Genetics and genomics of Parkinson’s disease

por Lin, Michelle K, Farrer, Matthew J
Publicado 2014

Dynamic control of the dopamine transporter in neurotransmission and homeostasis

por Bu, Mengfei, Farrer, Matthew J., Khoshbouei, Habibeh
Publicado 2021

Experimental procedures for flow cytometry of wild-type mouse brain: a systematic review

por Sharp, Robert C., Guenther, Dylan T., Farrer, Matthew J.
Publicado 2023

Genetic association study of synphilin-1 in idiopathic Parkinson's disease

por Myhre, Ronny, Klungland, Helge, Farrer, Matthew J, Aasly, Jan O
Publicado 2008

PSEN1 p.Met233Val in a Complex Neurodegenerative Movement and Neuropsychiatric Disorder

por Appel-Cresswell, Silke, Guella, Ilaria, Lehman, Anna, Foti, Dean, Farrer, Matthew J.
Publicado 2018

Chronic and Acute Manipulation of Cortical Glutamate Transmission Induces Structural and Synaptic Changes in Co-cultured Striatal Neurons

por Kuhlmann, Naila, Wagner Valladolid, Miriam, Quesada-Ramírez, Lucía, Farrer, Matthew J., Milnerwood, Austen J.
Publicado 2021

A Case of Parkinson's Disease with No Lewy Body Pathology due to a Homozygous Exon Deletion in Parkin

por Johansen, Krisztina Kunszt, Torp, Sverre Helge, Farrer, Matthew J., Gustavsson, Emil K., Aasly, Jan O.
Publicado 2018

A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism

por Book, Adam, Guella, Ilaria, Candido, Tara, Brice, Alexis, Hattori, Nobutaka, Jeon, Beomseok, Farrer, Matthew J.
Publicado 2018

Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia

por Maekawa, Tatsunori, Sasaoka, Toshikuni, Azuma, Sadahiro, Ichikawa, Takafumi, Melrose, Heather L., Farrer, Matthew J., Obata, Fumiya
Publicado 2016

Neuron-autonomous susceptibility to induced synuclein aggregation is exacerbated by endogenous Lrrk2 mutations and ameliorated by Lrrk2 genetic knock-out

por MacIsaac, Sarah, Quevedo Melo, Thaiany, Zhang, Yuting, Volta, Mattia, Farrer, Matthew J, Milnerwood, Austen J
Publicado 2020

Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis

por Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, Lee, Anna, Farrer, Matthew J, Stoessl, A Jon, Sossi, Vesna
Publicado 2013

Editorial: Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson's Disease

por Farrer, Matthew J., Bardien, Soraya, Hattori, Nobutaka, Lesage, Suzanne, Ross, Owen A., Mellick, George D., Kruger, Rejko
Publicado 2021

GBA1 in Parkinson’s disease: variant detection and pathogenicity scoring matters

por Gabbert, Carolin, Schaake, Susen, Lüth, Theresa, Much, Christoph, Klein, Christine, Aasly, Jan O., Farrer, Matthew J., Trinh, Joanne
Publicado 2023

Dopamine Transporter Genetic Variants and Pesticides in Parkinson’s Disease

por Ritz, Beate R., Manthripragada, Angelika D., Costello, Sadie, Lincoln, Sarah J., Farrer, Matthew J., Cockburn, Myles, Bronstein, Jeff
Publicado 2009

α-Synuclein Suppression by Targeted Small Interfering RNA in the Primate Substantia Nigra

por McCormack, Alison L., Mak, Sally K., Henderson, Jaimie M., Bumcrot, David, Farrer, Matthew J., Di Monte, Donato A.
Publicado 2010

The Gut–Brain Axis and Its Relation to Parkinson’s Disease: A Review

por Klann, Emily M., Dissanayake, Upuli, Gurrala, Anjela, Farrer, Matthew, Shukla, Aparna Wagle, Ramirez-Zamora, Adolfo, Mai, Volker, Vedam-Mai, Vinata
Publicado 2022

Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice

por Cataldi, Stefano, Follett, Jordan, Fox, Jesse D., Tatarnikov, Igor, Kadgien, Chelsie, Gustavsson, Emil K., Khinda, Jaskaran, Milnerwood, Austen J., Farrer, Matthew J.
Publicado 2018

Mitochondrial DNA Deletions Discriminate Affected from Unaffected LRRK2 Mutation Carriers

por Ouzren, Nassima, Delcambre, Sylvie, Ghelfi, Jenny, Seibler, Philip, Farrer, Matthew J., König, Inke R., Aasly, Jan O., Trinh, Joanne, Klein, Christine, Grünewald, Anne
Publicado 2019

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy

por Bailey, Rachel M., Covy, Jason P., Melrose, Heather L., Rousseau, Linda, Watkinson, Ruth, Knight, Joshua, Miles, Sarah, Farrer, Matthew J., Dickson, Dennis W., Giasson, Benoit I., Lewis, Jada
Publicado 2013

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice

por Beccano-Kelly, Dayne A., Kuhlmann, Naila, Tatarnikov, Igor, Volta, Mattia, Munsie, Lise N., Chou, Patrick, Cao, Li-Ping, Han, Heather, Tapia, Lucia, Farrer, Matthew J., Milnerwood, Austen J.
Publicado 2014