Very low-depth sequencing in a founder population identifies a cardioprotective APOC3 signal missed by genome-wide imputation

por Gilly, Arthur, Ritchie, Graham Rs, Southam, Lorraine, Farmaki, Aliki-Eleni, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Publicado 2016

HbA1c and brain health across the entire glycaemic spectrum

por Garfield, Victoria, Farmaki, Aliki‐Eleni, Eastwood, Sophie V., Mathur, Rohini, Rentsch, Christopher T., Bhaskaran, Krishnan, Smeeth, Liam, Chaturvedi, Nish
Publicado 2021

Risk of 16 cancers across the full glycemic spectrum: a population-based cohort study using the UK Biobank

por Rentsch, Christopher T, Farmer, Ruth E, Eastwood, Sophie V, Mathur, Rohini, Garfield, Victoria, Farmaki, Aliki-Eleni, Bhaskaran, Krishnan, Chaturvedi, Nish, Smeeth, Liam
Publicado 2020

Adiposity and grip strength: a Mendelian randomisation study in UK Biobank

por Pinto Pereira, Snehal M., Garfield, Victoria, Farmaki, Aliki-Eleni, Tomlinson, David J., Norris, Thomas, Fatemifar, Ghazaleh, Denaxas, Spiros, Finan, Chris, Cooper, Rachel
Publicado 2022

The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis

por Miller, Suzanne, Coveney, Clare, Johnson, Janice, Farmaki, Aliki-Eleni, Gupta, Nishant, Tobin, Martin D., Wain, Louise V., McCormack, Francis X., Boocock, David J., Johnson, Simon R.
Publicado 2018

Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits

por Southam, Lorraine, Gilly, Arthur, Süveges, Dániel, Farmaki, Aliki-Eleni, Schwartzentruber, Jeremy, Tachmazidou, Ioanna, Matchan, Angela, Rayner, Nigel W., Tsafantakis, Emmanouil, Karaleftheri, Maria, Xue, Yali, Dedoussis, George, Zeggini, Eleftheria
Publicado 2017

A Dietary Pattern with High Sugar Content Is Associated with Cardiometabolic Risk Factors in the Pomak Population

por Farmaki, Aliki-Eleni, Rayner, Nigel W, Kafyra, Maria, Matchan, Angela, Ntaoutidou, Kyriaki, Feritoglou, Pournar, Athanasiadis, Antonis, Gilly, Arthur, Mamakou, Vasiliki, Zengini, Eleni, Karaleftheri, Maria, Zeggini, Eleftheria, Dedoussis, George
Publicado 2019

Type 2 diabetes risks and determinants in second-generation migrants and mixed ethnicity people of South Asian and African Caribbean descent in the UK

por Farmaki, Aliki-Eleni, Garfield, Victoria, Eastwood, Sophie V., Farmer, Ruth E., Mathur, Rohini, Giannakopoulou, Olga, Patalay, Praveetha, Kuchenbaecker, Karoline, Sattar, Naveed, Hughes, Alun, Bhaskaran, Krishnan, Smeeth, Liam, Chaturvedi, Nish
Publicado 2021

Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations

por Kuchenbaecker, Karoline, Gilly, Arthur, Suveges, Daniel, Southam, Lorraine, Giannakopoulou, Olga, Kilian, Britt, Tsafantakis, Emmanouil, Karaleftheri, Maria, Farmaki, Aliki-Eleni, Gurdasani, Deepti, Kundu, Kousik, Sandhu, Manjinder S., Danesh, John, Butterworth, Adam, Barroso, Inês, Dedoussis, George, Zeggini, Eleftheria
Publicado 2022

Very low-depth whole-genome sequencing in complex trait association studies

por Gilly, Arthur, Southam, Lorraine, Suveges, Daniel, Kuchenbaecker, Karoline, Moore, Rachel, Melloni, Giorgio E M, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Ritchie, Graham, Schwartzentruber, Jeremy, Danecek, Petr, Kilian, Britt, Pollard, Martin O, Ge, Xiangyu, Tsafantakis, Emmanouil, Dedoussis, George, Zeggini, Eleftheria
Publicado 2019

Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank

por Fawcett, Katherine A., Song, Kijoung, Qian, Guoqing, Farmaki, Aliki-Eleni, Packer, Richard, John, Catherine, Shrine, Nick, Granell, Raquel, Ring, Sue, Timpson, Nicholas J., Yerges-Armstrong, Laura M., Eastell, Richard, Wain, Louise V., Scott, Robert A., Tobin, Martin D., Hall, Ian P.
Publicado 2021

