari, Liisa, Lee, Andrew, Aittomäki, Kristiina, Blomqvist, Carl, Easton, Douglas F., Nevanlinna, Heli
Published 2016

High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcome

by Jamshidi, Maral, Fagerholm, Rainer, Muranen, Taru A., Kaur, Sippy, Potdar, Swapnil, Khan, Sofia, Netti, Eliisa, Mpindi, John-Patrick, Yadav, Bhagwan, Kiiski, Johanna I., Aittomäki, Kristiina, Heikkilä, Päivi, Saarela, Jani, Bützow, Ralf, Blomqvist, Carl, Nevanlinna, Heli
Published 2021

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients

by Schmidt, Marjanka K, Tommiska, Johanna, Broeks, Annegien, van Leeuwen, Flora E, Van't Veer, Laura J, Pharoah, Paul DP, Easton, Douglas F, Shah, Mitul, Humphreys, Manjeet, Dörk, Thilo, Reincke, Scarlett A, Fagerholm, Rainer, Blomqvist, Carl, Nevanlinna, Heli
Published 2009

High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer

by Reynisdottir, Inga, Arason, Adalgeir, Einarsdottir, Berglind O, Gunnarsson, Haukur, Staaf, Johan, Vallon-Christersson, Johan, Jonsson, Goran, Ringnér, Markus, Agnarsson, Bjarni A, Olafsdottir, Kristrun, Fagerholm, Rainer, Einarsdottir, Thorbjorg, Johannesdottir, Gudrun, Johannsson, Oskar Thor, Nevanlinna, Heli, Borg, Ake, Barkardottir, Rosa Bjork
Published 2013

FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome

by Kiiski, Johanna I., Fagerholm, Rainer, Tervasmäki, Anna, Pelttari, Liisa M., Khan, Sofia, Jamshidi, Maral, Mantere, Tuomo, Pylkäs, Katri, Bartek, Jiri, Bartkova, Jirina, Mannermaa, Arto, Tengström, Maria, Kosma, Veli‐Matti, Winqvist, Robert, Kallioniemi, Anne, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli
Published 2016

Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

by Jönsson, Göran, Staaf, Johan, Vallon-Christersson, Johan, Ringnér, Markus, Holm, Karolina, Hegardt, Cecilia, Gunnarsson, Haukur, Fagerholm, Rainer, Strand, Carina, Agnarsson, Bjarni A, Kilpivaara, Outi, Luts, Lena, Heikkilä, Päivi, Aittomäki, Kristiina, Blomqvist, Carl, Loman, Niklas, Malmström, Per, Olsson, Håkan, Th Johannsson, Oskar, Arason, Adalgeir, Nevanlinna, Heli, Barkardottir, Rosa B, Borg, Åke
Published 2010

Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis

by Tommiska, Johanna, Känsäkoski, Johanna, Skibsbye, Lasse, Vaaralahti, Kirsi, Liu, Xiaonan, Lodge, Emily J., Tang, Chuyi, Yuan, Lei, Fagerholm, Rainer, Kanters, Jørgen K., Lahermo, Päivi, Kaunisto, Mari, Keski-Filppula, Riikka, Vuoristo, Sanna, Pulli, Kristiina, Ebeling, Tapani, Valanne, Leena, Sankila, Eeva-Marja, Kivirikko, Sirpa, Lääperi, Mitja, Casoni, Filippo, Giacobini, Paolo, Phan-Hug, Franziska, Buki, Tal, Tena-Sempere, Manuel, Pitteloud, Nelly, Veijola, Riitta, Lipsanen-Nyman, Marita, Kaunisto, Kari, Mollard, Patrice, Andoniadou, Cynthia L., Hirsch, Joel A., Varjosalo, Markku, Jespersen, Thomas, Raivio, Taneli
Published 2017

Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers

by Sung, Hyuna, Garcia-Closas, Montserrat, Chang-Claude, Jenny, Blows, Fiona M, Ali, H Raza, Figueroa, Jonine, Nevanlinna, Heli, Fagerholm, Rainer, Heikkilä, Päivi, Blomqvist, Carl, Giles, Graham G, Milne, Roger L, Southey, Melissa C, McLean, Catriona, Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Sironen, Reijo, Couch, Fergus J, Olson, Janet E, Hallberg, Emily, Olswold, Curtis, Cox, Angela, Cross, Simon S, Kraft, Peter, Tamimi, Rulla M, Eliassen, A Heather, Schmidt, Marjanka K, Bolla, Manjeet K, Wang, Qin, Easton, Douglas, Howat, William J, Coulson, Penny, Pharoah, Paul DP, Sherman, Mark E, Yang, Xiaohong R
Published 2016

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

by Muranen, Taru A., Khan, Sofia, Fagerholm, Rainer, Aittomäki, Kristiina, Cunningham, Julie M., Dennis, Joe, Leslie, Goska, McGuffog, Lesley, Parsons, Michael T., Simard, Jacques, Slager, Susan, Soucy, Penny, Easton, Douglas F., Tischkowitz, Marc, Spurdle, Amanda B., Schmutzler, Rita K., Wappenschmidt, Barbara, Hahnen, Eric, Hooning, Maartje J., Singer, Christian F., Wagner, Gabriel, Thomassen, Mads, Pedersen, Inge Sokilde, Domchek, Susan M., Nathanson, Katherine L., Lazaro, Conxi, Rossing, Caroline Maria, Andrulis, Irene L., Teixeira, Manuel R., James, Paul, Garber, Judy, Weitzel, Jeffrey N., Jakubowska, Anna, Yannoukakos, Drakoulis, John, Esther M., Southey, Melissa C., Schmidt, Marjanka K., Antoniou, Antonis C., Chenevix-Trench, Georgia, Blomqvist, Carl, Nevanlinna, Heli
Published 2020

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

by Seibold, Petra, Schmezer, Peter, Behrens, Sabine, Michailidou, Kyriaki, Bolla, Manjeet K., Wang, Qin, Flesch-Janys, Dieter, Nevanlinna, Heli, Fagerholm, Rainer, Aittomäki, Kristiina, Blomqvist, Carl, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Lambrechts, Diether, Wildiers, Hans, Kristensen, Vessela, Alnæs, Grethe Grenaker, Nord, Silje, Borresen-Dale, Anne-Lise, Hooning, Maartje J., Hollestelle, Antoinette, Jager, Agnes, Seynaeve, Caroline, Li, Jingmei, Liu, Jianjun, Humphreys, Keith, Dunning, Alison M., Rhenius, Valerie, Shah, Mitul, Kabisch, Maria, Torres, Diana, Ulmer, Hans-Ulrich, Hamann, Ute, Schildkraut, Joellen M., Purrington, Kristen S., Couch, Fergus J., Hall, Per, Pharoah, Paul, Easton, Doug F., Schmidt, Marjanka K., Chang-Claude, Jenny, Popanda, Odilia
Published 2015

Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium

by Muranen, Taru A., Blomqvist, Carl, Dörk, Thilo, Jakubowska, Anna, Heikkilä, Päivi, Fagerholm, Rainer, Greco, Dario, Aittomäki, Kristiina, Bojesen, Stig E., Shah, Mitul, Dunning, Alison M., Rhenius, Valerie, Hall, Per, Czene, Kamila, Brand, Judith S., Darabi, Hatef, Chang-Claude, Jenny, Rudolph, Anja, Nordestgaard, Børge G., Couch, Fergus J., Hart, Steven N., Figueroa, Jonine, García-Closas, Montserrat, Fasching, Peter A., Beckmann, Matthias W., Li, Jingmei, Liu, Jianjun, Andrulis, Irene L., Winqvist, Robert, Pylkäs, Katri, Mannermaa, Arto, Kataja, Vesa, Lindblom, Annika, Margolin, Sara, Lubinski, Jan, Dubrowinskaja, Natalia, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Easton, Douglas F., Pharoah, Paul D. P., Schmidt, Marjanka K., Nevanlinna, Heli
Published 2016

