Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice

por Price, Tulin O., Farr, Susan A., Niehoff, Michael L., Ercal, Nuran, Morley, John E., Shah, Gul N.
Publicado 2015

Adenosine A(3) receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury

por Farr, Susan A., Cuzzocrea, Salvatore, Esposito, Emanuela, Campolo, Michela, Niehoff, Michael L., Doyle, Timothy M., Salvemini, Daniela
Publicado 2020

A Life without Hunger: The Ups (and Downs) to Modulating Melanocortin-3 Receptor Signaling

por Butler, Andrew A., Girardet, Clemence, Mavrikaki, Maria, Trevaskis, James L., Macarthur, Heather, Marks, Daniel L., Farr, Susan A.
Publicado 2017

Biochemical, biomarker, and behavioral characterization of the Grn(R493X) mouse model of frontotemporal dementia

por Smith, Denise M., Aggarwal, Geetika, Niehoff, Michael L., Jones, Spencer A., Banerjee, Subhashis, Farr, Susan A., Nguyen, Andrew D.
Publicado 2023

Aging, Plasminogen Activator Inhibitor 1, Brain Cell Senescence, and Alzheimer’s Disease

por Jiang, Chun-Sun, Rana, Tapasi, Jin, Lee-Way, Farr, Susan A, Morley, John E, Qin, Hongwei, Liu, Gang, Liu, Rui-Ming
Publicado 2023

Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn (R493X) mouse model of frontotemporal dementia

por Smith, Denise M., Niehoff, Michael L., Ling, Karen, Jafar-Nejad, Paymaan, Rigo, Frank, Farr, Susan A., Wilkinson, Miles F., Nguyen, Andrew D.
Publicado 2023

Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment

por Squillace, Silvia, Niehoff, Michael L., Doyle, Timothy M., Green, Michael, Esposito, Emanuela, Cuzzocrea, Salvatore, Arnatt, Christopher K., Spiegel, Sarah, Farr, Susan A., Salvemini, Daniela
Publicado 2022

The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer’s Disease

por Hansen, Henrik H., Fabricius, Katrine, Barkholt, Pernille, Niehoff, Michael L., Morley, John E., Jelsing, Jacob, Pyke, Charles, Knudsen, Lotte Bjerre, Farr, Susan A., Vrang, Niels
Publicado 2015

Targeting the A(3) adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice

por Singh, Anand Kumar, Mahalingam, Rajasekaran, Squillace, Silvia, Jacobson, Kenneth A., Tosh, Dilip K., Dharmaraj, Shruti, Farr, Susan A., Kavelaars, Annemieke, Salvemini, Daniela, Heijnen, Cobi J.
Publicado 2022

Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

por Roby, Deborah A., Ruiz, Fernanda, Kermath, Bailey A., Voorhees, Jaymie R., Niehoff, Michael, Zhang, Jinsong, Morley, John E., Musiek, Erik S., Farr, Susan A., Burris, Thomas P.
Publicado 2019

Multi-parametric MRI of Kidney Disease Progression for Autosomal Recessive Polycystic Kidney Disease (ARPKD): Mouse Model and Initial Patient Results

por MacAskill, Christina J., Erokwu, Bernadette O., Markley, Michael, Parsons, Ashlee, Farr, Susan, Zhang, Yifan, Tran, Uyen, Chen, Yong, Anderson, Christian E., Serai, Suraj, Hartung, Erum A., Wessely, Oliver, Ma, Dan, Dell, Katherine M., Flask, Chris A.
Publicado 2020

Neurovascular protection by adropin in experimental ischemic stroke through an endothelial nitric oxide synthase-dependent mechanism

por Yang, Changjun, Lavayen, Bianca P., Liu, Lei, Sanz, Brian D., DeMars, Kelly M., Larochelle, Jonathan, Pompilus, Marjory, Febo, Marcelo, Sun, Yu-Yo, Kuo, Yi-Min, Mohamadzadeh, Mansour, Farr, Susan A., Kuan, Chia-Yi, Butler, Andrew A., Candelario-Jalil, Eduardo
Publicado 2021

Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

por Banerjee, Subhashis, Ghoshal, Sarbani, Girardet, Clemence, DeMars, Kelly M., Yang, Changjun, Niehoff, Michael L., Nguyen, Andrew D., Jayanth, Prerana, Hoelscher, Brittany A., Xu, Fenglian, Banks, William A., Hansen, Kim M., Zhang, Jinsong, Candelario-Jalil, Eduardo, Farr, Susan A., Butler, Andrew A.
Publicado 2021

Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer’s disease

por Erickson, Michelle A., Logsdon, Aric F., Rhea, Elizabeth M., Hansen, Kim M., Holden, Sarah J, Banks, William A, Smith, Jessica L., German, Cody, Farr, Susan A., Morley, John E., Weaver, Riley R, Hirsch, Alec J., Kovac, Andrej, Kontsekova, Eva, Baumann, Kristen K., Omer, Mohamed A., Raber, Jacob
Publicado 2023

A DUAL MTOR/NAD+ ACTING GEROTHERAPY

por Li, Jinmei, Kumar, Sandeep, Miachin, Kirill, Bean, Nicholas L., Halawi, Ornella, Lee, Scott, Park, JiWoong, Pierre, Tanya H., Hor, Jin-Hui, Ng, Shi-Yan, Wallace, Kelvin J., Rindtorff, Niklas, Miller, Timothy M., Niehoff, Michael L., Farr, Susan A., Kletzien, Rolf F., Colca, Jerry, Tanis, Steven P., Chen, Yana, Griffett, Kristine, McCommis, Kyle S., Finck, Brian N., Peterson, Tim R.
Publicado 2023