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

por Gilly, Arthur, Suveges, Daniel, Kuchenbaecker, Karoline, Pollard, Martin, Southam, Lorraine, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Bjornland, Thea, Waples, Ryan, Appel, Emil V. R., Casalone, Elisabetta, Melloni, Giorgio, Kilian, Britt, Rayner, Nigel W., Ntalla, Ioanna, Kundu, Kousik, Walter, Klaudia, Danesh, John, Butterworth, Adam, Barroso, Inês, Tsafantakis, Emmanouil, Dedoussis, George, Moltke, Ida, Zeggini, Eleftheria
Publicado 2018

Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

por Gilly, Arthur, Suveges, Daniel, Kuchenbaecker, Karoline, Pollard, Martin, Southam, Lorraine, Hatzikotoulas, Konstantinos, Farmaki, Aliki-Eleni, Bjornland, Thea, Waples, Ryan, Appel, Emil V. R., Casalone, Elisabetta, Melloni, Giorgio, Kilian, Britt, Rayner, Nigel W., Ntalla, Ioanna, Kundu, Kousik, Walter, Klaudia, Danesh, John, Butterworth, Adam, Barroso, Inês, Tsafantakis, Emmanouil, Dedoussis, George, Moltke, Ida, Zeggini, Eleftheria
Publicado 2018

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

por Tachmazidou, Ioanna, Dedoussis, George, Southam, Lorraine, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Xifara, Dionysia K., Matchan, Angela, Hatzikotoulas, Konstantinos, Rayner, Nigel W., Chen, Yuan, Pollin, Toni I., O’Connell, Jeffrey R., Yerges-Armstrong, Laura M., Kiagiadaki, Chrysoula, Panoutsopoulou, Kalliope, Schwartzentruber, Jeremy, Moutsianas, Loukas, Tsafantakis, Emmanouil, Tyler-Smith, Chris, McVean, Gil, Xue, Yali, Zeggini, Eleftheria
Publicado 2013

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

por Panoutsopoulou, Kalliope, Hatzikotoulas, Konstantinos, Xifara, Dionysia Kiara, Colonna, Vincenza, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Southam, Lorraine, Gilly, Arthur, Tachmazidou, Ioanna, Fatumo, Segun, Matchan, Angela, Rayner, Nigel W., Ntalla, Ioanna, Mezzavilla, Massimo, Chen, Yuan, Kiagiadaki, Chrysoula, Zengini, Eleni, Mamakou, Vasiliki, Athanasiadis, Antonis, Giannakopoulou, Margarita, Kariakli, Vassiliki-Eirini, Nsubuga, Rebecca N., Karabarinde, Alex, Sandhu, Manjinder, McVean, Gil, Tyler-Smith, Chris, Tsafantakis, Emmanouil, Karaleftheri, Maria, Xue, Yali, Dedoussis, George, Zeggini, Eleftheria
Publicado 2014

Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

por John, Catherine, Reeve, Nicola F, Free, Robert C, Williams, Alexander T, Ntalla, Ioanna, Farmaki, Aliki-Eleni, Bethea, Jane, Barton, Linda M, Shrine, Nick, Batini, Chiara, Packer, Richard, Terry, Sarah, Hargadon, Beverley, Wang, Qingning, Melbourne, Carl A, Adams, Emma L, Bee, Catherine E, Harrington, Kyla, Miola, José, Brunskill, Nigel J, Brightling, Christopher E, Barwell, Julian, Wallace, Susan E, Hsu, Ron, Shepherd, David J, Hollox, Edward J, Wain, Louise V, Tobin, Martin D
Publicado 2019

Corrigendum to: Cohort profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

por John, Catherine, Reeve, Nicola F, Free, Robert C, Williams, Alexander T, Ntalla, Ioanna, Farmaki, Aliki-Eleni, Bethea, Jane, Barton, Linda M, Shrine, Nick, Batini, Chiara, Packer, Richard, Terry, Sarah, Hargadon, Beverley, Wang, Qingning, Melbourne, Carl A, Adams, Emma L, Bee, Catherine E, Harrington, Kyla, Miola, José, Brunskill, Nigel J, Brightling, Christopher E, Barwell, Julian, Wallace, Susan E, Hsu, Ron, Shepherd, David J, Hollox, Edward J, Wain, Louise V, Tobin, Martin D
Publicado 2019

