The “rights” of precision drug development for Alzheimer’s disease

por Cummings, Jeffrey, Feldman, Howard H., Scheltens, Philip
Publicado 2019

Definitions of dementia and predementia states in Alzheimer's disease and vascular cognitive impairment: consensus from the Canadian conference on diagnosis of dementia

por Chertkow, Howard, Feldman, Howard H, Jacova, Claudia, Massoud, Fadi
Publicado 2013

Exploring Social Cognition Tests to Differentiate Frontotemporal Dementia from Depression: A Two-Step Pilot Study

por Lichtenstein, Maya L., Stewart, Peter V., Kirchner, H. Lester, Finney, Glen, Feldman, Howard H.
Publicado 2023

Pharmacological thiamine levels as a therapeutic approach in Alzheimer's disease

por Gibson, Gary E., Feldman, Howard H., Zhang, Sheng, Flowers, Sarah A., Luchsinger, José A.
Publicado 2022

Adaptive crossover designs for assessment of symptomatic treatments targeting behaviour in neurodegenerative disease: a phase 2 clinical trial of intranasal oxytocin for frontotemp...

por Finger, Elizabeth, Berry, Scott, Cummings, Jeffrey, Coleman, Kristy, Hsiung, Robin, Feldman, Howard H., Boxer, Adam
Publicado 2018

Enriching the design of Alzheimer's disease clinical trials: Application of the polygenic hazard score and composite outcome measures

por Banks, Sarah J., Qiu, Yuqi, Fan, Chun Chieh, Dale, Anders M., Zou, Jingjing, Askew, Brianna, Feldman, Howard H.
Publicado 2020

Development of a novel cognitive composite outcome to assess therapeutic effects of exercise in the EXERT trial for adults with MCI: The ADAS‐Cog‐Exec

por Jacobs, Diane M., Thomas, Ronald G., Salmon, David P., Jin, Shelia, Feldman, Howard H., Cotman, Carl W., Baker, Laura D.
Publicado 2020

Multidomain trials to prevent dementia: addressing methodological challenges

por Montero-Odasso, Manuel, Zou, G Y, Kamkar, Nellie, Feldman, Howard H., Belleville, Sylvie, Chertkow, Howard, Nygaard, Haakon B, Son, Surim, Speechley, Mark
Publicado 2022

Home EEG sleep assessment shows reduced slow‐wave sleep in mild–moderate Alzheimer's disease

por Kent, Brianne A., Casciola, Amelia A., Carlucci, Sebastiano K., Chen, Meghan, Stager, Sam, Mirian, Maryam S., Slack, Penelope, Valerio, Jason, McKeown, Martin J., Feldman, Howard H., Nygaard, Haakon B.
Publicado 2022

Evaluation of bumetanide as a potential therapeutic agent for Alzheimer’s disease

por Boyarko, Ben, Podvin, Sonia, Greenberg, Barry, Momper, Jeremiah D., Huang, Yadong, Gerwick, William H., Bang, Anne G., Quinti, Luisa, Griciuc, Ana, Kim, Doo Yeon, Tanzi, Rudolph E., Feldman, Howard H., Hook, Vivian
Publicado 2023

Rasagiline effects on glucose metabolism, cognition, and tau in Alzheimer's dementia

por Matthews, Dawn C., Ritter, Aaron, Thomas, Ronald G., Andrews, Randolph D., Lukic, Ana S., Revta, Carolyn, Kinney, Jefferson W., Tousi, Babak, Leverenz, James B., Fillit, Howard, Zhong, Kate, Feldman, Howard H., Cummings, Jeffrey
Publicado 2021

Gray matter changes in asymptomatic C9orf72 and GRN mutation carriers

por Popuri, Karteek, Dowds, Emma, Beg, Mirza Faisal, Balachandar, Rakesh, Bhalla, Mahadev, Jacova, Claudia, Buller, Adrienne, Slack, Penny, Sengdy, Pheth, Rademakers, Rosa, Wittenberg, Dana, Feldman, Howard H., Mackenzie, Ian R., Hsiung, Ging-Yuek R.
Publicado 2018

