Fine mapping genetic determinants of the highly variably expressed MHC gene ZFP57

por Plant, Katharine, Fairfax, Benjamin P, Makino, Seiko, Vandiedonck, Claire, Radhakrishnan, Jayachandran, Knight, Julian C
Publicado 2014

EPISPOT: An epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies

por Ruffieux, Hélène, Fairfax, Benjamin P., Nassiri, Isar, Vigorito, Elena, Wallace, Chris, Richardson, Sylvia, Bottolo, Leonardo
Publicado 2021

Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination

por Pischedda, Sara, O’Connor, Daniel, Fairfax, Benjamin P., Salas, Antonio, Martinon-Torres, Federico, Pollard, Andrew J., Trück, Johannes
Publicado 2021

An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6

por Fairfax, Benjamin P., Vannberg, Fredrik O., Radhakrishnan, Jayachandran, Hakonarson, Hakon, Keating, Brendan J., Hill, Adrian V.S., Knight, Julian C.
Publicado 2010

Genomic modulators of gene expression in human neutrophils

por Naranbhai, Vivek, Fairfax, Benjamin P., Makino, Seiko, Humburg, Peter, Wong, Daniel, Ng, Esther, Hill, Adrian V. S., Knight, Julian C.
Publicado 2015

Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach

por Wong, Daniel, Lee, Wanseon, Humburg, Peter, Makino, Seiko, Lau, Evelyn, Naranbhai, Vivek, Fairfax, Benjamin P, Chan, Kenneth, Plant, Katharine, Knight, Julian C
Publicado 2014

GENETICS OF GENE EXPRESSION IN PRIMARY IMMUNE CELLS IDENTIFIES CELL-SPECIFIC MASTER REGULATORS AND ROLES OF HLA ALLELES

por Fairfax, Benjamin P, Makino, Seiko, Radhakrishnan, Jayachandran, Plant, Katharine, Leslie, Stephen, Dilthey, Alexander, Ellis, Peter, Langford, Cordelia, Vannberg, Fredrik O, Knight, Julian C
Publicado 2012

Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes

por Naranbhai, Vivek, Fletcher, Helen A., Tanner, Rachel, O'Shea, Matthew K., McShane, Helen, Fairfax, Benjamin P., Knight, Julian C., Hill, Adrian V.S.
Publicado 2015

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4(+) versus CD8(+) T cells

por Kasela, Silva, Kisand, Kai, Tserel, Liina, Kaleviste, Epp, Remm, Anu, Fischer, Krista, Esko, Tõnu, Westra, Harm-Jan, Fairfax, Benjamin P., Makino, Seiko, Knight, Julian C., Franke, Lude, Metspalu, Andres, Peterson, Pärt, Milani, Lili
Publicado 2017

Whole-genome sequencing identifies homozygous BRCA2 deletion guiding treatment in dedifferentiated prostate cancer

por Purshouse, Karin, Schuh, Anna, Fairfax, Benjamin P., Knight, Sam, Antoniou, Pavlos, Dreau, Helene, Popitsch, Niko, Gatter, Kevin, Roberts, Ian, Browning, Lisa, Traill, Zoe, Kerr, David, Verrill, Clare, Tuthill, Mark, Taylor, Jenny C., Protheroe, Andrew
Publicado 2017

IFNγ signaling in cytotoxic T cells restricts anti-tumor responses by inhibiting the maintenance and diversity of intra-tumoral stem-like T cells

por Mazet, Julie M., Mahale, Jagdish N., Tong, Orion, Watson, Robert A., Lechuga‐Vieco, Ana Victoria, Pirgova, Gabriela, Lau, Vivian W. C., Attar, Moustafa, Koneva, Lada A., Sansom, Stephen N., Fairfax, Benjamin P., Gérard, Audrey
Publicado 2023

Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma

por Fairfax, Benjamin P, Taylor, Chelsea A, Watson, Robert A, Nassiri, Isar, Danielli, Sara, Fang, Hai, Mahé, Elise A, Cooper, Rosalin, Woodcock, Victoria, Traill, Zoe, Al-Mossawi, M Hussein, Knight, Julian C, Klenerman, Paul, Payne, Miranda, Middleton, Mark R
Publicado 2020

Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele

por Al-Mossawi, Hussein, Yager, Nicole, Taylor, Chelsea A., Lau, Evelyn, Danielli, Sara, de Wit, Jelle, Gilchrist, James, Nassiri, Isar, Mahe, Elise A., Lee, Wanseon, Rizvi, Laila, Makino, Seiko, Cheeseman, Jane, Neville, Matt, Knight, Julian C., Bowness, Paul, Fairfax, Benjamin P.
Publicado 2019

Su1185 IMMUNE CHECKPOINT INHIBITOR-RELATED COLITIS ASSESSMENT AND PROGNOSIS: CAN UCEIS, MAYO AND NANCY INDEX SCORING POINT THE WAY?

por Cheung, Vincent T., Gupta, Tarun, Olsson-Brown, Anna C., Subramanian, Sreedhar, Sasson, Sarah C., Heseltine, Jonathan, Fryer, Eve, Collantes-Bellido, Elena, Sacco, Joseph J., Pirmohamed, Munir, Simmons, Alison, Klenerman, Paul, Fairfax, Benjamin P., Payne, Miranda J., Middleton, Mark R., Brain, Oliver
Publicado 2020

Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

por Ye, Weiyu, Olsson-Brown, Anna, Watson, Robert A., Cheung, Vincent T. F., Morgan, Robert D., Nassiri, Isar, Cooper, Rosalin, Taylor, Chelsea A., Akbani, Umair, Brain, Oliver, Matin, Rubeta N., Coupe, Nicholas, Middleton, Mark R., Coles, Mark, Sacco, Joseph J., Payne, Miranda J., Fairfax, Benjamin P.
Publicado 2021

Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity

por Gilchrist, James J., Makino, Seiko, Naranbhai, Vivek, Sharma, Piyush K., Koturan, Surya, Tong, Orion, Taylor, Chelsea A., Watson, Robert A., de los Aires, Alba Verge, Cooper, Rosalin, Lau, Evelyn, Danielli, Sara, Hameiri-Bowen, Dan, Lee, Wanseon, Ng, Esther, Whalley, Justin, Knight, Julian C., Fairfax, Benjamin P.
Publicado 2022

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

por Bentham, James, Morris, David L, Graham, Deborah S Cunninghame, Pinder, Christopher L, Tombleson, Philip, Behrens, Timothy W, Martín, Javier, Fairfax, Benjamin P, Knight, Julian C, Chen, Lingyan, Replogle, Joseph, Syvänen, Ann-Christine, Rönnblom, Lars, Graham, Robert R, Wither, Joan E, Rioux, John D, Alarcón-Riquelme, Marta E, Vyse, Timothy J
Publicado 2015

Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia

por Simpson, Nuala H, Addis, Laura, Brandler, William M, Slonims, Vicky, Clark, Ann, Watson, Jocelynne, Scerri, Thomas S, Hennessy, Elizabeth R, Bolton, Patrick F, Conti-Ramsden, Gina, Fairfax, Benjamin P, Knight, Julian C, Stein, John, Talcott, Joel B, O'Hare, Anne, Baird, Gillian, Paracchini, Silvia, Fisher, Simon E, Newbury, Dianne F, Consortium, SLI
Publicado 2014

Genome-wide association study of leprosy in Malawi and Mali

por Gilchrist, James J., Auckland, Kathryn, Parks, Tom, Mentzer, Alexander J., Goldblatt, Lily, Naranbhai, Vivek, Band, Gavin, Rockett, Kirk A., Toure, Ousmane B., Konate, Salimata, Sissoko, Sibiri, Djimdé, Abdoulaye A., Thera, Mahamadou A., Doumbo, Ogobara K., Sow, Samba, Floyd, Sian, Pönnighaus, Jörg M., Warndorff, David K., Crampin, Amelia C., Fine, Paul E. M., Fairfax, Benjamin P., Hill, Adrian V. S.
Publicado 2022

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

por Gilchrist, James J., Rautanen, Anna, Fairfax, Benjamin P., Mills, Tara C., Naranbhai, Vivek, Trochet, Holly, Pirinen, Matti, Muthumbi, Esther, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, Msefula, Chisomo L., Gondwe, Esther N., MacLennan, Jenny M., Chapman, Stephen J., Molyneux, Malcolm E., Knight, Julian C., Spencer, Chris C. A., Williams, Thomas N., MacLennan, Calman A., Scott, J. Anthony G., Hill, Adrian V. S.
Publicado 2018