GLUT4 On the move

por Fazakerley, Daniel J., Koumanov, Francoise, Holman, Geoffrey D.
Publicado 2022

Insulin signalling and GLUT4 trafficking in insulin resistance

por van Gerwen, Julian, Shun-Shion, Amber S., Fazakerley, Daniel J.
Publicado 2023

Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes

por Fazakerley, Daniel J., Holman, Geoffrey D., Marley, Anna, James, David E., Stöckli, Jacqueline, Coster, Adelle C. F.
Publicado 2010

Insulin regulates Rab3–Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes

por Koumanov, Francoise, Pereira, Vinit J., Richardson, Judith D., Sargent, Samantha L., Fazakerley, Daniel J., Holman, Geoffrey D.
Publicado 2015

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2

por Humphrey, Sean J., Yang, Guang, Yang, Pengyi, Fazakerley, Daniel J., Stöckli, Jacqueline, Yang, Jean Y., James, David E.
Publicado 2013

The Role of the Niemann-Pick Disease, Type C1 Protein in Adipocyte Insulin Action

por Fletcher, Rachael, Gribben, Christopher, Ma, Xuiquan, Burchfield, James G., Thomas, Kristen C., Krycer, James R., James, David E., Fazakerley, Daniel J.
Publicado 2014

Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

por Wu, Lindsay E., Samocha-Bonet, Dorit, Whitworth, P. Tess, Fazakerley, Daniel J., Turner, Nigel, Biden, Trevor J., James, David E., Cantley, James
Publicado 2014

Correction: Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies

por Domanova, Westa, Krycer, James R., Chaudhuri, Rima, Yang, Pengyi, Vafaee, Fatemeh, Fazakerley, Daniel J., Humphrey, Sean J., James, David E., Kuncic, Zdenka
Publicado 2017

The exocyst complex is an essential component of the mammalian constitutive secretory pathway

por Pereira, Conceição, Stalder, Danièle, Anderson, Georgina S.F., Shun-Shion, Amber S., Houghton, Jack, Antrobus, Robin, Chapman, Michael A., Fazakerley, Daniel J., Gershlick, David C.
Publicado 2023

Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes

por Tan, Shi-Xiong, Ng, Yvonne, Meoli, Christopher C., Kumar, Ansu, Khoo, Poh-Sim, Fazakerley, Daniel J., Junutula, Jagath R., Vali, Shireen, James, David E., Stöckli, Jacqueline
Publicado 2012

The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes

por Chaudhuri, Rima, Krycer, James R., Fazakerley, Daniel J., Fisher-Wellman, Kelsey H., Su, Zhiduan, Hoehn, Kyle L., Yang, Jean Yee Hwa, Kuncic, Zdenka, Vafaee, Fatemeh, James, David E.
Publicado 2018

Signaling Heterogeneity is Defined by Pathway Architecture and Intercellular Variability in Protein Expression

por Norris, Dougall, Yang, Pengyi, Shin, Sung-Young, Kearney, Alison L., Kim, Hani Jieun, Geddes, Thomas, Senior, Alistair M., Fazakerley, Daniel J., Nguyen, Lan K., James, David E., Burchfield, James G.
Publicado 2021

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

por Balaban, Seher, Shearer, Robert F., Lee, Lisa S., van Geldermalsen, Michelle, Schreuder, Mark, Shtein, Harrison C., Cairns, Rose, Thomas, Kristen C., Fazakerley, Daniel J., Grewal, Thomas, Holst, Jeff, Saunders, Darren N., Hoy, Andrew J.
Publicado 2017

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

por Fazakerley, Daniel J., Minard, Annabel Y., Krycer, James R., Thomas, Kristen C., Stöckli, Jacqueline, Harney, Dylan. J., Burchfield, James G., Maghzal, Ghassan J., Caldwell, Stuart T., Hartley, Richard C., Stocker, Roland, Murphy, Michael P., James, David E.
Publicado 2018

Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate

por Duan, Xiaowen, Norris, Dougall M., Humphrey, Sean J., Yang, Pengyi, Cooke, Kristen C., Bultitude, Will P., Parker, Benjamin L., Conway, Olivia J., Burchfield, James G., Krycer, James R., Brodsky, Frances M., James, David E., Fazakerley, Daniel J.
Publicado 2022

Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo

por Kleinert, Maximilian, Sylow, Lykke, Fazakerley, Daniel J., Krycer, James R., Thomas, Kristen C., Oxbøll, Anne-Julie, Jordy, Andreas B., Jensen, Thomas E., Yang, Guang, Schjerling, Peter, Kiens, Bente, James, David E., Ruegg, Markus A., Richter, Erik A.
Publicado 2014

Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes

por Fazakerley, Daniel J., Naghiloo, Sheyda, Chaudhuri, Rima, Koumanov, Françoise, Burchfield, James G., Thomas, Kristen C., Krycer, James R., Prior, Matthew J., Parker, Ben L., Murrow, Beverley A., Stöckli, Jacqueline, Meoli, Christopher C., Holman, Geoffrey D., James, David E.
Publicado 2015

Dynamic (13)C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

por Quek, Lake-Ee, Krycer, James R., Ohno, Satoshi, Yugi, Katsuyuki, Fazakerley, Daniel J., Scalzo, Richard, Elkington, Sarah D., Dai, Ziwei, Hirayama, Akiyoshi, Ikeda, Satsuki, Shoji, Futaba, Suzuki, Kumi, Locasale, Jason W., Soga, Tomoyoshi, James, David E., Kuroda, Shinya
Publicado 2020

Dynamic (13)C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin

por Quek, Lake-Ee, Krycer, James R., Ohno, Satoshi, Yugi, Katsuyuki, Fazakerley, Daniel J., Scalzo, Richard, Elkington, Sarah D., Dai, Ziwei, Hirayama, Akiyoshi, Ikeda, Satsuki, Shoji, Futaba, Suzuki, Kumi, Locasale, Jason W., Soga, Tomoyoshi, James, David E., Kuroda, Shinya
Publicado 2020

mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

por Kleinert, Maximilian, Parker, Benjamin L., Chaudhuri, Rima, Fazakerley, Daniel J., Serup, Annette, Thomas, Kristen C., Krycer, James R., Sylow, Lykke, Fritzen, Andreas M., Hoffman, Nolan J., Jeppesen, Jacob, Schjerling, Peter, Ruegg, Markus A., Kiens, Bente, James, David E., Richter, Erik A.
Publicado 2016