The Onconeural Antigen cdr2 Is a Novel APC/C Target that Acts in Mitosis to Regulate C-Myc Target Genes in Mammalian Tumor Cells

por O'Donovan, Kevin J., Diedler, Jennifer, Couture, Graeme C., Fak, John J., Darnell, Robert B.
Publicado 2010

Differential 3’ processing of specific transcripts expands regulatory and protein diversity across neuronal cell types

por Jereb, Saša, Hwang, Hun-Way, Van Otterloo, Eric, Govek, Eve-Ellen, Fak, John J, Yuan, Yuan, Hatten, Mary E, Darnell, Robert B
Publicado 2018

FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons

por Hale, Caryn R, Sawicka, Kirsty, Mora, Kevin, Fak, John J, Kang, Jin Joo, Cutrim, Paula, Cialowicz, Katarzyna, Carroll, Thomas S, Darnell, Robert B
Publicado 2021

miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity

por Moore, Michael J., Scheel, Troels K. H., Luna, Joseph M., Park, Christopher Y., Fak, John J., Nishiuchi, Eiko, Rice, Charles M., Darnell, Robert B.
Publicado 2015

m(6)A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

por Ke, Shengdong, Pandya-Jones, Amy, Saito, Yuhki, Fak, John J., Vågbø, Cathrine Broberg, Geula, Shay, Hanna, Jacob H., Black, Douglas L., Darnell, James E., Darnell, Robert B.
Publicado 2017

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity

por Moore, Michael J, Blachere, Nathalie E, Fak, John J, Park, Christopher Y, Sawicka, Kirsty, Parveen, Salina, Zucker-Scharff, Ilana, Moltedo, Bruno, Rudensky, Alexander Y, Darnell, Robert B
Publicado 2018

FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

por Sawicka, Kirsty, Hale, Caryn R, Park, Christopher Y, Fak, John J, Gresack, Jodi E, Van Driesche, Sarah J, Kang, Jin Joo, Darnell, Jennifer C, Darnell, Robert B
Publicado 2019

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

por Licatalosi, Donny D., Mele, Aldo, Fak, John J., Ule, Jernej, Kayikci, Melis, Chi, Sung Wook, Clark, Tyson A., Schweitzer, Anthony C., Blume, John E., Wang, Xuning, Darnell, Jennifer C., Darnell, Robert B.
Publicado 2008

NOVA2-mediated RNA regulation is required for axonal pathfinding during development

por Saito, Yuhki, Miranda-Rottmann, Soledad, Ruggiu, Matteo, Park, Christopher Y, Fak, John J, Zhong, Ru, Duncan, Jeremy S, Fabella, Brian A, Junge, Harald J, Chen, Zhe, Araya, Roberto, Fritzsch, Bernd, Hudspeth, A J, Darnell, Robert B
Publicado 2016

A majority of m(6)A residues are in the last exons, allowing the potential for 3′ UTR regulation

por Ke, Shengdong, Alemu, Endalkachew A., Mertens, Claudia, Gantman, Emily Conn, Fak, John J., Mele, Aldo, Haripal, Bhagwattie, Zucker-Scharff, Ilana, Moore, Michael J., Park, Christopher Y., Vågbø, Cathrine Broberg, Kusśnierczyk, Anna, Klungland, Arne, Darnell, James E., Darnell, Robert B.
Publicado 2015