Mutant Cu/Zn Superoxide Dismutase (A4V) Turnover Is Altered in Cells Containing Inclusions

por Farrawell, Natalie E., Yerbury, Justin J.
Publicado 2021

Ubiquitin homeostasis disruption, a common cause of proteostasis collapse in amyotrophic lateral sclerosis?

por Chisholm, Christen G., Lum, Jeremy S., Farrawell, Natalie E., Yerbury, Justin J.
Publicado 2022

Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies

por Wyatt, Amy R., Kumita, Janet R., Farrawell, Natalie E., Dobson, Christopher M., Wilson, Mark R.
Publicado 2015

Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells

por Pokrishevsky, Edward, McAlary, Luke, Farrawell, Natalie E., Zhao, Beibei, Sher, Mine, Yerbury, Justin J., Cashman, Neil R.
Publicado 2018

Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

por Farrawell, Natalie E., Lambert-Smith, Isabella A., Warraich, Sadaf T., Blair, Ian P., Saunders, Darren N., Hatters, Danny M., Yerbury, Justin J.
Publicado 2015

Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS

por Farrawell, Natalie E., McAlary, Luke, Lum, Jeremy S., Chisholm, Christen G., Warraich, Sadaf T., Blair, Ian P., Vine, Kara L., Saunders, Darren N., Yerbury, Justin J.
Publicado 2020

ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis

por Farrawell, Natalie E, Bax, Monique, McAlary, Luke, McKenna, Jessie, Maksour, Simon, Do-Ha, Dzung, Rayner, Stephanie L, Blair, Ian P, Chung, Roger S, Yerbury, Justin J, Ooi, Lezanne, Saunders, Darren N
Publicado 2023

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation

por Bax, Monique, McKenna, Jessie, Do-Ha, Dzung, Stevens, Claire H., Higginbottom, Sarah, Balez, Rachelle, Cabral-da-Silva, Mauricio e Castro, Farrawell, Natalie E., Engel, Martin, Poronnik, Philip, Yerbury, Justin J., Saunders, Darren N., Ooi, Lezanne
Publicado 2019

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1(G93A) mice with a C57BL/6 background

por Lum, Jeremy S., Brown, Mikayla L., Farrawell, Natalie E., McAlary, Luke, Ly, Diane, Chisholm, Christen G., Snow, Josh, Vine, Kara L., Karl, Tim, Kreilaus, Fabian, McInnes, Lachlan E., Nikseresht, Sara, Donnelly, Paul S., Crouch, Peter J., Yerbury, Justin J.
Publicado 2021