Wild-type huntingtin regulates human macrophage function

por O’Regan, Grace C., Farag, Sahar H., Ostroff, Gary R., Tabrizi, Sarah J., Andre, Ralph
Publicado 2020

In vivo neutralization of the protagonist role of macrophages during the chronic inflammatory stage of Huntington’s disease

por Pido-Lopez, Jeffrey, Andre, Ralph, Benjamin, Agnesska C., Ali, Nadira, Farag, Sahar, Tabrizi, Sarah J., Bates, Gillian P.
Publicado 2018

Inhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington’s disease by etanercept treatment

por Pido-Lopez, Jeffrey, Tanudjojo, Benedict, Farag, Sahar, Bondulich, Marie-Katrin, Andre, Ralph, Tabrizi, Sarah J., Bates, Gillian P.
Publicado 2019

Human Huntington’s disease pluripotent stem cell-derived microglia develop normally but are abnormally hyper-reactive and release elevated levels of reactive oxygen species

por O’Regan, Grace C., Farag, Sahar H., Casey, Caroline S., Wood-Kaczmar, Alison, Pocock, Jennifer M., Tabrizi, Sarah J., Andre, Ralph
Publicado 2021

Mislocalization of Nucleocytoplasmic Transport Proteins in Human Huntington’s Disease PSC-Derived Striatal Neurons

por Lange, Jenny, Wood-Kaczmar, Alison, Ali, Aneesa, Farag, Sahar, Ghosh, Rhia, Parker, Jennifer, Casey, Caroline, Uno, Yumiko, Kunugi, Akiyoshi, Ferretti, Patrizia, Andre, Ralph, Tabrizi, Sarah J.
Publicado 2021