Mutations in the coat protein-binding cis-acting RNA motifs debilitate RNA recombination of Brome mosaic virus

por Sztuba-Solińska, Joanna, Fanning, Sean W., Horn, James R., Bujarski, Jozef J.
Publicado 2012

Editorial: Hormone resistance in cancer

por Phoenix, John T., Budreika, Audris, Kostlan, Raymond J., Hwang, Justin H., Fanning, Sean W., Kregel, Steven
Publicado 2023

Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer

por Lainé, Muriel, Fanning, Sean W., Chang, Ya-Fang, Green, Bradley, Greene, Marianne E., Komm, Barry, Kurleto, Justyna D., Phung, Linda, Greene, Geoffrey L.
Publicado 2021

Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer

por Mayne, Christopher G., Toy, Weiyi, Carlson, Kathryn E., Bhatt, Trusha, Fanning, Sean W., Greene, Geoffrey L., Katzenellenbogen, Benita S., Chandarlapaty, Sarat, Katzenellenbogen, John A., Tajkhorshid, Emad
Publicado 2021

Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer

por Maximov, Philipp Y., Abderrahman, Balkees, Fanning, Sean W., Sengupta, Surojeet, Fan, Ping, Curpan, Ramona F., Rincon, Daniela Maria Quintana, Greenland, Jeffery A., Rajan, Shyamala S., Greene, Geoffrey L., Jordan, V. Craig
Publicado 2018

Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells

por Hosfield, David J, Weber, Sandra, Li, Nan-Sheng, Sauvage, Madline, Joiner, Carstyn F, Hancock, Govinda R, Sullivan, Emily A, Ndukwe, Estelle, Han, Ross, Cush, Sydney, Lainé, Muriel, Mader, Sylvie C, Greene, Geoffrey L, Fanning, Sean W
Publicado 2022

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

por Fanning, Sean W, Mayne, Christopher G, Dharmarajan, Venkatasubramanian, Carlson, Kathryn E, Martin, Teresa A, Novick, Scott J, Toy, Weiyi, Green, Bradley, Panchamukhi, Srinivas, Katzenellenbogen, Benita S, Tajkhorshid, Emad, Griffin, Patrick R, Shen, Yang, Chandarlapaty, Sarat, Katzenellenbogen, John A, Greene, Geoffrey L
Publicado 2016

The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells

por Maximov, Philipp Y., Abderrahman, Balkees, Hawsawi, Yousef M., Chen, Yue, Foulds, Charles E., Jain, Antrix, Malovannaya, Anna, Fan, Ping, Curpan, Ramona F., Han, Ross, Fanning, Sean W., Broom, Bradley M., Quintana Rincon, Daniela M., Greenland, Jeffery A., Greene, Geoffrey L., Jordan, V. Craig
Publicado 2020

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells

por Fanning, Sean W, Jeselsohn, Rinath, Dharmarajan, Venkatasubramanian, Mayne, Christopher G, Karimi, Mostafa, Buchwalter, Gilles, Houtman, René, Toy, Weiyi, Fowler, Colin E, Han, Ross, Lainé, Muriel, Carlson, Kathryn E, Martin, Teresa A, Nowak, Jason, Nwachukwu, Jerome C, Hosfield, David J, Chandarlapaty, Sarat, Tajkhorshid, Emad, Nettles, Kendall W, Griffin, Patrick R, Shen, Yang, Katzenellenbogen, John A, Brown, Myles, Greene, Geoffrey L
Publicado 2018

Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression

por Gamage, Hashni Epa Vidana, Shahoei, Sayyed Hamed, Albright, Samuel T., Wang, Yu, Smith, Amanda J., Farmer, Rachel, Fink, Emma C., Jacquin, Elise, Weisser, Erin, Bautista, Rafael O., Henn, Madeline A., Schane, Claire P., Nelczyk, Adam T., Ma, Liqian, Gupta, Anasuya Das, Bendre, Shruti V., Nguyen, Tiffany, Tiwari, Srishti, Krawczynska, Natalia, He, Sisi, Tjoanda, Evelyn, Chen, Hong, Sverdlov, Maria, Gann, Peter H., Boidot, Romain, Vegran, Frederique, Fanning, Sean W., Apetoh, Lionel, Hergenrother, Paul J., Nelson, Erik R.
Publicado 2023