Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

por Zhao, Bo, Liu, Pingyu, Fukumoto, Takeshi, Nacarelli, Timothy, Fatkhutdinov, Nail, Wu, Shuai, Lin, Jianhuang, Aird, Katherine M., Tang, Hsin-Yao, Liu, Qin, Speicher, David W., Zhang, Rugang
Publicado 2020

SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells

por Wu, Shuai, Fatkhutdinov, Nail, Fukumoto, Takeshi, Bitler, Benjamin G., Park, Pyoung Hwa, Kossenkov, Andrew V., Trizzino, Marco, Tang, Hsin-Yao, Zhang, Lin, Gardini, Alessandro, Speicher, David W., Zhang, Rugang
Publicado 2018

HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci

por Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Tanizawa, Hideki, Fatkhutdinov, Nail, Bitler, Benjamin G., Le, Linh, Alicea, Gretchen, Yang, Ting-Lin, Johnson, F. Brad, Noma, Ken-ichi, Zhang, Rugang
Publicado 2016

ARID1A spatially partitions interphase chromosomes

por Wu, Shuai, Fatkhutdinov, Nail, Rosin, Leah, Luppino, Jennifer M., Iwasaki, Osamu, Tanizawa, Hideki, Tang, Hsin-Yao, Kossenkov, Andrew V., Gardini, Alessandro, Noma, Ken-ichi, Speicher, David W., Joyce, Eric F., Zhang, Rugang
Publicado 2019

Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer

por Fukumoto, Takeshi, Park, Pyoung Hwa, Wu, Shuai, Fatkhutdinov, Nail, Karakashev, Sergey, Nacarelli, Timothy, Kossenkov, Andrew V., Speicher, David W., Jean, Stephanie, Zhang, Lin, Wang, Tian-Li, Shih, Ie-Ming, Conejo-Garcia, Jose R., Bitler, Benjamin G., Zhang, Rugang
Publicado 2018

ARID1A promotes genomic stability through protecting telomere cohesion

por Zhao, Bo, Lin, Jianhuang, Rong, Lijie, Wu, Shuai, Deng, Zhong, Fatkhutdinov, Nail, Zundell, Joseph, Fukumoto, Takeshi, Liu, Qin, Kossenkov, Andrew, Jean, Stephanie, Cadungog, Mark G., Borowsky, Mark E., Drapkin, Ronny, Lieberman, Paul M., Abate-Shen, Cory T., Zhang, Rugang
Publicado 2019

NAD(+) metabolism governs the proinflammatory senescence-associated secretome

por Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Schultz, David, Noma, Ken-ichi, Baur, Joseph A., Schug, Zachary, Tang, Hsin-Yao, Speicher, David W., David, Gregory, Zhang, Rugang
Publicado 2019