Skeletal Senescence with Aging and Type 2 Diabetes

por Farr, Joshua Nicholas
Publicado 2023

Cellular senescence and the skeleton: pathophysiology and therapeutic implications

por Khosla, Sundeep, Farr, Joshua N., Monroe, David G.
Publicado 2022

Periodontal Disease and Senescent Cells: New Players for an Old Oral Health Problem?

por Aquino-Martinez, Ruben, Khosla, Sundeep, Farr, Joshua N., Monroe, David G.
Publicado 2020

MicroRNA‐19a‐3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence

por Kaur, Japneet, Saul, Dominik, Doolittle, Madison L., Farr, Joshua N., Khosla, Sundeep, Monroe, David G.
Publicado 2023

Predictors of teriparatide treatment failure in patients with low bone mass

por Elraiyah, Tarig, Ahmed, Adil H., Wang, Zhen, Farr, Joshua N., Murad, Mohammad H., Drake, Matthew T.
Publicado 2015

Beta-Catenin Haplo Insufficient Male Mice Do Not Lose Bone in Response to Hindlimb Unloading

por Maurel, Delphine B., Duan, Peipei, Farr, Joshua, Cheng, An-Lin, Johnson, Mark L., Bonewald, Lynda F.
Publicado 2016

Lower Trabecular Volumetric BMD at Metaphyseal Regions of Weight-Bearing Bones is Associated With Prior Fracture in Young Girls

por Farr, Joshua N, Tomás, Rita, Chen, Zhao, Lisse, Jeffrey R, Lohman, Timothy G, Going, Scott B
Publicado 2011

Identification of a suitable endogenous control miRNA in bone aging and senescence

por Kaur, Japneet, Saul, Dominik, Doolittle, Madison L., Rowsey, Jennifer L., Vos, Stephanie J., Farr, Joshua N., Khosla, Sundeep, Monroe, David G.
Publicado 2022

Modulation of fracture healing by the transient accumulation of senescent cells

por Saul, Dominik, Monroe, David G, Rowsey, Jennifer L, Kosinsky, Robyn Laura, Vos, Stephanie J, Doolittle, Madison L, Farr, Joshua N, Khosla, Sundeep
Publicado 2021

Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton

por Doolittle, Madison L., Saul, Dominik, Kaur, Japneet, Rowsey, Jennifer L., Vos, Stephanie J., Pavelko, Kevin D., Farr, Joshua N., Monroe, David G., Khosla, Sundeep
Publicado 2023

Myostatin as a mediator of sarcopenia versus homeostatic regulator of muscle mass: insights using a new mass spectrometry-based assay

por Bergen, H. Robert, Farr, Joshua N., Vanderboom, Patrick M., Atkinson, Elizabeth J., White, Thomas A., Singh, Ravinder J., Khosla, Sundeep, LeBrasseur, Nathan K.
Publicado 2015

SUN-LB68 Advanced Glycation Endproducts Are Associated With Worse Bone Material Strength in Older Adults With and Without Type 2 Diabetes

por Samakkarnthai, Parinya, Sfeir, Jad G, Atkinson, Elizabeth J, Achenbach, Sara J, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Farr, Joshua N, Khosla, Sundeep
Publicado 2020

Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton

por Doolittle, Madison L., Saul, Dominik, Kaur, Japneet, Rowsey, Jennifer L., Vos, Stephanie J., Pavelko, Kevin D., Farr, Joshua N., Monroe, David G., Khosla, Sundeep
Publicado 2023

Modest Effects of Osteoclast‐Specific ERα Deletion after Skeletal Maturity

por Doolittle, Madison L., Eckhardt, Brittany A., Vos, Stephanie J., Grain, Sarah, Rowsey, Jennifer L., Ruan, Ming, Saul, Dominik, Farr, Joshua N., Weivoda, Megan M., Khosla, Sundeep, Monroe, David G.
Publicado 2023

SUN-381 Cortical Porosity Is Associated with Peripheral Small Vessel Disease in Adult Patients with Type 2 Diabetes

por Samakkarnthai, Parinya, Sfeir, Jad G, Wennberg, Paul W, Dyck, Peter J, Achenbach, Sara J, Atkinson, Elizabeth J, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Farr, Joshua N, Khosla, Sundeep
Publicado 2020

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

por Farr, Joshua N., Roforth, Matthew M., Fujita, Koji, Nicks, Kristy M., Cunningham, Julie M., Atkinson, Elizabeth J., Therneau, Terry M., McCready, Louise K., Peterson, James M., Drake, Matthew T., Monroe, David G., Khosla, Sundeep
Publicado 2015

Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study

por Rufus-Membere, Pamela, Holloway-Kew, Kara L., Diez-Perez, Adolfo, Appelman-Dijkstra, Natasha M., Bouxsein, Mary L., Eriksen, Erik F., Farr, Joshua N., Khosla, Sundeep, Kotowicz, Mark A., Nogues, Xavier, Rubin, Mishaela, Pasco, Julie A.
Publicado 2023

Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity

por Chandra, Abhishek, Lagnado, Anthony B., Farr, Joshua N., Doolittle, Madison, Tchkonia, Tamara, Kirkland, James L., LeBrasseur, Nathan K., Robbins, Paul D., Niedernhofer, Laura J., Ikeno, Yuji, Passos, João F., Monroe, David G., Pignolo, Robert J., Khosla, Sundeep
Publicado 2022

In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers

por Samakkarnthai, Parinya, Saul, Dominik, Zhang, Lei, Aversa, Zaira, Doolittle, Madison L., Sfeir, Jad G., Kaur, Japneet, Atkinson, Elizabeth J., Edwards, James R., Russell, Graham G., Pignolo, Robert J., Kirkland, James L., Tchkonia, Tamar, Niedernhofer, Laura J., Monroe, David G., Lebrasseur, Nathan K., Farr, Joshua N., Robbins, Paul D., Khosla, Sundeep
Publicado 2023

Targeting cellular senescence prevents age-related bone loss in mice

por Farr, Joshua N., Xu, Ming, Weivoda, Megan M., Monroe, David G., Fraser, Daniel G., Onken, Jennifer L., Negley, Brittany A., Sfeir, Jad G., Ogrodnik, Mikolaj B., Hachfeld, Christine M., LeBrasseur, Nathan K., Drake, Matthew T., Pignolo, Robert J., Pirtskhalava, Tamar, Tchkonia, Tamara, Oursler, Merry Jo, Kirkland, James L., Khosla, Sundeep
Publicado 2017