Role of UBE2C in Brain Cancer Invasion and Dissemination

por Domentean, Stefani, Paisana, Eunice, Cascão, Rita, Faria, Claudia C.
Publicado 2023

Cerebellar cystic glioblastomas: An uncommon presentation of a rare disease and clinical review

por Lavrador, José Pedro, Reis, José Hipólito, Belo, Diogo, Acharya, Shami, Faria, Cláudia C., Pimentel, José, Carvalho, Manuel Herculano
Publicado 2018

Abrogating Metastatic Properties of Triple-Negative Breast Cancer Cells by EGFR and PI3K Dual Inhibitors

por Garcia, Ana Rita, Mendes, Avilson, Custódia, Carlos, Faria, Cláudia C., Barata, João T., Malhó, Rui, Figueira, Inês, Brito, Maria Alexandra
Publicado 2023

Imaging mass spectrometry identifies prognostic ganglioside species in rodent intracranial transplants of glioma and medulloblastoma

por Ermini, Leonardo, Morganti, Elena, Post, Alexander, Yeganeh, Behzad, Caniggia, Isabella, Leadley, Michael, Faria, Claudia C., Rutka, James T., Post, Martin
Publicado 2017

Highlighted Advances in Therapies for Difficult-To-Treat Brain Tumours Such as Glioblastoma

por Cruz, Nuno, Herculano-Carvalho, Manuel, Roque, Diogo, Faria, Cláudia C., Cascão, Rita, Ferreira, Hugo Alexandre, Reis, Catarina Pinto, Matela, Nuno
Publicado 2023

Nanoparticle-Based Treatment in Glioblastoma

por Roque, Diogo, Cruz, Nuno, Ferreira, Hugo Alexandre, Reis, Catarina Pinto, Matela, Nuno, Herculano-Carvalho, Manuel, Cascão, Rita, Faria, Claudia C.
Publicado 2023

Medulloblastoma Development in a Patient with a Constitutional Balanced t(5;22)(q35.1;q11.2) Involving the NF2 Gene

por Nunes, Sofia, Faria, Claudia C., Pimentel, José, Roque, Rafael Fidalgo, Alaiz, Helena, Salazar, Isabel, Pereira, Teresa, Ferreira, Filipa, Roque, Lúcia
Publicado 2023

Patient-derived models of brain metastases recapitulate human disseminated disease

por Faria, Claudia C., Cascão, Rita, Custódia, Carlos, Paisana, Eunice, Carvalho, Tânia, Pereira, Pedro, Roque, Rafael, Pimentel, José, Miguéns, José, Cortes-Ciriano, Isidro, Barata, João T.
Publicado 2022

A functional genomics approach to identify pathways of drug resistance in medulloblastoma

por Bertrand, Kelsey C., Faria, Claudia C., Skowron, Patryk, Luck, Amanda, Garzia, Livia, Wu, Xiaochong, Agnihotri, Sameer, Smith, Christian A., Taylor, Michael D., Mack, Stephen C., Rutka, James T.
Publicado 2018

BSCI-04 TARGETING THE PI3K-MTOR PATHWAY TO TREAT UBE2C-DRIVEN BRAIN METASTASES

por Paisana, Eunice, Cascão, Rita, Custódia, Carlos, Qin, Nan, Picard, Daniel, Pauck, David, Carvalho, Tânia, Ruivo, Pedro, Roque, Rafael, Pimentel, José, Remke, Marc, Barata, João T, Faria, Cláudia C
Publicado 2022

LMD-12. Ubiquitin Conjugating Enzymes promote leptomeningeal dissemination and decrease survival in patients with brain metastatic disease

por Paisana, Eunice, Cascão, Rita, Custódia, Carlos, Qin, Nan, Picard, Daniel, Pauck, David, Carvalho, Tânia, Ruivo, Pedro, Pereira, Pedro, Roque, Rafael, Pimentel, José, Miguéns, José, Remke, Marc, Barata, João T, Faria, Claudia C
Publicado 2021

The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma

por Qin, Nan, Paisana, Eunice, Picard, Daniel, Leprivier, Gabriel, Langini, Maike, Custódia, Carlos, Cascão, Rita, Conrad, Catleen, Peitzsch, Mirko, Stefanski, Anja, Stühler, Kai, Fischer, Ute, Faria, Claudia C., Dietrich, Sascha, Reifenberger, Guido, Remke, Marc
Publicado 2023

UBE2C promotes leptomeningeal dissemination and is a therapeutic target in brain metastatic disease

por Paisana, Eunice, Cascão, Rita, Custódia, Carlos, Qin, Nan, Picard, Daniel, Pauck, David, Carvalho, Tânia, Ruivo, Pedro, Barreto, Clara, Doutel, Delfim, Cabeçadas, José, Roque, Rafael, Pimentel, José, Miguéns, José, Remke, Marc, Barata, João T, Faria, Claudia C
Publicado 2023