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

by Fagerholm, Rainer, Schmidt, Marjanka K., Khan, Sofia, Rafiq, Sajjad, Tapper, William, Aittomäki, Kristiina, Greco, Dario, Heikkinen, Tuomas, Muranen, Taru A., Fasching, Peter A., Janni, Wolfgang, Weinshilboum, Richard, Loehberg, Christian R., Hopper, John L., Southey, Melissa C., Keeman, Renske, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Chenevix-Trench, Georgia, Investigators, kConFab, Lambrechts, Diether, Wildiers, Hans, Chang-Claude, Jenny, Seibold, Petra, Couch, Fergus J., Olson, Janet E., Andrulis, Irene L., Knight, Julia A., García-Closas, Montserrat, Figueroa, Jonine, Hooning, Maartje J., Jager, Agnes, Shah, Mitul, Perkins, Barbara J., Luben, Robert, Hamann, Ute, Kabisch, Maria, Czene, Kamila, Hall, Per, Easton, Douglas F., Pharoah, Paul D.P., Liu, Jianjun, Eccles, Diana, Blomqvist, Carl, Nevanlinna, Heli
Published 2015

Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis

by Sobral-Leite, Marcelo, Wesseling, Jelle, Smit, Vincent T. H. B. M., Nevanlinna, Heli, van Miltenburg, Martine H., Sanders, Joyce, Hofland, Ingrid, Blows, Fiona M., Coulson, Penny, Patrycja, Gazinska, Schellens, Jan H. M., Fagerholm, Rainer, Heikkilä, Päivi, Aittomäki, Kristiina, Blomqvist, Carl, Provenzano, Elena, Ali, Hamid Raza, Figueroa, Jonine, Sherman, Mark, Lissowska, Jolanta, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Phillips, Kelly-Anne, Couch, Fergus J., Olson, Janet E., Vachon, Celine, Visscher, Daniel, Brenner, Hermann, Butterbach, Katja, Arndt, Volker, Holleczek, Bernd, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van Deurzen, Carolien H. M., van de Water, Bob, Broeks, Annegien, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Easton, Douglas F., Pharoah, Paul D. P., García-Closas, Montserrat, de Graauw, Marjo, Schmidt, Marjanka K.
Published 2015

Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium

by Howat, William J, Blows, Fiona M, Provenzano, Elena, Brook, Mark N, Morris, Lorna, Gazinska, Patrycja, Johnson, Nicola, McDuffus, Leigh‐Anne, Miller, Jodi, Sawyer, Elinor J, Pinder, Sarah, van Deurzen, Carolien H M, Jones, Louise, Sironen, Reijo, Visscher, Daniel, Caldas, Carlos, Daley, Frances, Coulson, Penny, Broeks, Annegien, Sanders, Joyce, Wesseling, Jelle, Nevanlinna, Heli, Fagerholm, Rainer, Blomqvist, Carl, Heikkilä, Päivi, Ali, H Raza, Dawson, Sarah‐Jane, Figueroa, Jonine, Lissowska, Jolanta, Brinton, Louise, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli‐Matti, Cox, Angela, Brock, Ian W, Cross, Simon S, Reed, Malcolm W, Couch, Fergus J, Olson, Janet E, Devillee, Peter, Mesker, Wilma E, Seyaneve, Caroline M, Hollestelle, Antoinette, Benitez, Javier, Perez, Jose Ignacio Arias, Menéndez, Primitiva, Bolla, Manjeet K, Easton, Douglas F, Schmidt, Marjanka K, Pharoah, Paul D, Sherman, Mark E, García‐Closas, Montserrat
Published 2014

