Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays

por Wong, C, Anderson, D J, Lee, E F, Fairlie, W D, Ludlam, M J C
Publicado 2012

A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo

por Lee, E F, Takiguchi, M, Pettikiriarachchi, A, Evangelista, M, Huang, D C S, Dickins, R A, Fairlie, W D
Publicado 2015

Increase in upper tropospheric and lower stratospheric aerosol levels and its potential connection with Asian pollution

por Vernier, J-P, Fairlie, T D, Natarajan, M, Wienhold, F G, Bian, J, Martinsson, B G, Crumeyrolle, S, Thomason, L W, Bedka, K M
Publicado 2015

Induction of endoplasmic reticulum stress is associated with the anti‐tumor activity of monepantel across cancer types

por Harris, Tiffany J., Liao, Yang, Shi, Wei, Evangelista, Marco, Pal, Bhupinder, Puthalakath, Hamsa, Aston, Roger, Mollard, Richard, Mariadason, John M., Lee, Erinna F., Fairlie, Walter D.
Publicado 2023

Characterisation of a novel A1-specific monoclonal antibody

por Lang, M J, Brennan, M S, O'Reilly, L A, Ottina, E, Czabotar, P E, Whitlock, E, Fairlie, W D, Tai, L, Strasser, A, Herold, M J
Publicado 2014

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins

por Mérino, Delphine, Giam, Maybelline, Hughes, Peter D., Siggs, Owen M., Heger, Klaus, O'Reilly, Lorraine A., Adams, Jerry M., Strasser, Andreas, Lee, Erinna F., Fairlie, Walter D., Bouillet, Philippe
Publicado 2009

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax

por Hockings, C, Anwari, K, Ninnis, R L, Brouwer, J, O'Hely, M, Evangelista, M, Hinds, M G, Czabotar, P E, Lee, E F, Fairlie, W D, Dewson, G, Kluck, R M
Publicado 2015

A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma

por Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Jenkins, Laura J., Poh, Ashleigh R., Walkiewicz, Marzena, Leong, Trishe, Mariadason, John M., Cebon, Jonathan, Balachander, Srividya B., Cidado, Justin R., Lee, Erinna F., John, Thomas, Fairlie, Walter D.
Publicado 2021

BCL-XL is an actionable target for treatment of malignant pleural mesothelioma

por Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Harris, Tiffany J., Steinohrt, Nikita S., Jenkins, Laura J., Walkiewicz, Marzena, O’Donoghue, Robert J. J., Poh, Ashleigh R., Thapa, Bibhusal, Williams, David S., Leong, Trishe, Mariadason, John M., Li, Xia, Cebon, Jonathan, Lee, Erinna F., John, Thomas, Fairlie, W. D.
Publicado 2020

MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib

por Young, Adelaide I. J., Law, Andrew M. K., Castillo, Lesley, Chong, Sabrina, Cullen, Hayley D., Koehler, Martin, Herzog, Sebastian, Brummer, Tilman, Lee, Erinna F., Fairlie, Walter D., Lucas, Morghan C., Herrmann, David, Allam, Amr, Timpson, Paul, Watkins, D. Neil, Millar, Ewan K. A., O’Toole, Sandra A., Gallego-Ortega, David, Ormandy, Christopher J., Oakes, Samantha R.
Publicado 2016