UGT concentrations in human rectal tissue after multidose, oral curcumin

por Asher, Gary N., Fallon, John K., Smith, Philip C.
Publicado 2016

Formation of CYP3A‐specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β‐hydroxycholesterol/cholesterol ratio

por Lee, Jonghwa, Fallon, John K., Smith, Philip C., Jackson, Klarissa D.
Publicado 2022

Extreme low dose of 5-fluorouracil reverses MDR in cancer by sensitizing cancer associated fibroblasts and down-regulating P-gp

por Ma, Yan, Wang, Yuhua, Xu, Zhenghong, Wang, Yongjun, Fallon, John K., Liu, Feng
Publicado 2017

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

por Speer, Jennifer E., Wang, Yuli, Fallon, John K., Smith, Philip C., Allbritton, Nancy L.
Publicado 2019

New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer

por MA, YAN, LIN, ZHIQIANG, FALLON, JOHN K., ZHAO, QIANG, LIU, DAN, WANG, YONGJUN, LIU, FENG
Publicado 2015

Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2(−/−) Mice

por Morse, Bridget L., Chen, Lisa Hong, Catlow, John T., Fallon, John K., Smith, Philip C., Hillgren, Kathleen M.
Publicado 2021

A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity

por Saran, Chitra, Fu, Dong, Ho, Henry, Klein, Abigail, Fallon, John K., Honkakoski, Paavo, Brouwer, Kim L. R.
Publicado 2022

Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes

por Fashe, Muluneh M., Fallon, John K., Miner, Taryn A., Tiley, Jacqueline B., Smith, Philip C., Lee, Craig R.
Publicado 2022

Combinational Delivery of Hydrophobic and Hydrophilic Anticancer Drugs in Single Nanoemulsions To Treat MDR in Cancer

por Ma, Yan, Liu, Dan, Wang, Dun, Wang, Yongjun, Fu, Qiang, Fallon, John K., Yang, Xinggang, He, Zhonggui, Liu, Feng
Publicado 2014

Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam

por Fashe, Muluneh M., Miner, Taryn A., Fallon, John K., Schauer, Amanda P., Sykes, Craig, Smith, Philip C., Lee, Craig R.
Publicado 2023

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues

por Hammid, Anam, Fallon, John K., Lassila, Toni, Salluce, Giulia, Smith, Philip C., Tolonen, Ari, Sauer, Achim, Urtti, Arto, Honkakoski, Paavo
Publicado 2021

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

por Speer, Jennifer E., Gunasekara, Dulan B., Wang, Yuli, Fallon, John K., Attayek, Peter J., Smith, Philip C., Sims, Christopher E., Allbritton, Nancy L.
Publicado 2019

A phase I evaluation of the effect of curcumin on dose‐limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors

por Gbolahan, Olumide B., O’Neil, Bert H., McRee, Autumn J., Sanoff, Hanna K., Fallon, John K., Smith, Philip C., Ivanova, Anastasia, Moore, Dominic T., Dumond, Julie, Asher, Gary N.
Publicado 2022

Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease

por Zhao, Yuling, Haney, Matthew J., Fallon, John K., Rodriguez, Myosotys, Swain, Carson J., Arzt, Camryn J., Smith, Philip C., Loop, Matthew Shane, Harrison, Emily B., El-Hage, Nazira, Batrakova, Elena V.
Publicado 2022

Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines

por Wang, Yongjun, Liu, Dan, Zheng, Qingchuan, Zhao, Qiang, Zhang, Hongjuan, Ma, Yan, Fallon, John K., Fu, Qiang, Haynes, Matthew T., Lin, Guimei, Zhang, Rong, Wang, Dun, Yang, Xinggang, Zhao, Linxiang, He, Zhonggui, Liu, Feng
Publicado 2014

Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes

por Khatri, Raju, Fallon, John K., Sykes, Craig, Kulick, Natasha, Rementer, Rebecca J. B., Miner, Taryn A., Schauer, Amanda P., Kashuba, Angela D. M., Boggess, Kim A., Brouwer, Kim L. R., Smith, Philip C., Lee, Craig R.
Publicado 2021