VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration

por Fearnley, Gareth W., Bruns, Alexander F., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Publicado 2015

The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis

por Smith, Gina A., Fearnley, Gareth W., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan
Publicado 2015

The receptor PTPRU is a redox sensitive pseudophosphatase

por Hay, Iain M., Fearnley, Gareth W., Rios, Pablo, Köhn, Maja, Sharpe, Hayley J., Deane, Janet E.
Publicado 2020

IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis

por Bridgewood, Charlie, Fearnley, Gareth W., Berekmeri, Anna, Laws, Philip, Macleod, Tom, Ponnambalam, Sreenivasan, Stacey, Martin, Graham, Anne, Wittmann, Miriam
Publicado 2018

VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8

por Smith, Gina A., Fearnley, Gareth W., Abdul‐Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan
Publicado 2015

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function

por Smith, Gina A., Fearnley, Gareth W., Abdul-Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan
Publicado 2017

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function

por Fearnley, Gareth W., Abdul-Zani, Izma, Latham, Antony M., Hollstein, Monica C., Ladbury, John E., Wheatcroft, Stephen B., Odell, Adam F., Ponnambalam, Sreenivasan
Publicado 2019

In Silico Design and Biological Evaluation of a Dual Specificity Kinase Inhibitor Targeting Cell Cycle Progression and Angiogenesis

por Latham, Antony M., Kankanala, Jayakanth, Fearnley, Gareth W., Gage, Matthew C., Kearney, Mark T., Homer-Vanniasinkam, Shervanthi, Wheatcroft, Stephen B., Fishwick, Colin W. G., Ponnambalam, Sreenivasan
Publicado 2014

The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell–cell adhesion

por Fearnley, Gareth W, Young, Katherine A, Edgar, James R, Antrobus, Robin, Hay, Iain M, Liang, Wei-Ching, Martinez-Martin, Nadia, Lin, WeiYu, Deane, Janet E, Sharpe, Hayley J
Publicado 2019

VEGF-A isoforms differentially regulate ATF-2–dependent VCAM-1 gene expression and endothelial–leukocyte interactions

por Fearnley, Gareth W., Odell, Adam F., Latham, Antony M., Mughal, Nadeem A., Bruns, Alexander F., Burgoyne, Nicholas J., Homer-Vanniasinkam, Shervanthi, Zachary, Ian C., Hollstein, Monica C., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Publicado 2014

VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis

por Fearnley, Gareth W., Smith, Gina A., Abdul-Zani, Izma, Yuldasheva, Nadira, Mughal, Nadeem A., Homer-Vanniasinkam, Shervanthi, Kearney, Mark T., Zachary, Ian C., Tomlinson, Darren C., Harrison, Michael A., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Publicado 2016