Effective holistic characterization of small molecule effects using heterogeneous biological networks

por Mangione, William, Falls, Zackary, Samudrala, Ram
Publicado 2023

Optimal COVID-19 therapeutic candidate discovery using the CANDO platform

por Mangione, William, Falls, Zackary, Samudrala, Ram
Publicado 2022

Exploration of interaction scoring criteria in the CANDO platform

por Falls, Zackary, Mangione, William, Schuler, James, Samudrala, Ram
Publicado 2019

A Deep-Learning Proteomic-Scale Approach for Drug Design

por Overhoff, Brennan, Falls, Zackary, Mangione, William, Samudrala, Ram
Publicado 2021

Accurate Prediction of Inhibitor Binding to HIV-1 Protease Using CANDOCK

por Falls, Zackary, Fine, Jonathan, Chopra, Gaurav, Samudrala, Ram
Publicado 2022

Shotgun drug repurposing biotechnology to tackle epidemics and pandemics

por Mangione, William, Falls, Zackary, Melendy, Thomas, Chopra, Gaurav, Samudrala, Ram
Publicado 2020

Shotgun drug repurposing biotechnology to tackle epidemics and pandemics

por Mangione, William, Falls, Zackary, Melendy, Thomas, Chopra, Gaurav, Samudrala, Ram
Publicado 2020

352 Computational methods for predicting drug combinations for targeting KRAS mutations relevant to non-small cell lung cancer

por Bruggemann, Liana, Falls, Zackary, Mangione, William, Mahajan, Supriya, Samudrala, Ram
Publicado 2022

Association of C>U RNA Editing with Human Disease Variants

por MANDLOI, Sapan, FALLS, Zackary, DENG, Rong, SAMUDRALA, Ram, ELKIN, Peter L.
Publicado 2020

Evaluating the performance of drug-repurposing technologies

por Schuler, James, Falls, Zackary, Mangione, William, Hudson, Matthew L., Bruggemann, Liana, Samudrala, Ram
Publicado 2022

Identifying Protein Features and Pathways Responsible for Toxicity Using Machine Learning and Tox21: Implications for Predictive Toxicology

por Moukheiber, Lama, Mangione, William, Moukheiber, Mira, Maleki, Saeed, Falls, Zackary, Gao, Mingchen, Samudrala, Ram
Publicado 2022

The Role of C-to-U RNA Editing in Human Biodiversity

por Van Norden, Melissa, Falls, Zackary, Mandloi, Sapan, Segal, Brahm, Baysal, Bora, Samudrala, Ram, Elkin, Peter L.
Publicado 2023

A fluorescence-based, gain-of-signal, live cell system to evaluate SARS-CoV-2 main protease inhibition

por Dey-Rao, Rama, Smith, George R., Timilsina, Uddhav, Falls, Zackary, Samudrala, Ram, Stavrou, Spyridon, Melendy, Thomas
Publicado 2021

Multiscale Analysis and Validation of Effective Drug Combinations Targeting Driver KRAS Mutations in Non-Small Cell Lung Cancer

por Bruggemann, Liana, Falls, Zackary, Mangione, William, Schwartz, Stanley A., Battaglia, Sebastiano, Aalinkeel, Ravikumar, Mahajan, Supriya D., Samudrala, Ram
Publicado 2023

Proteomic Network Analysis of Bronchoalveolar Lavage Fluid in Ex-Smokers to Discover Implicated Protein Targets and Novel Drug Treatments for Chronic Obstructive Pulmonary Disease

por Mammen, Manoj J., Tu, Chengjian, Morris, Matthew C., Richman, Spencer, Mangione, William, Falls, Zackary, Qu, Jun, Broderick, Gordon, Sethi, Sanjay, Samudrala, Ram
Publicado 2022

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

por Palanikumar, L., Karpauskaite, Laura, Al-Sayegh, Mohamed, Chehade, Ibrahim, Alam, Maheen, Hassan, Sarah, Maity, Debabrata, Ali, Liaqat, Kalmouni, Mona, Hunashal, Yamanappa, Ahmed, Jemil, Houhou, Tatiana, Karapetyan, Shake, Falls, Zackary, Samudrala, Ram, Pasricha, Renu, Esposito, Gennaro, Afzal, Ahmed J., Hamilton, Andrew D., Kumar, Sunil, Magzoub, Mazin
Publicado 2021