CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation

por Olzscha, Heidi, Fedorov, Oleg, Kessler, Benedikt M., Knapp, Stefan, La Thangue, Nicholas B.
Publicado 2017

Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding

por Kempen, Herman J, Bellus, Daniel, Fedorov, Oleg, Nicklisch, Silke, Filippakopoulos, Panagis, Picaud, Sarah, Knapp, Stefan
Publicado 2013

Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1

por Santamaria, Salvatore, Fedorov, Oleg, McCafferty, John, Murphy, Gillian, Dudhia, Jayesh, Nagase, Hideaki, Yamamoto, Kazuhiro
Publicado 2017

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

por Filippakopoulos, Panagis, Picaud, Sarah, Fedorov, Oleg, Keller, Marco, Wrobel, Matthias, Morgenstern, Olaf, Bracher, Franz, Knapp, Stefan
Publicado 2012

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein

por Carr, Simon M, Munro, Shonagh, Sagum, Cari A, Fedorov, Oleg, Bedford, Mark T, La Thangue, Nicholas B
Publicado 2017

Flagellar filament bio-templated inorganic oxide materials – towards an efficient lithium battery anode

por Beznosov, Sergei N., Veluri, Pavan S., Pyatibratov, Mikhail G., Chatterjee, Abhijit, MacFarlane, Douglas R., Fedorov, Oleg V., Mitra, Sagar
Publicado 2015

Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

por Tallant, Cynthia, Valentini, Erica, Fedorov, Oleg, Overvoorde, Lois, Ferguson, Fleur M., Filippakopoulos, Panagis, Svergun, Dmitri I., Knapp, Stefan, Ciulli, Alessio
Publicado 2015

Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

por Vidler, Lewis R., Filippakopoulos, Panagis, Fedorov, Oleg, Picaud, Sarah, Martin, Sarah, Tomsett, Michael, Woodward, Hannah, Brown, Nathan, Knapp, Stefan, Hoelder, Swen
Publicado 2013

Salt‐dependent regulation of archaellins in Haloarcula marismortui

por Syutkin, Alexey S., van Wolferen, Marleen, Surin, Alexey K., Albers, Sonja‐Verena, Pyatibratov, Mikhail G., Fedorov, Oleg V., Quax, Tessa E. F.
Publicado 2018

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs

por Eswaran, Jeyanthy, Lee, Wen Hwa, Debreczeni, Judit É., Filippakopoulos, Panagis, Turnbull, Andrew, Fedorov, Oleg, Deacon, Sean W., Peterson, Jeffrey R., Knapp, Stefan
Publicado 2007

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

por Schuller, Marion, Zarganes-Tzitzikas, Tryfon, Bennett, James, De Cesco, Stephane, Fearon, Daren, von Delft, Frank, Fedorov, Oleg, Brennan, Paul E., Ahel, Ivan
Publicado 2023

Structural Comparison of Human Mammalian Ste20-Like Kinases

por Record, Christopher J., Chaikuad, Apirat, Rellos, Peter, Das, Sanjan, Pike, Ashley C. W., Fedorov, Oleg, Marsden, Brian D., Knapp, Stefan, Lee, Wen Hwa
Publicado 2010

7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes†

por Huber, Kilian, Brault, Laurent, Fedorov, Oleg, Gasser, Christelle, Filippakopoulos, Panagis, Bullock, Alex N., Fabbro, Doriano, Trappe, Jörg, Schwaller, Jürg, Knapp, Stefan, Bracher, Franz
Publicado 2011

Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain

por Chaikuad, Apirat, Lang, Steffen, Brennan, Paul E., Temperini, Claudia, Fedorov, Oleg, Hollander, Johan, Nachane, Ruta, Abell, Chris, Müller, Susanne, Siegal, Gregg, Knapp, Stefan
Publicado 2016

Structural and Functional Characterization of the Human Protein Kinase ASK1

por Bunkoczi, Gabor, Salah, Eidarus, Filippakopoulos, Panagis, Fedorov, Oleg, Müller, Susanne, Sobott, Frank, Parker, Sirlester A., Zhang, Haifeng, Min, Wang, Turk, Benjamin E., Knapp, Stefan
Publicado 2007

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

por Sansook, Supojjanee, Ocasio, Cory A., Day, Iain J., Tizzard, Graham J., Coles, Simon J., Fedorov, Oleg, Bennett, James M., Elkins, Jonathan M., Spencer, John
Publicado 2017

Correction: Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

por Sansook, Supojjanee, Ocasio, Cory A., Day, Iain J., Tizzard, Graham J., Coles, Simon J., Fedorov, Oleg, Bennett, James M., Elkins, Jonathan M., Spencer, John
Publicado 2017

3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

por Hewings, David S., Wang, Minghua, Philpott, Martin, Fedorov, Oleg, Uttarkar, Sagar, Filippakopoulos, Panagis, Picaud, Sarah, Vuppusetty, Chaitanya, Marsden, Brian, Knapp, Stefan, Conway, Stuart J., Heightman, Tom D.
Publicado 2011

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

por Ferguson, Fleur M., Fedorov, Oleg, Chaikuad, Apirat, Philpott, Martin, Muniz, Joao R. C., Felletar, Ildiko, von Delft, Frank, Heightman, Tom, Knapp, Stefan, Abell, Chris, Ciulli, Alessio
Publicado 2013

Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

por Fedorov, Oleg, Huber, Kilian, Eisenreich, Andreas, Filippakopoulos, Panagis, King, Oliver, Bullock, Alex N., Szklarczyk, Damian, Jensen, Lars J., Fabbro, Doriano, Trappe, Jörg, Rauch, Ursula, Bracher, Franz, Knapp, Stefan
Publicado 2011