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

por Timpson, Nicholas J., Walter, Klaudia, Min, Josine L., Tachmazidou, Ioanna, Malerba, Giovanni, Shin, So-Youn, Chen, Lu, Futema, Marta, Southam, Lorraine, Iotchkova, Valentina, Cocca, Massimiliano, Huang, Jie, Memari, Yasin, McCarthy, Shane, Danecek, Petr, Muddyman, Dawn, Mangino, Massimo, Menni, Cristina, Perry, John R. B., Ring, Susan M., Gaye, Amadou, Dedoussis, George, Farmaki, Aliki-Eleni, Burton, Paul, Talmud, Philippa J., Gambaro, Giovanni, Spector, Tim D., Smith, George Davey, Durbin, Richard, Richards, J Brent, Humphries, Steve E., Zeggini, Eleftheria, Soranzo, Nicole
Publicado 2014

Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

por Timpson, Nicholas J., Walter, Klaudia, Min, Josine L., Tachmazidou, Ioanna, Malerba, Giovanni, Shin, So-Youn, Chen, Lu, Futema, Marta, Southam, Lorraine, Iotchkova, Valentina, Cocca, Massimiliano, Huang, Jie, Memari, Yasin, McCarthy, Shane, Danecek, Petr, Muddyman, Dawn, Mangino, Massimo, Menni, Cristina, Perry, John R. B., Ring, Susan M., Gaye, Amadou, Dedoussis, George, Farmaki, Aliki-Eleni, Burton, Paul, Talmud, Philippa J., Gambaro, Giovanni, Spector, Tim D., Smith, George Davey, Durbin, Richard, Richards, J. Brent, Humphries, Steve E., Zeggini, Eleftheria, Soranzo, Nicole
Publicado 2015

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

por Tachmazidou, Ioanna, Süveges, Dániel, Min, Josine L., Ritchie, Graham R.S., Steinberg, Julia, Walter, Klaudia, Iotchkova, Valentina, Schwartzentruber, Jeremy, Huang, Jie, Memari, Yasin, McCarthy, Shane, Crawford, Andrew A., Bombieri, Cristina, Cocca, Massimiliano, Farmaki, Aliki-Eleni, Gaunt, Tom R., Jousilahti, Pekka, Kooijman, Marjolein N., Lehne, Benjamin, Malerba, Giovanni, Männistö, Satu, Matchan, Angela, Medina-Gomez, Carolina, Metrustry, Sarah J., Nag, Abhishek, Ntalla, Ioanna, Paternoster, Lavinia, Rayner, Nigel W., Sala, Cinzia, Scott, William R., Shihab, Hashem A., Southam, Lorraine, St Pourcain, Beate, Traglia, Michela, Trajanoska, Katerina, Zaza, Gialuigi, Zhang, Weihua, Artigas, María S., Bansal, Narinder, Benn, Marianne, Chen, Zhongsheng, Danecek, Petr, Lin, Wei-Yu, Locke, Adam, Luan, Jian’an, Manning, Alisa K., Mulas, Antonella, Sidore, Carlo, Tybjaerg-Hansen, Anne, Varbo, Anette, Zoledziewska, Magdalena, Finan, Chris, Hatzikotoulas, Konstantinos, Hendricks, Audrey E., Kemp, John P., Moayyeri, Alireza, Panoutsopoulou, Kalliope, Szpak, Michal, Wilson, Scott G., Boehnke, Michael, Cucca, Francesco, Di Angelantonio, Emanuele, Langenberg, Claudia, Lindgren, Cecilia, McCarthy, Mark I., Morris, Andrew P., Nordestgaard, Børge G., Scott, Robert A., Tobin, Martin D., Wareham, Nicholas J., Burton, Paul, Chambers, John C., Smith, George Davey, Dedoussis, George, Felix, Janine F., Franco, Oscar H., Gambaro, Giovanni, Gasparini, Paolo, Hammond, Christopher J., Hofman, Albert, Jaddoe, Vincent W.V., Kleber, Marcus, Kooner, Jaspal S., Perola, Markus, Relton, Caroline, Ring, Susan M., Rivadeneira, Fernando, Salomaa, Veikko, Spector, Timothy D., Stegle, Oliver, Toniolo, Daniela, Uitterlinden, André G., Barroso, Inês, Greenwood, Celia M.T., Perry, John R.B., Walker, Brian R., Butterworth, Adam S., Xue, Yali, Durbin, Richard, Small, Kerrin S., Soranzo, Nicole, Timpson, Nicholas J., Zeggini, Eleftheria
Publicado 2017