Clinical impact of splicing in neurodevelopmental disorders

por Sanders, Stephan J., Schwartz, Grace B., Farh, Kyle Kai-How
Publicado 2020

Predicting the clinical impact of human mutation with deep neural networks

por Sundaram, Laksshman, Gao, Hong, Padigepati, Samskruthi Reddy, McRae, Jeremy F., Li, Yanjun, Kosmicki, Jack A., Fritzilas, Nondas, Hakenberg, Jörg, Dutta, Anindita, Shon, John, Xu, Jinbo, Batzoglou, Serafim, Li, Xiaolin, Farh, Kyle Kai-How
Publicado 2018

Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation

por Jensen, Axel, Swift, Frances, de Vries, Dorien, Beck, Robin M D, Kuderna, Lukas F K, Knauf, Sascha, Chuma, Idrissa S, Keyyu, Julius D, Kitchener, Andrew C, Farh, Kyle, Rogers, Jeffrey, Marques-Bonet, Tomas, Detwiler, Kate M, Roos, Christian, Guschanski, Katerina
Publicado 2023

Rare penetrant mutations confer severe risk of common diseases

por Fiziev, Petko, McRae, Jeremy, Ulirsch, Jacob C., Dron, Jacqueline S., Hamp, Tobias, Yang, Yanshen, Wainschtein, Pierrick, Ni, Zijian, Schraiber, Joshua G., Gao, Hong, Cable, Dylan, Field, Yair, Aguet, Francois, Fasnacht, Marc, Metwally, Ahmed, Rogers, Jeffrey, Marques-Bonet, Tomas, Rehm, Heidi L., O’Donnell-Luria, Anne, Khera, Amit V., Kai-How Farh, Kyle
Publicado 2023

Partitioning heritability by functional annotation using genome-wide association summary statistics

por Finucane, Hilary K., Bulik-Sullivan, Brendan, Gusev, Alexander, Trynka, Gosia, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle, Ripke, Stephan, Day, Felix R., Consortium, ReproGen, Purcell, Shaun, Stahl, Eli, Lindstrom, Sara, Perry, John R. B., Okada, Yukinori, Raychaudhuri, Soumya, Daly, Mark, Patterson, Nick, Neale, Benjamin M., Price, Alkes L.
Publicado 2015

Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants

por Farh, Kyle Kai-How, Marson, Alexander, Zhu, Jiang, Kleinewietfeld, Markus, Housley, William J., Beik, Samantha, Shoresh, Noam, Whitton, Holly, Ryan, Russell J.H., Shishkin, Alexander A., Hatan, Meital, Carrasco-Alfonso, Marlene J., Mayer, Dita, Luckey, C. John, Patsopoulos, Nikolaos A., De Jager, Philip L., Kuchroo, Vijay K., Epstein, Charles B, Daly, Mark J., Hafler, David A., Bernstein, Bradley E.
Publicado 2014

Variation in predicted COVID-19 risk among lemurs and lorises

por Melin, Amanda D., Orkin, Joseph D., Janiak, Mareike C., Valenzuela, Alejandro, Kuderna, Lukas, Marrone, Frank, Ramangason, Hasinala, Horvath, Julie E., Roos, Christian, Kitchener, Andrew C., Khor, Chiea Chuen, Lim, Weng Khong, Lee, Jessica G. H., Tan, Patrick, Umapathy, Govindhaswamy, Raveendran, Muthuswamy, Harris, R. Alan, Gut, Ivo, Gut, Marta, Lizano, Esther, Nadler, Tilo, Zinner, Dietmar, Johnson, Steig E., Jarvis, Erich D., Fedrigo, Olivier, Wu, Dongdong, Zhang, Guojie, Farh, Kyle Kai-How, Rogers, Jeffrey, Marques-Bonet, Tomas, Navarro, Arcadi, Juan, David, Arora, Paramjit S., Higham, James P.
Publicado 2021

