The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A(1) and A(2A) receptor affinity and selectivity profil...

por Squarcialupi, Lucia, Betti, Marco, Catarzi, Daniela, Varano, Flavia, Falsini, Matteo, Ravani, Annalisa, Pasquini, Silvia, Vincenzi, Fabrizio, Salmaso, Veronica, Sturlese, Mattia, Varani, Katia, Moro, Stefano, Colotta, Vittoria
Publicado 2017

Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A(2A) Receptor

por Amelia, Tasia, van Veldhoven, Jacobus P. D., Falsini, Matteo, Liu, Rongfang, Heitman, Laura H., van Westen, Gerard J. P., Segala, Elena, Verdon, Grégory, Cheng, Robert K. Y., Cooke, Robert M., van der Es, Daan, IJzerman, Adriaan P.
Publicado 2021