Cadherin‐3 is a novel oncogenic biomarker with prognostic value in glioblastoma

por Martins, Eduarda P., Gonçalves, Céline S., Pojo, Marta, Carvalho, Rita, Ribeiro, Ana S., Miranda‐Gonçalves, Vera, Taipa, Ricardo, Pardal, Fernando, Pinto, Afonso A., Custódia, Carlos, Faria, Cláudia C., Baltazar, Fátima, Sousa, Nuno, Paredes, Joana, Costa, Bruno M.
Publicado 2022

Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma

por Faria, Claudia C., Agnihotri, Sameer, Mack, Stephen C., Golbourn, Brian J., Diaz, Roberto J., Olsen, Samantha, Bryant, Melissa, Bebenek, Matthew, Wang, Xin, Bertrand, Kelsey C., Kushida, Michelle, Head, Renee, Clark, Ian, Dirks, Peter, Smith, Christian A., Taylor, Michael D., Rutka, James T.
Publicado 2015

WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma

por Gonçalves, Céline S., Vieira de Castro, Joana, Pojo, Marta, Martins, Eduarda P., Queirós, Sandro, Chautard, Emmanuel, Taipa, Ricardo, Pires, Manuel Melo, Pinto, Afonso A., Pardal, Fernando, Custódia, Carlos, Faria, Cláudia C., Clara, Carlos, Reis, Rui M., Sousa, Nuno, Costa, Bruno M.
Publicado 2018

Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma

por Picard, Daniel, Felsberg, Jörg, Langini, Maike, Stachura, Paweł, Qin, Nan, Macas, Jadranka, Reiss, Yvonne, Bartl, Jasmin, Selt, Florian, Sigaud, Romain, Meyer, Frauke-D., Stefanski, Anja, Stühler, Kai, Roque, Lucia, Roque, Rafael, Pandyra, Aleksandra A., Brozou, Triantafyllia, Knobbe-Thomsen, Christiane, Plate, Karl H., Roesch, Alexander, Milde, Till, Reifenberger, Guido, Leprivier, Gabriel, Faria, Claudia C., Remke, Marc
Publicado 2023

Medulloblastoma has a global impact on health related quality of life: Findings from an international cohort

por de Medeiros, Cynthia B., Moxon‐Emre, Iska, Scantlebury, Nadia, Malkin, David, Ramaswamy, Vijay, Decker, Alexandra, Law, Nicole, Kumabe, Toshihiro, Leonard, Jeffrey, Rubin, Josh, Jung, Shin, Kim, Seung‐Ki, Gupta, Nalin, Weiss, William, Faria, Claudia C., Vibhakar, Rajeev, Lafay‐Cousin, Lucie, Chan, Jennifer, Kros, Johan M., Janzen, Laura, Taylor, Michael D., Bouffet, Eric, Mabbott, Donald J.
Publicado 2019

Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors

por Blümel, Lena, Qin, Nan, Berlandi, Johannes, Paisana, Eunice, Cascão, Rita, Custódia, Carlos, Pauck, David, Picard, Daniel, Langini, Maike, Stühler, Kai, Meyer, Frauke-Dorothee, Göbbels, Sarah, Malzkorn, Bastian, Liebau, Max C., Barata, João T., Jeibmann, Astrid, Kerl, Kornelius, Erkek, Serap, Kool, Marcel, Pfister, Stefan M., Johann, Pascal D., Frühwald, Michael C., Borkhardt, Arndt, Reifenberger, Guido, Faria, Claudia C., Fischer, Ute, Hasselblatt, Martin, Bartl, Jasmin, Remke, Marc
Publicado 2022

Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression

por Conde, João, Pumroy, Ruth A., Baker, Charlotte, Rodrigues, Tiago, Guerreiro, Ana, Sousa, Bárbara B., Marques, Marta C., de Almeida, Bernardo P., Lee, Sohyon, Leites, Elvira P., Picard, Daniel, Samanta, Amrita, Vaz, Sandra H., Sieglitz, Florian, Langini, Maike, Remke, Marc, Roque, Rafael, Weiss, Tobias, Weller, Michael, Liu, Yuhang, Han, Seungil, Corzana, Francisco, Morais, Vanessa A., Faria, Cláudia C., Carvalho, Tânia, Filippakopoulos, Panagis, Snijder, Berend, Barbosa-Morais, Nuno L., Moiseenkova-Bell, Vera Y., Bernardes, Gonçalo J. L.
Publicado 2021