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer

by Fagerholm, Rainer, Khan, Sofia, Schmidt, Marjanka K., GarcClosas, Montserrat, Heikkilä, Päivi, Saarela, Jani, Beesley, Jonathan, Jamshidi, Maral, Aittomäki, Kristiina, Liu, Jianjun, Raza Ali, H., Andrulis, Irene L., Beckmann, Matthias W., Behrens, Sabine, Blows, Fiona M., Brenner, Hermann, Chang-Claude, Jenny, Couch, Fergus J., Czene, Kamila, Fasching, Peter A., Figueroa, Jonine, Floris, Giuseppe, Glendon, Gord, Guo, Qi, Hall, Per, Hallberg, Emily, Hamann, Ute, Holleczek, Bernd, Hooning, Maartje J., Hopper, John L., Jager, Agnes, Kabisch, Maria, Investigators, kConFab/AOCS, Keeman, Renske, Kosma, Veli-Matti, Lambrechts, Diether, Lindblom, Annika, Mannermaa, Arto, Margolin, Sara, Provenzano, Elena, Shah, Mitul, Southey, Melissa C., Dennis, Joe, Lush, Michael, Michailidou, Kyriaki, Wang, Qin, Bolla, Manjeet K., Dunning, Alison M., Easton, Douglas F., Pharoah, Paul D.P ., Chenevix-Trench, Georgia, Blomqvist, Carl, Nevanlinna, Heli
Published 2017

SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival

by Jamshidi, Maral, Fagerholm, Rainer, Khan, Sofia, Aittomäki, Kristiina, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Andrulis, Irene L., Chang-Claude, Jenny, Devilee, Peter, Fasching, Peter A., Michailidou, Kyriaki, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Guo, Qi, Rhenius, Valerie, Cornelissen, Sten, Rudolph, Anja, Knight, Julia A., Loehberg, Christian R., Burwinkel, Barbara, Marme, Frederik, Hopper, John L., Southey, Melissa C., Bojesen, Stig E., Flyger, Henrik, Brenner, Hermann, Holleczek, Bernd, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Dyck, Laurien Van, Nevelsteen, Ines, Couch, Fergus J., Olson, Janet E., Giles, Graham G., McLean, Catriona, Haiman, Christopher A., Henderson, Brian E., Winqvist, Robert, Pylkäs, Katri, Tollenaar, Rob A.E.M., García-Closas, Montserrat, Figueroa, Jonine, Hooning, Maartje J., Martens, John W.M., Cox, Angela, Cross, Simon S., Simard, Jacques, Dunning, Alison M., Easton, Douglas F., Pharoah, Paul D.P., Hall, Per, Blomqvist, Carl, Schmidt, Marjanka K., Nevanlinna, Heli
Published 2015

Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association...

by Lei, Jieping, Rudolph, Anja, Moysich, Kirsten B., Behrens, Sabine, Goode, Ellen L., Bolla, Manjeet K., Dennis, Joe, Dunning, Alison M., Easton, Douglas F., Wang, Qin, Benitez, Javier, Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Fasching, Peter A., Haeberle, Lothar, Peto, Julian, dos-Santos-Silva, Isabel, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara, Marmé, Frederik, Guénel, Pascal, Truong, Thérèse, Bojesen, Stig E., Flyger, Henrik, Nielsen, Sune F., Nordestgaard, Børge G., González-Neira, Anna, Menéndez, Primitiva, Anton-Culver, Hoda, Neuhausen, Susan L., Brenner, Hermann, Arndt, Volker, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Hamann, Ute, Nevanlinna, Heli, Fagerholm, Rainer, Dörk, Thilo, Bogdanova, Natalia V., Mannermaa, Arto, Hartikainen, Jaana M., Van Dijck, Laurien, Smeets, Ann, Flesch-Janys, Dieter, Eilber, Ursula, Radice, Paolo, Peterlongo, Paolo, Couch, Fergus J., Hallberg, Emily, Giles, Graham G., Milne, Roger L., Haiman, Christopher A., Schumacher, Fredrick, Simard, Jacques, Goldberg, Mark S., Kristensen, Vessela, Borresen-Dale, Anne-Lise, Zheng, Wei, Beeghly-Fadiel, Alicia, Winqvist, Robert, Grip, Mervi, Andrulis, Irene L., Glendon, Gord, García-Closas, Montserrat, Figueroa, Jonine, Czene, Kamila, Brand, Judith S., Darabi, Hatef, Eriksson, Mikael, Hall, Per, Li, Jingmei, Cox, Angela, Cross, Simon S., Pharoah, Paul D. P., Shah, Mitul, Kabisch, Maria, Torres, Diana, Jakubowska, Anna, Lubinski, Jan, Ademuyiwa, Foluso, Ambrosone, Christine B., Swerdlow, Anthony, Jones, Michael, Chang-Claude, Jenny
Published 2015

Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

by Garcia-Closas, Montserrat, Hall, Per, Nevanlinna, Heli, Pooley, Karen, Morrison, Jonathan, Richesson, Douglas A., Bojesen, Stig E., Nordestgaard, Børge G., Axelsson, Christen K., Arias, Jose I., Milne, Roger L., Ribas, Gloria, González-Neira, Anna, Benítez, Javier, Zamora, Pilar, Brauch, Hiltrud, Justenhoven, Christina, Hamann, Ute, Ko, Yon-Dschun, Bruening, Thomas, Haas, Susanne, Dörk, Thilo, Schürmann, Peter, Hillemanns, Peter, Bogdanova, Natalia, Bremer, Michael, Karstens, Johann Hinrich, Fagerholm, Rainer, Aaltonen, Kirsimari, Aittomäki, Kristiina, von Smitten, Karl, Blomqvist, Carl, Mannermaa, Arto, Uusitupa, Matti, Eskelinen, Matti, Tengström, Maria, Kosma, Veli-Matti, Kataja, Vesa, Chenevix-Trench, Georgia, Spurdle, Amanda B., Beesley, Jonathan, Chen, Xiaoqing, Australian Ovarian Cancer Management Group, The Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Devilee, Peter, van Asperen, Christi J., Jacobi, Catharina E., Tollenaar, Rob A. E. M., Huijts, Petra E.A., Klijn, Jan G. M., Chang-Claude, Jenny, Kropp, Silke, Slanger, Tracy, Flesch-Janys, Dieter, Mutschelknauss, Elke, Salazar, Ramona, Wang-Gohrke, Shan, Couch, Fergus, Goode, Ellen L., Olson, Janet E., Vachon, Celine, Fredericksen, Zachary S., Giles, Graham G., Baglietto, Laura, Severi, Gianluca, Hopper, John L., English, Dallas R., Southey, Melissa C., Haiman, Christopher A., Henderson, Brian E., Kolonel, Laurence N., Le Marchand, Loic, Stram, Daniel O., Hunter, David J., Hankinson, Susan E., Cox, David G., Tamimi, Rulla, Kraft, Peter, Sherman, Mark E., Chanock, Stephen J., Lissowska, Jolanta, Brinton, Louise A., Peplonska, Beata, Klijn, Jan G. M., Hooning, Maartje J., Meijers-Heijboer, Han, Collee, J. Margriet, van den Ouweland, Ans, Uitterlinden, Andre G., Liu, Jianjun, Lin, Low Yen, Yuqing, Li, Humphreys, Keith, Czene, Kamila, Cox, Angela, Balasubramanian, Sabapathy P., Cross, Simon S., Reed, Malcolm W. R., Blows, Fiona, Driver, Kristy, Dunning, Alison, Tyrer, Jonathan, Ponder, Bruce A. J., Sangrajrang, Suleeporn, Brennan, Paul, McKay, James, Odefrey, Fabrice, Gabrieau, Valerie, Sigurdson, Alice, Doody, Michele, Struewing, Jeffrey P., Alexander, Bruce, Easton, Douglas F., Pharoah, Paul D.
Published 2008