Fine-mapping inflammatory bowel disease loci to single variant resolution

por Huang, Hailiang, Fang, Ming, Jostins, Luke, Mirkov, Maša Umićević, Boucher, Gabrielle, Anderson, Carl A, Andersen, Vibeke, Cleynen, Isabelle, Cortes, Adrian, Crins, François, D'Amato, Mauro, Deffontaine, Valérie, Dimitrieva, Julia, Docampo, Elisa, Elansary, Mahmoud, Farh, Kyle Kai-How, Franke, Andre, Gori, Ann-Stephan, Goyette, Philippe, Halfvarson, Jonas, Haritunians, Talin, Knight, Jo, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mariman, Rob, Meuwissen, Theo, Mni, Myriam, Momozawa, Yukihide, Parkes, Miles, Spain, Sarah L, Théâtre, Emilie, Trynka, Gosia, Satsangi, Jack, van Sommeren, Suzanne, Vermeire, Severine, Xavier, Ramnik J, Weersma, Rinse K, Duerr, Richard H, Mathew, Christopher G, Rioux, John D, McGovern, Dermot PB, Cho, Judy H, Georges, Michel, Daly, Mark J, Barrett, Jeffrey C
Publicado 2017

DNA methylation landscapes in advanced prostate cancer

por Zhao, Shuang G., Chen, William S., Li, Haolong, Foye, Adam, Zhang, Meng, Sjöström, Martin, Aggarwal, Rahul, Playdle, Denise, Liao, Arnold, Alumkal, Joshi J., Das, Rajdeep, Chou, Jonathan, Hua, Junjie T., Barnard, Travis J., Bailey, Adina M., Chow, Eric, Perry, Marc, Dang, Ha X., Yang, Rendong, Moussavi-Baygi, Ruhollah, Zhang, Li, Alshalalfa, Mohammed, Chang, S. Laura, Houlahan, Kathleen E., Shiah, Yu-Jia, Beer, Tomasz M., Thomas, George, Chi, Kim N., Gleave, Martin, Zoubeidi, Amina, Reiter, Robert E., Rettig, Matthew B., Witte, Owen, Kim, M. Yvonne, Fong, Lawrence, Spratt, Daniel E., Morgan, Todd M, Bose, Rohit, Huang, Franklin W., Li, Hui, Chesner, Lisa, Shenoy, Tanushree, Goodarzi, Hani, Asangani, Irfan A., Sandhu, Shahneen, Lang, Joshua M., Mahajan, Nupam, Lara, Primo N., Evans, Christopher P., Febbo, Phillip, Batzoglou, Serafim, Knudsen, Karen E., He, Housheng H., Huang, Jiaoti, Zwart, Wilbert, Costello, Joseph F., Luo, Jianhua, Tomlins, Scott A., Wyatt, Alexander W., Dehm, Scott M., Ashworth, Alan, Gilbert, Luke A., Boutros, Paul C., Farh, Kyle, Chinnaiyan, Arul M., Maher, Christopher A., Small, Eric J., Quigley, David A., Feng, Felix Y.
Publicado 2020

Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

por Parikh, Victoria N., Ioannidis, Alexander G., Jimenez-Morales, David, Gorzynski, John E., De Jong, Hannah N., Liu, Xiran, Roque, Jonasel, Cepeda-Espinoza, Victoria P., Osoegawa, Kazutoyo, Hughes, Chris, Sutton, Shirley C., Youlton, Nathan, Joshi, Ruchi, Amar, David, Tanigawa, Yosuke, Russo, Douglas, Wong, Justin, Lauzon, Jessie T., Edelson, Jacob, Mas Montserrat, Daniel, Kwon, Yongchan, Rubinacci, Simone, Delaneau, Olivier, Cappello, Lorenzo, Kim, Jaehee, Shoura, Massa J., Raja, Archana N., Watson, Nathaniel, Hammond, Nathan, Spiteri, Elizabeth, Mallempati, Kalyan C., Montero-Martín, Gonzalo, Christle, Jeffrey, Kim, Jennifer, Kirillova, Anna, Seo, Kinya, Huang, Yong, Zhao, Chunli, Moreno-Grau, Sonia, Hershman, Steven G., Dalton, Karen P., Zhen, Jimmy, Kamm, Jack, Bhatt, Karan D., Isakova, Alina, Morri, Maurizio, Ranganath, Thanmayi, Blish, Catherine A., Rogers, Angela J., Nadeau, Kari, Yang, Samuel, Blomkalns, Andra, O’Hara, Ruth, Neff, Norma F., DeBoever, Christopher, Szalma, Sándor, Wheeler, Matthew T., Gates, Christian M., Farh, Kyle, Schroth, Gary P., Febbo, Phil, deSouza, Francis, Cornejo, Omar E., Fernandez-Vina, Marcelo, Kistler, Amy, Palacios, Julia A., Pinsky, Benjamin A., Bustamante, Carlos D., Rivas, Manuel A., Ashley, Euan A.
Publicado 2022

The landscape of tolerated genetic variation in humans and primates

por Gao, Hong, Hamp, Tobias, Ede, Jeffrey, Schraiber, Joshua G., McRae, Jeremy, Singer-Berk, Moriel, Yang, Yanshen, Dietrich, Anastasia, Fiziev, Petko, Kuderna, Lukas, Sundaram, Laksshman, Wu, Yibing, Adhikari, Aashish, Field, Yair, Chen, Chen, Batzoglou, Serafim, Aguet, Francois, Lemire, Gabrielle, Reimers, Rebecca, Balick, Daniel, Janiak, Mareike C., Kuhlwilm, Martin, Orkin, Joseph D., Manu, Shivakumara, Valenzuela, Alejandro, Bergman, Juraj, Rouselle, Marjolaine, Silva, Felipe Ennes, Agueda, Lidia, Blanc, Julie, Gut, Marta, de Vries, Dorien, Goodhead, Ian, Harris, R. Alan, Raveendran, Muthuswamy, Jensen, Axel, Chuma, Idriss S., Horvath, Julie, Hvilsom, Christina, Juan, David, Frandsen, Peter, de Melo, Fabiano R., Bertuol, Fabricio, Byrne, Hazel, Sampaio, Iracilda, Farias, Izeni, do Amaral, João Valsecchi, Messias, Mariluce, da Silva, Maria N. F., Trivedi, Mihir, Rossi, Rogerio, Hrbek, Tomas, Andriaholinirina, Nicole, Rabarivola, Clément J., Zaramody, Alphonse, Jolly, Clifford J., Phillips-Conroy, Jane, Wilkerson, Gregory, Abee, Christian, Simmons, Joe H., Fernandez-Duque, Eduardo, Kanthaswamy, Sree, Shiferaw, Fekadu, Wu, Dongdong, Zhou, Long, Shao, Yong, Zhang, Guojie, Keyyu, Julius D., Knauf, Sascha, Le, Minh D., Lizano, Esther, Merker, Stefan, Navarro, Arcadi, Batallion, Thomas, Nadler, Tilo, Khor, Chiea Chuen, Lee, Jessica, Tan, Patrick, Lim, Weng Khong, Kitchener, Andrew C., Zinner, Dietmar, Gut, Ivo, Melin, Amanda, Guschanski, Katerina, Schierup, Mikkel Heide, Beck, Robin M. D., Umapathy, Govindhaswamy, Roos, Christian, Boubli, Jean P., Lek, Monkol, Sunyaev, Shamil, O’Donnell, Anne, Rehm, Heidi, Xu, Jinbo, Rogers, Jeffrey, Marques-Bonet, Tomas, Kai-How Farh, Kyle
Publicado 2023