Combination drug screen targeting glioblastoma core vulnerabilities reveals pharmacological synergisms

por Ariey-Bonnet, Jérémy, Berges, Raphael, Montero, Marie-Pierre, Mouysset, Baptiste, Piris, Patricia, Muller, Kevin, Pinna, Guillaume, Failes, Tim W., Arndt, Greg M., Morando, Philippe, Baeza-Kallee, Nathalie, Colin, Carole, Chinot, Olivier, Braguer, Diane, Morelli, Xavier, André, Nicolas, Carré, Manon, Tabouret, Emeline, Figarella-Branger, Dominique, Le Grand, Marion, Pasquier, Eddy
Publicado 2023

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

por Somers, Klaartje, Wen, Victoria W., Middlemiss, Shiloh M. C., Osborne, Brenna, Forgham, Helen, Jung, MoonSun, Karsa, Mawar, Clifton, Molly, Bongers, Angelika, Gao, Jixuan, Mayoh, Chelsea, Raoufi-Rad, Newsha, Kusnadi, Eric P., Hannan, Kate M., Scott, David A., Kwek, Alan, Liu, Bing, Flemming, Claudia, Chudakova, Daria A., Pandher, Ruby, Failes, Tim W., Lim, James, Angeli, Andrea, Osterman, Andrei L., Imamura, Toshihiko, Kees, Ursula R., Supuran, Claudiu T., Pearson, Richard B., Hannan, Ross D., Davis, Thomas P., McCarroll, Joshua, Kavallaris, Maria, Turner, Nigel, Gudkov, Andrei V., Haber, Michelle, Norris, Murray D., Henderson, Michelle J.
Publicado 2019

In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer

por Lau, Loretta M S, Mayoh, Chelsea, Xie, Jinhan, Barahona, Paulette, MacKenzie, Karen L, Wong, Marie, Kamili, Alvin, Tsoli, Maria, Failes, Tim W, Kumar, Amit, Mould, Emily V A, Gifford, Andrew, Chow, Shu‐Oi, Pinese, Mark, Fletcher, Jamie I, Arndt, Greg M, Khuong‐Quang, Dong‐Anh, Wadham, Carol, Batey, Daniel, Eden, Georgina, Trebilcock, Peter, Joshi, Swapna, Alfred, Stephanie, Gopalakrishnan, Anjana, Khan, Aaminah, Grebert Wade, Dylan, Strong, Patrick A, Manouvrier, Elodie, Morgan, Lisa T, Span, Miriam, Lim, Jin Yi, Cadiz, Roxanne, Ung, Caitlin, Thomas, David M, Tucker, Katherine M, Warby, Meera, McCowage, Geoffrey B, Dalla‐Pozza, Luciano, Byrne, Jennifer A, Saletta, Federica, Fellowes, Andrew, Fox, Stephen B, Norris, Murray D, Tyrrell, Vanessa, Trahair, Toby N, Lock, Richard B, Cowley, Mark J, Ekert, Paul G, Haber, Michelle, Ziegler, David S, Marshall, Glenn M
Publicado 2021