Lipid droplets go nuclear

por Farese, Robert V., Walther, Tobias C.
Publicado 2016

Atypical PKC: therapeutic target for Alzheimer’s?

por Farese, Robert V., Sajan, Mini P.
Publicado 2018

Balancing the fat: lipid droplets and human disease

por Krahmer, Natalie, Farese, Robert V, Walther, Tobias C
Publicado 2013

The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes

por Chitraju, Chandramohan, Walther, Tobias C., Farese, Robert V.
Publicado 2019

Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus

por Farese, Robert V., Lee, Mackenzie C., Sajan, Mini P.
Publicado 2014

MicroRNA-29b Regulates the Expression Level of Human Progranulin, a Secreted Glycoprotein Implicated in Frontotemporal Dementia

por Jiao, Jian, Herl, Lauren D., Farese, Robert V., Gao, Fen-Biao
Publicado 2010

Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

por Chitraju, Chandramohan, Fischer, Alexander W., Farese, Robert V., Walther, Tobias C.
Publicado 2020

Conditional targeting of phosphatidylserine decarboxylase to lipid droplets

por Kumar, Santosh, Chitraju, Chandramohan, Farese, Robert V., Walther, Tobias C., Burd, Christopher G.
Publicado 2021

Pharmacological TLR4 Inhibition Protects against Acute and Chronic Fat-Induced Insulin Resistance in Rats

por Zhang, Ning, Liang, Hanyu, Farese, Robert V., Li, Ji, Musi, Nicolas, Hussey, Sophie E.
Publicado 2015

Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin‐resistant forms of obesity and type 2 diabetes mellitus

por Sajan, Mini P., Hansen, Barbara C., Acevedo‐Duncan, Mildred, Kindy, Mark S., Cooper, Denise R., Farese, Robert V.
Publicado 2021

Efficient Hepatitis C Virus Particle Formation Requires Diacylglycerol Acyltransferase 1 (DGAT1)

por Herker, Eva, Harris, Charles, Hernandez, Céline, Carpentier, Arnaud, Kaehlcke, Katrin, Rosenberg, Arielle R., Farese, Robert V., Ott, Melanie
Publicado 2010

Impairment of insulin-stimulated glucose transport and ERK activation by adipocyte-specific knockout of PKC-λ produces a phenotype characterized by diminished adiposity and enhance...

por Sajan, Mini P, Jurzak, Michael J, Samuels, Varman T, Shulman, Gerald I, Braun, Ursula, Leitges, Michael, Farese, Robert V
Publicado 2014

Akt-Dependent Phosphorylation of Hepatic FoxO1 Is Compartmentalized on a WD40/ProF Scaffold and Is Selectively Inhibited by aPKC in Early Phases of Diet-Induced Obesity

por Sajan, Mini P., Acevedo-Duncan, Mildred E., Standaert, Mary L., Ivey, Robert A., Lee, Mackenzie, Farese, Robert V.
Publicado 2014

Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells

por Jayson, Christina B. K., Arlt, Henning, Fischer, Alexander W., Lai, Zon Weng, Farese, Robert V., Walther, Tobias C.
Publicado 2018

Structure and catalytic mechanism of a human triglyceride synthesis enzyme

por Sui, Xuewu, Wang, Kun, Gluchowski, Nina L., Elliott, Shane D., Liao, Maofu, Walther, Tobias C., Farese, Robert V.
Publicado 2020

Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane

por Kim, Siyoung, Chung, Jeeyun, Arlt, Henning, Pak, Alexander J, Farese, Robert V, Walther, Tobias C, Voth, Gregory A
Publicado 2022

Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity

por Chitraju, Chandramohan, Fischer, Alexander W, Ambaw, Yohannes A, Wang, Kun, Yuan, Bo, Hui, Sheng, Walther, Tobias C, Farese, Robert V
Publicado 2023

In Vivo Metabolic Fingerprinting of Neutral Lipids with Hyperspectral Stimulated Raman Scattering Microscopy

por Fu, Dan, Yu, Yong, Folick, Andrew, Currie, Erin, Farese, Robert V., Tsai, Tsung-Huang, Xie, Xiaoliang Sunney, Wang, Meng C.
Publicado 2014

High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation

por Currie, Erin, Guo, Xiuling, Christiano, Romain, Chitraju, Chandramohan, Kory, Nora, Harrison, Kenneth, Haas, Joel, Walther, Tobias C., Farese, Robert V.
Publicado 2014

Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis

por Sui, Xuewu, Wang, Kun, Song, Kangkang, Xu, Chen, Song, Jiunn, Lee, Chia-Wei, Liao, Maofu, Farese, Robert V., Walther, Tobias C.
Publicado 2023