Impact of potential modifications to Alzheimer’s disease clinical trials in response to disruption by COVID-19: a simulation study

por Schneider, Lon S., Qiu, Yuqi, Thomas, Ronald G., Evans, Carol, Jacobs, Diane M., Jin, Shelia, Kaye, Jeffrey A., LaCroix, Andrea Z., Messer, Karen, Salmon, David P., Sano, Mary, Schafer, Kimberly, Feldman, Howard H.
Publicado 2021

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

por Jack, Clifford R., Bennett, David A., Blennow, Kaj, Carrillo, Maria C., Feldman, Howard H., Frisoni, Giovanni B., Hampel, Harald, Jagust, William J., Johnson, Keith A., Knopman, David S., Petersen, Ronald C., Scheltens, Philip, Sperling, Reisa A., Dubois, Bruno
Publicado 2016

T2 Protect AD: Achieving a rapid recruitment timeline in a multisite clinical trial for individuals with mild to moderate Alzheimer's disease

por Shadyab, Aladdin H., LaCroix, Andrea Z., Matthews, Genevieve, Bennett, Daniel, Shadyab, Alexandre A., Tan, Donna, Thomas, Ronald G., Mason, Jennifer, Lopez, Alex, Askew, Brianna, Donahue, Lia, Kaplita, Stephen, Qureshi, Irfan A., Huisa, Branko, Feldman, Howard H.
Publicado 2022

Committee on High‐quality Alzheimer's Disease Studies (CHADS) consensus report

por Jicha, Greg A., Abner, Erin L., Arnold, Steven E., Carrillo, Maria C., Dodge, Hiroko H., Edland, Steven D., Fargo, Keith N., Feldman, Howard H., Goldstein, Larry B., Hendrix, James, Peters, Ruth, Robillard, Julie M., Schneider, Lon S., Titiner, Jodi R., Weber, Christopher J.
Publicado 2021

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

por Frew, Jonathan, Baradaran-Heravi, Alireza, Balgi, Aruna D., Wu, Xiujuan, Yan, Tyler D., Arns, Steve, Shidmoossavee, Fahimeh S., Tan, Jason, Jaquith, James B., Jansen-West, Karen R., Lynn, Francis C., Gao, Fen-Biao, Petrucelli, Leonard, Feldman, Howard H., Mackenzie, Ian R., Roberge, Michel, Nygaard, Haakon B.
Publicado 2020

Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A Prospective 12-M...

por Feldman, Howard H., Belleville, S., Nygaard, H. B., Montero-Odasso, M., Durant, J., Lupo, J.-L., Revta, C., Chan, S., Cuesta, M., Slack, P. J., Winer, S., Brewster, P. W. H., Hofer, S. M., Lim, A., Centen, A., Jacobs, D. M., Anderson, N. D., Walker, J. D., Speechley, M. R., Zou, G. Y., Chertkow, H.
Publicado 2023

Value-Generating Exploratory Trials in Neurodegenerative Dementias

por Friedman, Lauren G., McKeehan, Nicholas, Hara, Yuko, Cummings, Jeffrey L., Matthews, Dawn C., Zhu, Jian, Mohs, Richard C., Wang, Deli, Hendrix, Suzanne B., Quintana, Melanie, Schneider, Lon S., Grundman, Michael, Dickson, Samuel P., Feldman, Howard H., Jaeger, Judith, Finger, Elizabeth C., Ryan, J. Michael, Niehoff, Debra, Dickinson, Susan L-J., Markowitz, Jessica T., Owen, Meriel, Travaglia, Alessio, Fillit, Howard M.
Publicado 2021

Recruitment of a multi‐site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial

por Shadyab, Aladdin H., LaCroix, Andrea Z., Feldman, Howard H., van Dyck, Christopher H., Okonkwo, Ozioma C., Tam, Steven P., Fairchild, J. Kaci, Welsh‐Bohmer, Kathleen A., Matthews, Genevieve, Bennett, Daniel, Shadyab, Alexandre A., Schafer, Kimberly A., Morrison, Rosemary H., Kipperman, Sean A., Mason, Jennifer, Tan, Donna, Thomas, Ronald G., Cotman, Carl W., Baker, Laura D.
Publicado 2021